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JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Impaired P2X1 Receptor-Mediated Adhesion in Eosinophils from Asthmatic Patients
Adam Wright et al.
JOURNAL OF IMMUNOLOGY (2016)
A Critical Role for P2X7 Receptor-Induced VCAM-1 Shedding and Neutrophil Infiltration during Acute Lung Injury
Amarjit Mishra et al.
JOURNAL OF IMMUNOLOGY (2016)
ATP-Induced Inflammation Drives Tissue-Resident Th17 Cells in Metabolically Unhealthy Obesity
Julieta B. Pandolfi et al.
JOURNAL OF IMMUNOLOGY (2016)
Upregulation of P2Y2 nucleotide receptor in human hepatocellular carcinoma cells
Eunyoung Tak et al.
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH (2016)
Analogs of the ATP-Sensitive Potassium (KATP) Channel Opener Cromakalim with in Vivo Ocular Hypotensive Activity
Uttio Roy Chowdhury et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Discovery and Preclinical Characterization of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic Acid (PF-06409577), a Direct Activator of Adenosine Monophosphate-activated Protein Kinase (AMPK), for the Potential Treatment of Diabetic Nephropathy
Kimberly O. Cameron et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Extracellular nucleotide regulation and signaling in cardiac fibrosis
Tatiana Novitskaya et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2016)
Enhanced A(2A) adenosine receptor-mediated increase in coronary flow in type I diabetic mice
Hicham Labazi et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2016)
ATP sensitive K+ channels are critical for maintaining myocardial perfusion and high energy phosphates in the failing heart
Mohammad N. Jameel et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2016)
Adenosine kinase facilitated astrogliosis-induced cortical neuronal death in traumatic brain injury
Wei Jin et al.
JOURNAL OF MOLECULAR HISTOLOGY (2016)
Role of purinergic P2X4 receptors in regulating striatal dopamine homeostasis and dependent behaviors
Sheraz Khoja et al.
JOURNAL OF NEUROCHEMISTRY (2016)
How does adenosine control neuronal dysfunction and neurodegeneration?
Rodrigo A. Cunha
JOURNAL OF NEUROCHEMISTRY (2016)
Dual roles of the adenosine A2a receptor in autoimmune neuroinflammation
J. Ingwersen et al.
JOURNAL OF NEUROINFLAMMATION (2016)
Olig2-Targeted G-Protein-Coupled Receptor Gpr17 Regulates Oligodendrocyte Survival in Response to Lysolecithin-Induced Demyelination
Zhimin Ou et al.
JOURNAL OF NEUROSCIENCE (2016)
Combined electrophysiological and biosensor approaches to study purinergic regulation of epileptiform activity in cortical tissue
Bruno G. Frenguelli et al.
JOURNAL OF NEUROSCIENCE METHODS (2016)
Purinergic Signaling in Epilepsy
Francois Rassendren et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2016)
Role of A3 adenosine receptor in diabetic neuropathy
Heng Yan et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2016)
Localization and Possible Function of P2X Receptors in Normal and Diseased Retinae
Tracy Ho et al.
JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS (2016)
Treatment of Retinal Disorders with Purinergic Drugs: Beyond Receptors
Jonathan M. Beckel et al.
JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS (2016)
Purinergic Signaling in Corneal Wound Healing: A Tale of 2 Receptors
Martin S. Minns et al.
JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS (2016)
On the mechanism of gating defects caused by the R117H mutation in cystic fibrosis transmembrane conductance regulator
Ying-Chun Yu et al.
JOURNAL OF PHYSIOLOGY-LONDON (2016)
Long-Term P2Y12-Receptor Antagonists in Post-Myocardial Infarction Patients Facing a New Trilemma?
Dimitrios Alexopoulos et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2016)
IL-1ra Secreted by ATP-Induced P2Y2 Negatively Regulates MUC5AC Overproduction via PLCβ3 during Airway Inflammation
Jee-Yeong Jeong et al.
MEDIATORS OF INFLAMMATION (2016)
Participation of purines in the modulation of inflammatory response in rats experimentally infected by Cryptococcus neoformans
Maria Isabel de Azevedo et al.
MICROBIAL PATHOGENESIS (2016)
Ischemia triggered ATP release through Pannexin-1 channel by myocardial cells activates sympathetic fibers
Feng Dong et al.
MICROVASCULAR RESEARCH (2016)
P2X7 receptor knockout prevents streptozotocin-induced type 1 diabetes in mice
Flayia Sarmento Vieira et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2016)
Expression of ATP binding cassette E1 enhances viability and invasiveness of lung adenocarcinoma cells in vitro
Ye Tian et al.
MOLECULAR MEDICINE REPORTS (2016)
Purinergic receptors in the carotid body as a new drug target for controlling hypertension
Wioletta Pijacka et al.
NATURE MEDICINE (2016)
Upregulated P2X3 Receptor Expression in Patients with Intractable Temporal Lobe Epilepsy and in a Rat Model of Epilepsy
Xin Zhou et al.
NEUROCHEMICAL RESEARCH (2016)
Purinergic signaling in retinal degeneration and regeneration
Andreas Reichenbach et al.
NEUROPHARMACOLOGY (2016)
CNS remyelination as a novel reparative approach to neurodegenerative diseases: The roles of purinergic signaling and the P2Y-like receptor GPR17
Marta Fumagalli et al.
NEUROPHARMACOLOGY (2016)
Purines in neurodegeneration and neuroregeneration
Peter Illes et al.
NEUROPHARMACOLOGY (2016)
Purinergic signalling in brain ischemia
Felicita Pedata et al.
NEUROPHARMACOLOGY (2016)
Purinergic signaling in Parkinson's disease. Relevance for treatment
Gemma Navarro et al.
NEUROPHARMACOLOGY (2016)
Allosteric mechanisms within the adenosine A2A -dopamine D2 receptor heterotetramer
Sergi Ferre et al.
NEUROPHARMACOLOGY (2016)
Purinergic receptors in psychiatric disorders
Ute Kruegel
NEUROPHARMACOLOGY (2016)
ATPergic signalling during seizures and epilepsy
Tobias Engel et al.
NEUROPHARMACOLOGY (2016)
Purine nucleosides in neuroregeneration and neuroprotection
Filipa F. Ribeiro et al.
NEUROPHARMACOLOGY (2016)
Positive allosteric modulation of A1 adenosine receptors as a novel and promising therapeutic strategy for anxiety
Fabrizio Vincenzi et al.
NEUROPHARMACOLOGY (2016)
ATP leakage induces P2XR activation and contributes to acute synaptic excitotoxiciw induced by soluble oligomers of β-amyloid peptide in hippocampal neurons
F. Saez-Orellana et al.
NEUROPHARMACOLOGY (2016)
Purinergic mechanisms in neuroinflammation: An update from molecules to behavior
Edward Beamer et al.
NEUROPHARMACOLOGY (2016)
Purinergic contribution to amyotrophic lateral sclerosis
Cinzia Volonte et al.
NEUROPHARMACOLOGY (2016)
Medicinal chemistry of adenosine, P2Y and P2X receptors
Kenneth A. Jacobson et al.
NEUROPHARMACOLOGY (2016)
An introduction to the roles of purinergic signalling in neurodegeneration, neuroprotection and neuroregeneration
Geoffrey Burnstock
NEUROPHARMACOLOGY (2016)
Purinergic receptors as potential therapeutic targets in Alzheimer's disease
Lucas T. Woods et al.
NEUROPHARMACOLOGY (2016)
Neuron-microglia interaction by purinergic signaling in neuropathic pain following neurodegeneration
Makoto Tsuda et al.
