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Mehreen Ahmed et al.
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Martin C. S. Wong et al.
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Justin Guinney et al.
NATURE MEDICINE (2015)
The Path to Cancer - Three Strikes and You're Out
Bert Vogelstein et al.
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Meriam Ayadi et al.
ONCOTARGET (2015)
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Lloyd Pereira et al.
FRONTIERS IN ONCOLOGY (2015)
Boosting Wnt activity during colorectal cancer progression through selective hypermethylation of Wnt signaling antagonists
Ana-Luisa Silva et al.
BMC CANCER (2014)
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Rebecca Siegel et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2014)
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Diwakar R. Pattabiraman et al.
NATURE REVIEWS DRUG DISCOVERY (2014)
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Gonzalo Recondo et al.
WORLD JOURNAL OF GASTROINTESTINAL ONCOLOGY (2014)
Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties
Sarah Schwitalla et al.
CELL (2013)
p53 regulates nuclear GSK-3 levels through miR-34-mediated Axin2 suppression in colorectal cancer cells
Nam Hee Kim et al.
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Wnt/beta-Catenin Signaling and Small Molecule Inhibitors
Andrey Voronkov et al.
CURRENT PHARMACEUTICAL DESIGN (2013)
MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis
Keun Hur et al.
GUT (2013)
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Jan Paul Medema
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The epigenetics of epithelial-mesenchymal plasticity in cancer
Wai Leong Tam et al.
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The role of EZH2 in tumour progression
C-J Chang et al.
BRITISH JOURNAL OF CANCER (2012)
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Jueng Soo You et al.
CANCER CELL (2012)
Evolvement of the treatment paradigm for metastatic colon cancer. From chemotherapy to targeted therapy
Santiago Aparo et al.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2012)
Epigenetics of Colorectal Cancer
Ajay Goel et al.
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Expression of miR-34 is lost in colon cancer which can be re-expressed by a novel agent CDF
Sanchita Roy et al.
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LGR5 Interacts and Cointernalizes with Wnt Receptors To Modulate Wnt/β-Catenin Signaling
Kendra S. Carmon et al.
MOLECULAR AND CELLULAR BIOLOGY (2012)
miR-34 and SNAIL form a double-negative feedback loop to regulate epithelial-mesenchymal transitions
Helge Siemens et al.
CELL CYCLE (2011)
The Nodal inhibitor Lefty is negatively modulated by the microRNA miR-302 in human embryonic stem cells
Alicia Barroso-delJesus et al.
FASEB JOURNAL (2011)
CpG islands and the regulation of transcription
Aimee M. Deaton et al.
GENES & DEVELOPMENT (2011)
The mechanisms of cancer immunoescape and development of overcoming strategies
Tomonori Yaguchi et al.
INTERNATIONAL JOURNAL OF HEMATOLOGY (2011)
Cancer epigenetics reaches mainstream oncology
Manuel Rodriguez-Paredes et al.
NATURE MEDICINE (2011)
Targeting cancer stem cells by inhibiting Wnt, notch, and Hedgehog pathways
Naoko Takebe et al.
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Sebastian S. Zeki et al.
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Leonel F. Hernandez-Aya et al.
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Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1
Wenchu Lin et al.
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The Histone Demethylase RBP2 Is Overexpressed in Gastric Cancer and Its Inhibition Triggers Senescence of Cancer Cells
Jiping Zeng et al.
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Wnt activity defines colon cancer stem cells and is regulated by the microenvironment
Louis Vermeulen et al.
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Jeffrey M. Friedman et al.
CANCER RESEARCH (2009)
Aberrant Methylation of APC, MGMT, RASSF2A, and Wif-1 Genes in Plasma as a Biomarker for Early Detection of Colorectal Cancer
Bo Bin Lee et al.
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Recruitment of Polycomb group complexes and their role in the dynamic regulation of cell fate choice
Bernd Schuettengruber et al.
DEVELOPMENT (2009)
Molecular Origins of Cancer: Molecular Basis of Colorectal Cancer.
Sanford D. Markowitz et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Epigenetically reprogramming metastatic tumor cells with an embryonic microenvironment
Fabricio F. Costa et al.
EPIGENOMICS (2009)
Colorectal Cancer Epidemiology: Incidence, Mortality, Survival, and Risk Factors
Fatima Haggar et al.
Clinics in Colon and Rectal Surgery (2009)
Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits
Kornelia Polyak et al.
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Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2
Diego Pasini et al.
GENES & DEVELOPMENT (2008)
Survival following recurrence in stage II and III colon cancer:: Findings from the ACCENT data set
Michael J. O'Connell et al.
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Epithelial-mesenchymal and mesenchymal - Epithelial transitions in carcinoma progression
Honor Hugo et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2007)
Comparing the DNA hypermethylome with gene mutations in human colorectal cancer
Kornel E. Schuebel et al.
PLOS GENETICS (2007)
Wnt/β-catenin signaling in cancer stemness and malignant behavior
Riccardo Fodde et al.
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Epigenetic stem cell signature in cancer
Martin Widschwendter et al.
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The canonical Wnt signalling pathway and its APC partner in colon cancer development
Jean Schneikert et al.
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Colorectal cancer and genetic alterations in the Wnt pathway
S. Segditsas et al.
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Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer
O. Aguilera et al.
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The epigenetic progenitor origin of human cancer
AP Feinberg et al.
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Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer
H Suzuki et al.
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Opinion - CpG island methylator phenotype in cancer
JP Issa
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Prevalence of somatic alterations in the colorectal cancer cell genome
TL Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Regulation of β-catenin structure and activity by tyrosine phosphorylation
J Piedra et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Linking colorectal cancer to Wnt signaling
M Bienz et al.
CELL (2000)