NEUROPHARMACOLOGY (2016)
ACTIVATION OF MICROGLIAL P2Y12 RECEPTOR IS REQUIRED FOR OUTWARD POTASSIUM CURRENTS IN RESPONSE TO NEURONAL INJURY
P. Swiatkowski et al.
NEUROSCIENCE (2016)
NEUROVASCULAR CONTRIBUTIONS TO MIGRAINE: MOVING BEYOND VASODILATION
Blaine Jacobs et al.
NEUROSCIENCE (2016)
LOSS OF INHIBITION BY BRAIN NATRIURETIC PEPTIDE OVER P2X3 RECEPTORS CONTRIBUTES TO ENHANCED SPIKE FIRING OF TRIGEMINAL GANGLION NEURONS IN A MOUSE MODEL OF FAMILIAL HEMIPLEGIC MIGRAINE TYPE-1
Anna Marchenkova et al.
NEUROSCIENCE (2016)
Extracellular levels of ATP and acetylcholine during lithium-pilocarpine induced status epilepticus in rats
Jana Lietsche et al.
NEUROSCIENCE LETTERS (2016)
P2X7 as a new target for chrysophanol to treat lipopolysaccharide-induced depression in mice
Kai Zhang et al.
NEUROSCIENCE LETTERS (2016)
Down-regulation of purinergic P2X7 receptor expression and intracellular calcium dysregulation in peripheral blood mononuclear cells of patients with amyotrophic lateral sclerosis
Jingyu Liu et al.
NEUROSCIENCE LETTERS (2016)
Adenosine Hypothesis of Antipsychotic Drugs Revisited: Pharmacogenomics Variation in Nonacute Schizophrenia
Arijana Turcin et al.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY (2016)
Evaluation of antidepressant-like and anxiolytic-like activity of purinedione-derivatives with affinity for adenosine A2A receptors in mice
Anna Dziubina et al.
PHARMACOLOGICAL REPORTS (2016)
Cocaine self-administration differentially affects allosteric A2A-D2 receptor-receptor interactions in the striatum. Relevance for cocaine use disorder
Julia Pintsuk et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2016)
Short- and long-term (trophic) purinergic signalling
Geoffrey Burnstock
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2016)
Pharmacology of the Adenosine A3 Receptor in the Vasculature and Essential Hypertension
Ming-Fen Ho et al.
PLOS ONE (2016)
Increased Urinary Adenosine Triphosphate in Patients With Bladder Outlet Obstruction Due to Benign Prostate Hyperplasia
Miguel Silva-Ramos et al.
PROSTATE (2016)
Peripheral adenosine levels in euthymic patients with bipolar disorder
Carolina Gubert et al.
PSYCHIATRY RESEARCH (2016)
Mechanisms of the psychostimulant effects of caffeine: implications for substance use disorders
Sergi Ferre
PSYCHOPHARMACOLOGY (2016)
Saffron reduces ATP-induced retinal cytotoxicity by targeting P2X7 receptors
Lucia Corso et al.
PURINERGIC SIGNALLING (2016)
Thymidine 5′-O-monophosphorothioate induces HeLa cell migration by activation of the P2Y6 receptor
Edyta Gendaszewska-Darmach et al.
PURINERGIC SIGNALLING (2016)
Long noncoding NONRATT021972 siRNA normalized abnormal sympathetic activity mediated by the upregulation of P2X7 receptor in superior cervical ganglia after myocardial ischemia
Guihua Tu et al.
PURINERGIC SIGNALLING (2016)
Coupling switch of P2Y-IP3 receptors mediates differential Ca2+ signaling in human embryonic stem cells and derived cardiovascular progenitor cells
Jijun Huang et al.
PURINERGIC SIGNALLING (2016)
Lack of functional P2X7 receptor aggravates brain edema development after middle cerebral artery occlusion
Melanie Kaiser et al.
PURINERGIC SIGNALLING (2016)
P2X ion channel receptors and inflammation
Geoffrey Burnstock
PURINERGIC SIGNALLING (2016)
Nucleotide homeostasis and purinergic nociceptive signaling in rat meninges in migraine-like conditions
Gennady G. Yegutkin et al.
PURINERGIC SIGNALLING (2016)
Signaling pathways involving adenosine A2A and A2B receptors in wound healing and fibrosis
Gibran Shaikh et al.
PURINERGIC SIGNALLING (2016)
Exogenously administered adenosine attenuates renal damage in streptozotocin-induced diabetic rats
Emin Taskiran et al.
RENAL FAILURE (2016)
Adenosine Triphosphate Regresses Endometrial Explants in a Rat Model of Endometriosis
Chen Zhang et al.
REPRODUCTIVE SCIENCES (2016)
Nanobodies that block gating of the P2X7 ion channel ameliorate inflammation
Welbeck Danquah et al.
SCIENCE TRANSLATIONAL MEDICINE (2016)
Effects of perinatal exposure to lead (Pb) on purine receptor expression in the brain and gliosis in rats tolerant to morphine analgesia
Irena Baranowska-Bosiacka et al.
TOXICOLOGY (2016)
Purinergic Signaling During Immune Cell Trafficking
Davide Ferrari et al.
TRENDS IN IMMUNOLOGY (2016)
MicroRNAs Modulate the Purinergic Signaling Network
Davide Ferrari et al.
TRENDS IN MOLECULAR MEDICINE (2016)
Adenosine as a Multi-Signalling Guardian Angel in Human Diseases: When, Where and How Does it Exert its Protective Effects?
Pier Andrea Borea et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2016)
Elevated synovial fluid concentration of adenosine triphosphate in dogs with osteoarthritis or sodium urate-induced synovitis of the stifle
Bryan T. Torres et al.
VETERINARY AND COMPARATIVE ORTHOPAEDICS AND TRAUMATOLOGY (2016)
Ionotropic Purinergic Receptors P2X4 and P2X7: Proviral or Antiviral? An Insight into P2X Receptor Signaling and Hepatitis C Virus Infection
Sobia Manzoor et al.
VIRAL IMMUNOLOGY (2016)
Analysis on mechanism of ATP-sensitive K+ channel opener natakalim improving congestive heart failure after myocardial infarction
Feng Jin
EXPERIMENTAL AND THERAPEUTIC MEDICINE (2016)
Neutrophil P2X7 receptors mediate NLRP3 inflammasome-dependent IL-1β secretion in response to ATP
Mausita Karmakar et al.
NATURE COMMUNICATIONS (2016)
Important roles of P2Y receptors in the inflammation and cancer of digestive system
Han-Xing Wan et al.
ONCOTARGET (2016)
Blunted dynamics of adenosine A2A receptors is associated with increased susceptibility to Candida albicans infection in the elderly
Lisa Rodrigues et al.
ONCOTARGET (2016)
Chemotherapy-induced uridine diphosphate release promotes breast cancer metastasis through P2Y6 activation
Xiaobin Ma et al.
ONCOTARGET (2016)
Adenosine A3 receptor elicits chemoresistance mediated by multiple resistance-associated protein-1 in human glioblastoma stem-like cells
Angelo Torres et al.
ONCOTARGET (2016)
Adenosine A2A Receptor Blockade Prevents Rotenone-Induced Motor Impairment in a Rat Model of Parkinsonism
Ahmed M. Fathalla et al.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2016)
Nociceptive transmission and modulation via P2X receptors in central pain syndrome
Yung-Hui Kuan et al.
MOLECULAR BRAIN (2016)
LncRNA NONRATT021972 siRNA regulates neuropathic pain behaviors in type 2 diabetic rats through the P2X7 receptor in dorsal root ganglia
Shuangmei Liu et al.
MOLECULAR BRAIN (2016)
Purinergic signaling-induced neuroinflammation and status epilepticus
Tobias Engel
EXPERT REVIEW OF NEUROTHERAPEUTICS (2016)
The Adenosinergic System in Diabetic Retinopathy
J. Vindeirinho et al.
JOURNAL OF DIABETES RESEARCH (2016)
P2Y Receptors in Synaptic Transmission and Plasticity: Therapeutic Potential in Cognitive Dysfunction
Segundo J. Guzman et al.
NEURAL PLASTICITY (2016)
Purinergic Signaling in Gut Inflammation: The Role of Connexins and Pannexins
Erica F. Diezmos et al.
FRONTIERS IN NEUROSCIENCE (2016)
Colligative Property of ATP: Implications for Enteric Purinergic Neuromuscular Neurotransmission
Arun Chaudhury et al.
FRONTIERS IN PHYSIOLOGY (2016)
Critical role for adenosine receptor A2a in β-cell proliferation
Nadja Schulz et al.
MOLECULAR METABOLISM (2016)
Elevated circulating adenosine deaminase activity in women with preeclampsia: association with pro-inflammatory cytokine production and uric acid levels
Vanessa S. Giorgi et al.
PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH (2016)
Danger signals, inflammasomes, and the intricate intracellular lives of chlamydiae
Matthew A. Pettengill et al.
BIOMEDICAL JOURNAL (2016)
Purinergic signaling in infection and autoimmune disease
Luiz Eduardo Baggio Savio et al.
BIOMEDICAL JOURNAL (2016)
Purinergic signaling in schistosomal infection
Claudia Lucia Martins Silva
BIOMEDICAL JOURNAL (2016)
Trichomoniasis immunity and the involvement of the purinergic signaling
Camila Braz Menezes et al.
BIOMEDICAL JOURNAL (2016)
Purinergic signaling during Porphyromonas gingivalis infection
Cassio Luiz Coutinho Almeida-da-Silva et al.
BIOMEDICAL JOURNAL (2016)
Purinergic signaling and infection by Leishmania: A new approach to evasion of the immune response
Amanda Braga de Figueiredo et al.
BIOMEDICAL JOURNAL (2016)
Role of P2 Receptors as Modulators of Rat Eosinophil Recruitment in Allergic Inflammation
Anael Viana Pinto Alberto et al.
PLOS ONE (2016)
Co-Expression of Wild-Type P2X7R with Gln460Arg Variant Alters Receptor Function
Fernando Aprile-Garcia et al.
PLOS ONE (2016)
Reduced Adenosine Uptake and Its Contribution to Signaling that Mediates Profibrotic Activation in Renal Tubular Epithelial Cells: Implication in Diabetic Nephropathy
Catalina Kretschmar et al.
PLOS ONE (2016)
Blockade of Extracellular ATP Effect by Oxidized ATP Effectively Mitigated Induced Mouse Experimental Autoimmune Uveitis (EAU)
Ronglan Zhao et al.
PLOS ONE (2016)
P2X7R-Panx1 Complex Impairs Bone Mechanosignaling under High Glucose Levels Associated with Type-1 Diabetes
Zeynep Seref-Ferlengez et al.
PLOS ONE (2016)
Protein Profiling of Bladder Urothelial Cell Carcinoma
Jinghai Hu et al.
PLOS ONE (2016)
A2A Adenosine Receptor Antagonism Reverts the Blood-Brain Barrier Dysfunction Induced by Sleep Restriction
Gabriela Hurtado-Alvarado et al.
PLOS ONE (2016)
An Anti-Parkinson's Disease Drug via Targeting Adenosine A2A Receptor Enhances Amyloid-β Generation and γ-Secretase Activity
Jing Lu et al.
PLOS ONE (2016)
P2X7 Receptor Suppression Preserves Blood-Brain Barrier through Inhibiting RhoA Activation after Experimental Intracerebral Hemorrhage in Rats
Hengli Zhao et al.
SCIENTIFIC REPORTS (2016)
Membrane omega-3 fatty acids modulate the oligomerisation kinetics of adenosine A2A and dopamine D2 receptors
Ramon Guixa-Gonzalez et al.
SCIENTIFIC REPORTS (2016)
Extracellular ATP mediates inflammatory responses in colitis via P2 x 7 receptor signaling
Ping Wan et al.
SCIENTIFIC REPORTS (2016)
The P2X4 receptor is required for neuroprotection via ischemic preconditioning
Tomohiko Ozaki et al.
SCIENTIFIC REPORTS (2016)
MicroRNA-16 is putatively involved in the NF-κB pathway regulation in ulcerative colitis through adenosine A2a receptor (A2aAR) mRNA targeting
Ting Tian et al.
Scientific Reports (2016)
A novel P2X4 receptor-selective antagonist produces anti-allodynic effect in a mouse model of herpetic pain
Yuta Matsumura et al.
SCIENTIFIC REPORTS (2016)
Purinergic regulation of the immune system
Caglar Cekic et al.
NATURE REVIEWS IMMUNOLOGY (2016)
The therapeutic agents that target ATP-sensitive potassium channels
Hussein N. Rubaiy
ACTA PHARMACEUTICA (2016)
Functional and therapeutic importance of purinergic signaling in polycystic kidney disease
Daria V. Ilatovskaya et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2016)
Calcium Channels and Associated Receptors in Malignant Brain Tumor Therapy
Fernanda B. Morrone et al.
MOLECULAR PHARMACOLOGY (2016)
Therapeutic innovation: Inflammatory-reactive astrocytes as targets of inflammation
Elisabeth Hansson et al.
IBRO REPORTS (2016)
New Drugs and Treatment Targets in Psoriasis
Kristian Kofoed et al.
ACTA DERMATO-VENEREOLOGICA (2015)
Targeting renal purinergic signalling for the treatment of lithium-induced nephrogenic diabetes insipidus
B. K. Kishore et al.
ACTA PHYSIOLOGICA (2015)
Adenosine 2A receptors in acute kidney injury
I. S. Vincent et al.
ACTA PHYSIOLOGICA (2015)
Adenosine A2a receptor stimulation prevents proteinuria in diabetic rats by promoting an anti-inflammatory phenotype without affecting oxidative stress
P. Persson et al.
ACTA PHYSIOLOGICA (2015)
Circulating adenosine levels are elevated in pregnant women with sickle cell disease through 2,3-DPG induction
Olaide Ashimi et al.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2015)
Enhancement of Muscle T Regulatory Cells and Improvement of Muscular Dystrophic Process in mdx Mice by Blockade of Extracellular ATP/P2X Axis
Elisabetta Gazzerro et al.
AMERICAN JOURNAL OF PATHOLOGY (2015)
P2X7 receptor inhibition protects against ischemic acute kidney injury in mice
Yanli Yan et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2015)
Silencing of MUC8 by siRNA increases P2Y2-induced airway inflammation
Hee-Jae Cha et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2015)
Mechanisms of C-peptide-mediated rescue of low O2-induced ATP release from erythrocytes of humans with Type 2 diabetes
Jennifer P. Richards et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2015)
Adenosine: an endogenous mediator in the pathogenesis of psoriasis
Moira Festugato
ANAIS BRASILEIROS DE DERMATOLOGIA (2015)
Activation of Adenosine Monophosphate- activated Protein Kinase Suppresses Neuroinflammation and Ameliorates Bone Cancer Pain
Huayuan Song et al.
ANESTHESIOLOGY (2015)
P2X3 receptors and sensitization of autonomic reflexes
Anthony P. Ford et al.
AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL (2015)
Purinergic Signalling in the Reproductive System
George I. Gorodeski
AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL (2015)
Vascular and inflammatory actions of P2X receptors in renal injury
Amelia R. Howarth et al.
AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL (2015)
Purinergic signaling in the immune system
Francesco Di Virgilio et al.
AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL (2015)
The infarct-sparing effect of IB-MECA against myocardial ischemia/reperfusion injury in mice is mediated by sequential activation of adenosine A3 and A2A receptors
Yikui Tian et al.
BASIC RESEARCH IN CARDIOLOGY (2015)
A novel cognitive impairment mechanism that astrocytic p-connexin 43 promotes neuronic autophagy via activation of P2X7R and down-regulation of GLT-1 expression in the hippocampus following traumatic brain injury in rats
Liqian Sun et al.
BEHAVIOURAL BRAIN RESEARCH (2015)
Blockade and reversal of spinal morphine tolerance by P2X3 receptor antagonist
Xiaqing Ma et al.
BEHAVIOURAL PHARMACOLOGY (2015)
Expression of adenosine receptors in monocytes from patients with bronchial asthma
Ksenia Yuryeva et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)
P2Y purinergic receptor-regulated insulin secretion is mediated by a cAMP/Epac/Kv channel pathway
Yi Zhang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)
Nucleotide modulates odor response through activation of purinergic receptor in olfactory sensory neuron
Yiqun Yu
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)
ATP stimulates pannexin 1 internalization to endosomal compartments
Andrew K. J. Boyce et al.
BIOCHEMICAL JOURNAL (2015)
Role of P2X7 receptor in Clostridium perfringens beta-toxin-mediated cellular injury
Masahiro Nagahama et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2015)
Nucleotide receptors control IL-8/CXCL8 and MCP-1/CCL2 secretions as well as proliferation in human glioma cells
Elizandra Braganhol et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2015)
Deletion of Adenosine A2A Receptors From Astrocytes Disrupts Glutamate Homeostasis Leading to Psychomotor and Cognitive Impairment: Relevance to Schizophrenia
Marco Matos et al.
BIOLOGICAL PSYCHIATRY (2015)
Novel, potent, orally bioavailable and selective mycobacterial ATP synthase inhibitors that demonstrated activity against both replicating and non-replicating M. tuberculosis
Supriya Singh et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2015)
Effect of Uncaria tomentosa extract on purinergic enzyme activities in lymphocytes of rats submitted to experimental adjuvant arthritis model
Lvia G. Castilhos et al.
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE (2015)
Extracellular ATP enhances radiation-induced brain injury through microglial activation and paracrine signaling via P2X7 receptor
Pengfei Xu et al.
BRAIN BEHAVIOR AND IMMUNITY (2015)
Role of mitochondrial ATP-sensitive potassium channel-mediated PKC-ε in delayed protection against myocardial ischemia/reperfusion injury in isolated hearts of sevoflurane-preconditioned rats
C. Wang et al.
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH (2015)
Constrictor prostanoids and uridine adenosine tetraphosphate: vascular mediators and therapeutic targets in hypertension and diabetes
Takayuki Matsumoto et al.
BRITISH JOURNAL OF PHARMACOLOGY (2015)
The expression of P2X7 receptors in EPCs and their potential role in the targeting of EPCs to brain gliomas
Jingqin Fang et al.
CANCER BIOLOGY & THERAPY (2015)
Genetic and Pharmacological Inactivation of the Purinergic P2RX7 Receptor Dampens Inflammation but Increases Tumor Incidence in a Mouse Model of Colitis-Associated Cancer
Paul Hofman et al.
CANCER RESEARCH (2015)
P2X7 receptor predicts postoperative cancer-specific survival of patients with clear-cell renal cell carcinoma
Zheng Liu et al.
CANCER SCIENCE (2015)
Impact of Intracoronary Adenosine on Myonecrosis in Patients with Unstable Angina Pectoris Undergoing Percutaneous Coronary Intervention
Filiz Kizilirmak et al.
CARDIOVASCULAR DRUGS AND THERAPY (2015)
Calcium signaling and the novel anti-proliferative effect of the UTP-sensitive P2Y11 receptor in rat cardiac myofibroblasts
Mariana Certal et al.
CELL CALCIUM (2015)
The Search for New Agonists to P2X7R for Clinical Use: Tuberculosis as a Possible Target
Romulo J. Soares-Bezerra et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2015)
Effects of Aerosolized Adenosine 5′-Triphosphate in Smokers and Patients With COPD
Ozen K. Basoglu et al.
CHEST (2015)
Aberrant Circulating Levels of Purinergic Signaling Markers Are Associated With Several Key Aspects of Peripheral Atherosclerosis and Thrombosis
Juho Jalkanen et al.
CIRCULATION RESEARCH (2015)
Ventricular Tachycardia Mechanistic Insights Derived From Adenosine
Bruce B. Lerman
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY (2015)
P2X Receptors and Diabetes
Carmen Fotino et al.
CURRENT MEDICINAL CHEMISTRY (2015)
Physiopathological Roles of P2X Receptors in the Central Nervous System
G. Burnstock
CURRENT MEDICINAL CHEMISTRY (2015)
P2X Receptors and Inflammation
Francesco Virgilio
CURRENT MEDICINAL CHEMISTRY (2015)
The Role of P2X Receptors in Bone Biology
N. R. Jorgensen et al.
CURRENT MEDICINAL CHEMISTRY (2015)
Involvement of the P2X7 Purinergic Receptor in Inflammation: An Update of Antagonists Series Since 2009 and their Promising Therapeutic Potential
Davy Baudelet et al.
CURRENT MEDICINAL CHEMISTRY (2015)
P2X Receptors in the Cardiovascular System and their Potential as Therapeutic Targets in Disease
Vera Ralevic
CURRENT MEDICINAL CHEMISTRY (2015)
Purinergic Signaling and Energy Homeostasis in Psychiatric Disorders
D. Lindberg et al.
CURRENT MOLECULAR MEDICINE (2015)
Platelet Inhibition Agents: Current and Future P2Y12 Receptor Antagonists
Jie Tang et al.
CURRENT VASCULAR PHARMACOLOGY (2015)
CD73 Predicts Favorable Prognosis in Patients with Nonmuscle-Invasive Urothelial Bladder Cancer
Marian S. Wettstein et al.
DISEASE MARKERS (2015)
One drug, two outcomes after atrial fibrillation ablation: the situational irony of adenosine
T. Jared Bunch
EUROPEAN HEART JOURNAL (2015)
Prokineticin 2 facilitates mechanical allodynia induced by α, β-methylene ATP in rats
Cuixia Ren et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2015)
P2X7 receptor antagonist activity of the anti-allergic agent oxatomide
Kazuki Yoshida et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2015)
The adenosine A2A receptor antagonist, istradefylline enhances the anti-parkinsonian activity of low doses of dopamine agonists in MPTP-treated common marmosets
Shin-ichi Uchida et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2015)
P2X7 receptor antagonists protect against N-methyl-D-aspartic acid-induced neuronal injury in the rat retina
Kenji Sakamoto et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2015)
Adenosine A2B receptor stimulates angiogenesis by inducing VEGF and eNOS in human microvascular endothelial cells
Xiaolong Du et al.
EXPERIMENTAL BIOLOGY AND MEDICINE (2015)
Diadenosine tetraphosphate improves adrenergic anti-glaucomatous drug delivery and efficiency
Patricia Loma et al.
EXPERIMENTAL EYE RESEARCH (2015)
Suppression of adenosine 2a receptor (A2aR)-mediated adenosine signaling improves disease phenotypes in a mouse model of amyotrophic lateral sclerosis
Seng Kah Ng et al.
EXPERIMENTAL NEUROLOGY (2015)
Neuronal KATP channels mediate hypoxic preconditioning and reduce subsequent neonatal hypoxic-ischemic brain injury
Hong-Shuo Sun et al.
EXPERIMENTAL NEUROLOGY (2015)
P2Y12 receptor inhibitors for secondary prevention of ischemic stroke
Fang Liu et al.
EXPERT OPINION ON PHARMACOTHERAPY (2015)
The efficacy of oral adenosine A2A antagonist istradefylline for the treatment of moderate to severe Parkinson's disease
Ruxandra Julia Vorovenci et al.
EXPERT REVIEW OF NEUROTHERAPEUTICS (2015)
Extracellular ATP protects against sepsis through macrophage P2X7 purinergic receptors by enhancing intracellular bacterial killing
Balazs Csoka et al.
FASEB JOURNAL (2015)
Selective permeabilization of cervical cancer cells to an ionic DNA-binding cytotoxin by activation of P2Y receptors
Maurish Bukhari et al.
FEBS LETTERS (2015)
Prenatal Exposure to Inflammatory Conditions Increases Cx43 and Panx1 Unopposed Channel Opening and Activation of Astrocytes in the Offspring Effect on Neuronal Survival
Beatriz C. Avendano et al.
GLIA (2015)
P2Y2 Receptor Antagonists as Anti-Allodynic Agents in Acute and Sub-Chronic Trigeminal Sensitization: Role of Satellite Glial Cells
Giulia Magni et al.
GLIA (2015)
A rare P2X7 variant Arg307Gln with absent pore formation function protects against neuroinflammation in multiple sclerosis
Ben J. Gu et al.
HUMAN MOLECULAR GENETICS (2015)
Promotion of Wound Healing by an Agonist of Adenosine A2A Receptor Is Dependent on Tissue Plasminogen Activator
M. Carmen Montesinos et al.
INFLAMMATION (2015)
P2X7 Receptor Expression in Peripheral Blood Monocytes Is Correlated With Plasma C-Reactive Protein and Cytokine Levels in Patients With Type 2 Diabetes Mellitus: a Preliminary Report
Hong Wu et al.
INFLAMMATION (2015)
Safety and Efficacy of an Oral Inhibitor of the Purinergic Receptor P2X7 in Adult Patients with Moderately to Severely Active Crohn's Disease: A Randomized Placebo-controlled, Double-blind, Phase IIa Study
Alexander Eser et al.
INFLAMMATORY BOWEL DISEASES (2015)
P2X7 receptor as predictor gene for glioma radiosensitivity and median survival
Marina P. Gehring et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2015)
The use of adenosine and adenosine triphosphate testing in the diagnosis, risk stratification and management of patients with syncope: Current evidence and future perspectives
Nikolaos Fragakis et al.
INTERNATIONAL JOURNAL OF CARDIOLOGY (2015)
Opiorphin-dependent upregulation of CD73 (a key enzyme in the adenosine signaling pathway) in corporal smooth muscle cells exposed to hypoxic conditions and in corporal tissue in pre-priapic sickle cell mice
S. Fu et al.
INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH (2015)
Nucleotide Salvage Deficiencies, DNA Damage and Neurodegeneration
Michael Fasullo et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)
Limitation of Infarct Size and No-Reflow by Intracoronary Adenosine Depends Critically on Dose and Duration
Tuncay Yetgin et al.
JACC-CARDIOVASCULAR INTERVENTIONS (2015)
Increased uric acid levels in bipolar disorder subjects during different phases of illness
Umberto Albert et al.
JOURNAL OF AFFECTIVE DISORDERS (2015)
Beneficial and detrimental role of adenosine signaling in diseases and therapy
Hong Liu et al.
JOURNAL OF APPLIED PHYSIOLOGY (2015)
A2 Adenosine Receptor-mediated Cardioprotection Against Reperfusion Injury in Rat Hearts Is Associated With Autophagy Downregulation
Jianjuan Ke et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2015)
Involvement of Purinergic System in the Release of Cytokines by Macrophages Exposed to Glioma-Conditioned Medium
Leticia Scussel Bergamin et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2015)
Involvement of a P2X7 Receptor in the Acrosome Reaction Induced by ATP in Rat Spermatozoa
Jorge L. Torres-Fuentes et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2015)
Blockade of P2X7 receptors or pannexin-1 channels similarly attenuates postischemic damage
Abraham Cisneros-Mejorado et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2015)
External Dentin Stimulation Induces ATP Release in Human Teeth
X. Liu et al.
JOURNAL OF DENTAL RESEARCH (2015)
Alveolar Epithelial A2B Adenosine Receptors in Pulmonary Protection during Acute Lung Injury
Sandra Hoegl et al.
JOURNAL OF IMMUNOLOGY (2015)
Human β Defensin-3 Increases CD86 Expression on Monocytes by Activating the ATP-Gated Channel P2X7
Anthony B. Lioi et al.
JOURNAL OF IMMUNOLOGY (2015)
Loss of Mouse P2Y4 Nucleotide Receptor Protects against Myocardial Infarction through Endothelin-1 Downregulation
Michael Horckmans et al.
JOURNAL OF IMMUNOLOGY (2015)
The P2X7 Receptor Contributes to the Development of the Exacerbated Inflammatory Response Associated with Sepsis
Patricia Texeira Santana et al.
JOURNAL OF INNATE IMMUNITY (2015)
Metabolic danger signals, uric acid and ATP, mediate inflammatory cross-talk between hepatocytes and immune cells in alcoholic liver disease
Jan Petrasek et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2015)
P2X7 receptors: role in bone cell formation and function
Ankita Agrawal et al.
JOURNAL OF MOLECULAR ENDOCRINOLOGY (2015)
Critical Contribution of Adenosine A2A Receptors in Bone Marrow-Derived Cells to White Matter Lesions Induced by Chronic Cerebral Hypoperfusion
Hong Ran et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2015)
Upregulation of P2RX7 in Cx3cr1-Deficient Mononuclear Phagocytes Leads to Increased Interleukin-1β Secretion and Photoreceptor Neurodegeneration
Shulong J. Hu et al.
JOURNAL OF NEUROSCIENCE (2015)
Postsynaptic P2X3-containing receptors in gustatory nerve fibres mediate responses to all taste qualities in mice
Aurelie Vandenbeuch et al.
JOURNAL OF PHYSIOLOGY-LONDON (2015)
Possible role of pannexin 1/P2x7 purinoceptor in neuroprotective mechanism of ischemic postconditioning in mice
Namarta Mahi et al.
JOURNAL OF SURGICAL RESEARCH (2015)
P2Y12 Receptor Localizes in the Renal Collecting Duct and Its Blockade Augments Arginine Vasopressin Action and Alleviates Nephrogenic Diabetes Insipidus
Yue Zhang et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2015)
Rhinoviral stimuli, epithelial factors and ATP signalling contribute to bronchial smooth muscle production of IL-33
Jenny Calven et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2015)
Extracellular Uridine Triphosphate and Adenosine Triphosphate Attenuate Endothelial Inflammation through miR-22-Mediated ICAM-1 Inhibition
Olof Gidlof et al.
JOURNAL OF VASCULAR RESEARCH (2015)
Adenosine-guided pulmonary vein isolation for the treatment of paroxysmal atrial fibrillation: an international, multicentre, randomised superiority trial
Laurent Macle et al.
LANCET (2015)
P2X3 receptor antagonist (AF-219) in refractory chronic cough: a randomised, double-blind, placebo-controlled phase 2 study
Rayid Abdulqawi et al.
LANCET (2015)
Deficits in Endogenous Adenosine Formation by Ecto-5 '-Nucleotidase/CD73 Impair Neuromuscular Transmission and Immune Competence in Experimental Autoimmune Myasthenia Gravis
Laura Oliveira et al.
MEDIATORS OF INFLAMMATION (2015)
Pathophysiological Role of Extracellular Purinergic Mediators in the Control of Intestinal Inflammation
Yosuke Kurashima et al.
MEDIATORS OF INFLAMMATION (2015)
Decrease of serum adenine nucleotide hydrolysis in an irritant contact dermatitis mice model: potential P2X7R involvement
R. F. Zanin et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2015)
Extracellular nucleotides as novel, underappreciated pro-metastatic factors that stimulate purinergic signaling in human lung cancer cells
Gabriela Schneider et al.
MOLECULAR CANCER (2015)
Adenosine signalling in diabetes mellitus-pathophysiology and therapeutic considerations
Luca Antonioli et al.
NATURE REVIEWS ENDOCRINOLOGY (2015)
Purinergic signalling in neuroregeneration
Geoffrey Burnstock
NEURAL REGENERATION RESEARCH (2015)
Extracellular ATP induces intracellular alpha-synuclein accumulation via P2X1 receptor-mediated lysosomal dysfunction
Ming Gan et al.
NEUROBIOLOGY OF AGING (2015)
Preconditioning with latrepirdine, an adenosine 5′-monophosphate-activated protein kinase activator, delays amyotrophic lateral sclerosis progression in SOD1G93A mice
Karen S. Coughlan et al.
NEUROBIOLOGY OF AGING (2015)
Targeting P2X7 receptor for the treatment of central post-stroke pain in a rodent model
Yung-Hui Kuan et al.
NEUROBIOLOGY OF DISEASE (2015)
Inactivation of adenosine A2A receptors reverses working memory deficits at early stages of Huntington's disease models
Wei Li et al.
NEUROBIOLOGY OF DISEASE (2015)
Neuropharmacology of purinergic receptors in human submucous plexus: Involvement of P2X1, P2X2, P2X3 channels, P2Y and A3 metabotropic receptors in neurotransmission
A. Lifian-Rico et al.
NEUROPHARMACOLOGY (2015)
Role of adenosine receptor subtypes in methamphetamine reward and reinforcement
Kevin A. Kavanagh et al.
NEUROPHARMACOLOGY (2015)
CENTRAL OR PERIPHERAL DELIVERY OF AN ADENOSINE A1 RECEPTOR AGONIST IMPROVES MECHANICAL ALLODYNIA IN A MOUSE MODEL OF PAINFUL DIABETIC NEUROPATHY
N. K. Katz et al.
NEUROSCIENCE (2015)
HOMOCYSTEINE-INDUCED ATTENUATION OF VASCULAR ENDOTHELIUM-DEPENDENT HYPERALGESIA IN THE RAT
E. K. Joseph et al.
NEUROSCIENCE (2015)
DOPAMINE MIDBRAIN NEURONS IN HEALTH AND PARKINSON'S DISEASE: EMERGING ROLES OF VOLTAGE-GATED CALCIUM CHANNELS AND ATP-SENSITIVE POTASSIUM CHANNELS
E. Dragicevic et al.
NEUROSCIENCE (2015)
P2X7 RECEPTOR-MEDIATED ANALGESIA IN CANCER-INDUCED BONE PAIN
S. Falk et al.
NEUROSCIENCE (2015)
Microglial P2X7 receptor in the hypothalamic paraventricular nuclei contributes to sympathoexcitatory responses in acute myocardial infarction rat
Dongshu Du et al.
NEUROSCIENCE LETTERS (2015)
The P2X7 receptor is a key modulator of the PI3K/GSK3β/VEGF signaling network: evidence in experimental neuroblastoma
F. Amoroso et al.
ONCOGENE (2015)
P2Y2 nucleotide receptor-mediated extracellular signal-regulated kinases and protein kinase C activation induces the invasion of highly metastatic breast cancer cells
So Young Eun et al.
ONCOLOGY REPORTS (2015)
P2X7 receptor stimulates breast cancer cell invasion and migration via the AKT pathway
Jiyi Xia et al.
ONCOLOGY REPORTS (2015)
Adenosine receptors and diabetes: Focus on the A2B adenosine receptor subtype
Stefania Merighi et al.
PHARMACOLOGICAL RESEARCH (2015)
Interactions of pannexin 1 with NMDA and P2X7 receptors in central nervous system pathologies: Possible role on chronic pain
D. Bravo et al.
PHARMACOLOGICAL RESEARCH (2015)
Placental expression of adenosine A2A receptor and hypoxia inducible factor-1 alpha in early pregnancy, term and pre-eclamptic pregnancies: Interactions with placental renin-angiotensin system
L. O. Kurlak et al.
PLACENTA (2015)
In vitro Study of a Novel Stent Coating Using Modified CD39 Messenger RNA to Potentially Reduce Stent Angioplasty-Associated Complications
Meike-Kristin Abraham et al.
PLOS ONE (2015)
Caffeine acts through neuronal adenosine A2A receptors to prevent mood and memory dysfunction triggered by chronic stress
Manuella P. Kaster et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Purinergic system dysfunction in mood disorders: a key target for developing improved therapeutics
Robin Ortiz et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2015)
Serum uric acid levels and different phases of illness in bipolar I patients treated with lithium
Matteo Muti et al.
PSYCHIATRY RESEARCH (2015)
The role of purinergic signaling in the etiology of migraine and novel antimigraine treatment
Marek Cieslak et al.
PURINERGIC SIGNALLING (2015)
The role of P2X7 receptors in tissue fibrosis: a brief review
Daniela Gentile et al.
PURINERGIC SIGNALLING (2015)
Potentiation of temozolomide antitumor effect by purine receptor ligands able to restrain the in vitro growth of human glioblastoma stem cells
Iolanda D'Alimonte et al.
PURINERGIC SIGNALLING (2015)
Blood cells: an historical account of the roles of purinergic signalling
Geoffrey Burnstock
PURINERGIC SIGNALLING (2015)
Supportive or detrimental roles of P2Y receptors in brain pathology?-The two faces of P2Y receptors in stroke and neurodegeneration detected in neural cell and in animal model studies
Daniel Foerster et al.
PURINERGIC SIGNALLING (2015)
Presymptomatic and symptomatic ALS SOD1(G93A) mice differ in adenosine A1 and A2A receptor-mediated tonic modulation of neuromuscular transmission
Filipe Nascimento et al.
PURINERGIC SIGNALLING (2015)
Creatine, similarly to ketamine, affords antidepressant-like effects in the tail suspension test via adenosine A1 and A2A receptor activation
Mauricio P. Cunha et al.
PURINERGIC SIGNALLING (2015)
A2B Adenosine Receptor Agonist Improves Erectile Function in Diabetic Rats
Jiaming Wen et al.
TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE (2015)
Purinergic signaling in atherosclerosis
Davide Ferrari et al.
TRENDS IN MOLECULAR MEDICINE (2015)
High expression of CD39/ENTPD1 in malignant epithelial cells of human rectal adenocarcinoma
Bin Zhang et al.
TUMOR BIOLOGY (2015)
P2X3 purinergic receptor overexpression is associated with poor recurrence-free survival in hepatocellular carcinoma patients
Janielle P. Maynard et al.
ONCOTARGET (2015)
PI3K/Akt signaling pathway triggers P2X7 receptor expression as a pro-survival factor of neuroblastoma cells under limiting growth conditions
Rosa Gomez-Villafuertes et al.
SCIENTIFIC REPORTS (2015)
microRNA targeting of the P2X7 purinoceptor opposes a contralateral epileptogenic focus in the hippocampus
Eva M. Jimenez-Mateos et al.
SCIENTIFIC REPORTS (2015)
P2x7 purinergic signaling in dilated cardiomyopathy induced by auto-immunity against muscarinic M2 receptors: autoantibody levels, heart functionality and cytokine expression
Camila Guerra Martinez et al.
SCIENTIFIC REPORTS (2015)
P2RX7 Purinoceptor: A Therapeutic Target for Ameliorating the Symptoms of Duchenne Muscular Dystrophy
Anthony Sinadinos et al.
PLOS MEDICINE (2015)
Extracellular Adenosine Protects against Streptococcus pneumoniae Lung Infection by Regulating Pulmonary Neutrophil Recruitment
Elsa N. Bou Ghanem et al.
PLOS PATHOGENS (2015)
The efficacy of oral adenosine A2A antagonist istradefylline for the treatment of moderate to severe Parkinson's disease
Ruxandra Julia Vorovenci et al.
EXPERT REVIEW OF NEUROTHERAPEUTICS (2015)
Antipurinergic therapy corrects the autism-like features in the Fragile X (Fmr1 knockout) mouse model
Jane C. Naviaux et al.
MOLECULAR AUTISM (2015)
ATP as a multi-target danger signal in the brain
Ricardo J. Rodrigues et al.
FRONTIERS IN NEUROSCIENCE (2015)
Neuroprotection Mediated by P2Y13 Nucleotide Receptors in Neurons
Raquel Perez-Sen et al.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2015)
Role of P2X7 and P2Y2 receptors on α-secretase-dependent APP processing: Control of amyloid plaques formation in vivo by P2X7 receptor
M. Teresa Miras-Portugal et al.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2015)
Purinergic control of inflammation and thrombosis: Role of P2X1 receptors
Cecile Oury et al.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2015)
Effects of intracavernous injection of P2X3 and NK1 receptor antagonists on erectile dysfunction induced by spinal cord transection in rats
C. -L. Li et al.
ANDROLOGIA (2015)
P2Y receptors in Alzheimer's disease
Laurie Erb et al.
BIOLOGY OF THE CELL (2015)
Accelerated Tumor Progression in Mice Lacking the ATP Receptor P2X7
Elena Adinolfi et al.
CANCER RESEARCH (2015)
The ADP Antagonist MRS2179 Regulates the Phenotype of Smooth Muscle Cells to Limit Intimal Hyperplasia
Rong Liu et al.
CARDIOVASCULAR DRUGS AND THERAPY (2015)
Efficacy of Adenosine A2A Receptor Antagonist Istradefylline as Augmentation for Parkinson's Disease: A Meta-analysis of Randomized Controlled Trials
Yingqun Tao et al.
CELL BIOCHEMISTRY AND BIOPHYSICS (2015)
ATP Signaling in Brain: Release, Excitotoxicity and Potential Therapeutic Targets
Abraham Cisneros-Mejorado et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2015)
Su1599 The Selective Adenosine 2B Receptor Antagonist MRS1754 Mitigates Hepatic Collagen Deposition During Fibrosis Progression and Induces Mild Fibrosis Regression
Matthias Stoll et al.
GASTROENTEROLOGY (2015)
A P2X7 receptor antagonist attenuates experimental autoimmune myocarditis via suppressed myocardial CD4+ T and macrophage infiltration and NADPH oxidase 2/4 expression in mice
Hirofumi Zempo et al.
HEART AND VESSELS (2015)
Differential effects of experimental ulcerative colitis on P2X7 receptor expression in enteric neurons
Marcos Vinicius da Silva et al.
HISTOCHEMISTRY AND CELL BIOLOGY (2015)
Adenosine protects Sprague Dawley rats from high-fat diet and repeated acute restraint stress-induced intestinal inflammation and altered expression of nutrient transporters
C. Y. Lee
JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION (2015)
Expression of a Second Ecto-5'-Nucleotidase Variant Besides the Usual Protein in Symptomatic Phase of Experimental Autoimmune Encephalomyelitis
Irena Lavrnja et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2015)
Contributions of purinergic P2X3 receptors within the midbrain periaqueductal gray to diabetes-induced neuropathic pain
Jianfei Guo et al.
JOURNAL OF PHYSIOLOGICAL SCIENCES (2015)
Odontoblasts as sensory receptors: transient receptor potential channels, pannexin-1, and ionotropic ATP receptors mediate intercellular odontoblast-neuron signal transduction
Yoshiyuki Shibukawa et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2015)
Purinergic signalling is required for calcium oscillations in migratory chondrogenic progenitor cells
Csaba Matta et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2015)
P2X3 Receptors Mediate Visceral Hypersensitivity during Acute Chemically-Induced Colitis and in the Post-Inflammatory Phase via Different Mechanisms of Sensitization
Annemie Deiteren et al.
PLOS ONE (2015)
Ocular Hypotensive Effects of the ATP-Sensitive Potassium Channel Opener Cromakalim in Human and Murine Experimental Model Systems
Uttio Roy Chowdhury et al.
PLOS ONE (2015)
P2X7 receptor of rat dorsal root ganglia is involved in the effect of moxibustion on visceral hyperalgesia
Shuangmei Liu et al.
PURINERGIC SIGNALLING (2015)
Purine receptors are required for DHA-mediated neuroprotection against oxygen and glucose deprivation in hippocampal slices
Simone Molz et al.
PURINERGIC SIGNALLING (2015)
Cardiac purinergic signalling in health and disease
Geoffrey Burnstock et al.
PURINERGIC SIGNALLING (2015)
Physiological Electrical Signals Promote Chain Migration of Neuroblasts by Up-Regulating P2Y1 Purinergic Receptors and Enhancing Cell Adhesion
Lin Cao et al.
STEM CELL REVIEWS AND REPORTS (2015)
Caffeine, Through Adenosine A3 Receptor-Mediated Actions, Suppresses Amyloid-β Protein Precursor Internalization and Amyloid-β Generation
Shanshan Li et al.
JOURNAL OF ALZHEIMERS DISEASE (2015)
Rat, Mouse, and Primate Models of Chronic Glaucoma Show Sustained Elevation of Extracellular ATP and Altered Purinergic Signaling in the Posterior Eye
Wennan Lu et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2015)
BRAIN INJURY ALTERS ECTONUCLEOTIDASE ACTIVITIES AND ADENINE NUCLEOTIDE LEVELS IN RAT SERUM
Danijela Laketa et al.
JOURNAL OF MEDICAL BIOCHEMISTRY (2015)
Elevated Placental Adenosine Signaling Contributes to the Pathogenesis of Preeclampsia
Takayuki Iriyama et al.
CIRCULATION (2015)
The A3 Adenosine Receptor: History and Perspectives
Pier Andrea Borea et al.
PHARMACOLOGICAL REVIEWS (2015)
Protective effects of the novel adenosine derivative WS0701 in a mouse model of posttraumatic stress disorder
Zhong-lin Huang et al.
ACTA PHARMACOLOGICA SINICA (2014)
Extracellular Adenosine Triphosphate Affects Systemic and Kidney Immune Cell Populations in Pregnant Rats
Floor Spaans et al.
AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY (2014)
Inhibition of the Purinergic Pathway Prolongs Mouse Lung Allograft Survival
Kaifeng Liu et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2014)
Activation of P2RY11 and ATP Release by Lipoxin A4 Restores the Airway Surface Liquid Layer and Epithelial Repair in Cystic Fibrosis
Gerard Higgins et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2014)
EXPRESSION OF MAJOR ECTONUCLEOTIDASES AFTER CORTICAL STAB BRAIN INJURY IN RATS: A REAL-TIME PCR STUDY
Ana Parabucki et al.
ARCHIVES OF BIOLOGICAL SCIENCES (2014)
Neural regulation of inflammation in the airways and lungs
Alice E. McGovern et al.
AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL (2014)
Ectonucleotidase expression profile and activity in human cervical cancer cell lines
Aline Beckenkamp et al.
BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE (2014)
Regulation of Fear Responses by Striatal and Extrastriatal Adenosine A2A Receptors in Forebrain
Catherine J. Wei et al.
BIOLOGICAL PSYCHIATRY (2014)
Putative roles of purinergic signaling in human immunodeficiency virus-1 infection
Paulo A. F. Pacheco et al.
BIOLOGY DIRECT (2014)
Adenosine through the A2A adenosine receptor increases IL-1β in the brain contributing to anxiety
Gabriel S. Chiu et al.
BRAIN BEHAVIOR AND IMMUNITY (2014)
Role of ATP-sensitive potassium channels in modulating nociception in rat model of bone cancer pain
Hui Xia et al.
BRAIN RESEARCH (2014)
Purinergic neuromuscular transmission in the gastrointestinal tract; functional basis for future clinical and pharmacological studies
Marcel Jimenez et al.
BRITISH JOURNAL OF PHARMACOLOGY (2014)
Ion channels of the mammalian urethra
Barry D. Kyle
CHANNELS (2014)
Adenosine A2A Receptor Antagonists in Parkinson's Disease: Progress in Clinical Trials from the Newly Approved Istradefylline to Drugs in Early Development and Those Already Discontinued
Annalisa Pinna
CNS DRUGS (2014)
From Mechanosensitivity to Inflammatory Responses: New Players in the Pathology of Glaucoma
David Krizaj et al.
CURRENT EYE RESEARCH (2014)
The Dopamine D2 and Adenosine A2A Receptors: Past, Present and Future Trends for the Treatment of Parkinson’s Disease
M. Jorg et al.
CURRENT MEDICINAL CHEMISTRY (2014)
The elevated gene expression level of the A2B adenosine receptor is associated with hyperglycemia in women with gestational diabetes mellitus
Marzena Wojcik et al.
DIABETES-METABOLISM RESEARCH AND REVIEWS (2014)
Purinergic Signaling in Liver Disease
Byron P. Vaughn et al.
DIGESTIVE DISEASES (2014)
Spinal cord pathology is ameliorated by P2X7 antagonism in a SOD1-mutant mouse model of amyotrophic lateral sclerosis
Savina Apolloni et al.
DISEASE MODELS & MECHANISMS (2014)
Adenosine and inflammation: what's new on the horizon?
Luca Antonioli et al.
DRUG DISCOVERY TODAY (2014)
The complex P2X7 receptor/inflammasome in perivascular fat tissue of heavy smokers
Chiara Rossi et al.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2014)
Extracellular adenosine controls NKT-cell-dependent hepatitis induction
Meenakshi Subramanian et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2014)
Protective effects of phosphodiesterase-1 (PDE1) and ATP sensitive potassium (KATP) channel modulators against 3-nitropropionic acid induced behavioral and biochemical toxicities in experimental Huntington's disease
Surbhi Gupta et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2014)
P2Y2R activation by nucleotides promotes skin wound-healing process
Hana Jin et al.
EXPERIMENTAL DERMATOLOGY (2014)
Purines in the eye: Recent evidence for the physiological and pathological role of purines in the RPE, retinal neurons, astrocytes, Muller cells, lens, trabecular meshwork, cornea and lacrimal gland
Julie Sanderson et al.
EXPERIMENTAL EYE RESEARCH (2014)
Newer targets for modulation of intraocular pressure: focus on adenosine receptor signaling pathways
Renu Agarwal et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2014)
White Matter Injury: Ischemic and Nonischemic
Robert F. Fern et al.
GLIA (2014)
Potential for Developing Purinergic Drugs for Gastrointestinal Diseases
Fernando Ochoa-Cortes et al.
INFLAMMATORY BOWEL DISEASES (2014)
Overexpression of ATP-activated P2X7 Receptors in the Intestinal Mucosa Is Implicated in the Pathogenesis of Crohn's Disease
Adriane R. Neves et al.
INFLAMMATORY BOWEL DISEASES (2014)
Non-Synonymous Single Nucleotide Polymorphisms in the P2X Receptor Genes: Association with Diseases, Impact on Receptor Functions and Potential Use as Diagnosis Biomarkers
Emily A. Caseley et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2014)
P2X and P2Y Receptors-Role in the Pathophysiology of the Nervous System
Kamila Puchalowicz et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2014)
Adenosine Physiology, Pharmacology, and Clinical Applications
Jamie Layland et al.
JACC-CARDIOVASCULAR INTERVENTIONS (2014)
The P2Y2 Nucleotide Receptor Mediates the Proliferation and Migration of Human Hepatocellular Carcinoma Cells Induced by ATP
Rui Xie et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Paracrine Stimulation of P2X7 Receptor by ATP Activates a Proliferative Pathway in Ovarian Carcinoma Cells
Francisco G. Vazquez-Cuevas et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2014)
The Effect of PDRN, an Adenosine Receptor A2A Agonist, on the Healing of Chronic Diabetic Foot Ulcers: Results of a Clinical Trial
Francesco Squadrito et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2014)
Effect of genetic deletion and pharmacological antagonism of P2X7 receptors in a mouse animal model of migraine
Flora Goeloencser et al.
JOURNAL OF HEADACHE AND PAIN (2014)
Leukotriene B4 Modulates P2X7 Receptor-Mediated Leishmania amazonensis Elimination in Murine Macrophages
Mariana M. Chaves et al.
JOURNAL OF IMMUNOLOGY (2014)
Adenosine A2A Receptor as a Drug Discovery Target
Manuel de Lera Ruiz et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Neuronal Hyperactivity Recruits Microglial Processes via Neuronal NMDA Receptors and Microglial P2Y12 Receptors after Status Epilepticus
Ukpong B. Eyo et al.
JOURNAL OF NEUROSCIENCE (2014)
PKA-independent cAMP stimulation of white adipocyte exocytosis and adipokine secretion: modulations by Ca2+ and ATP
Ali M. Komai et al.
JOURNAL OF PHYSIOLOGY-LONDON (2014)
CD73-Dependent Generation of Adenosine and Endothelial Adora2b Signaling Attenuate Diabetic Nephropathy
Eunyoung Tak et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2014)
Gain and loss of function of P2X7 receptors: mechanisms, pharmacology and relevance to diabetic neuropathic pain
Daniel Ursu et al.
MOLECULAR PAIN (2014)
Adenosine activates brown adipose tissue and recruits beige adipocytes via A2A receptors
Thorsten Gnad et al.
NATURE (2014)
Exaggerated renal fibrosis in P2X4 receptor-deficient mice following unilateral ureteric obstruction
Min Jeong Kim et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2014)
Adenosine A2A Receptors Modulate Acute Injury and Neuroinflammation in Brain Ischemia
Felicita Pedata et al.
MEDIATORS OF INFLAMMATION (2014)
Purinergic Receptors in Ocular Inflammation
Ana Guzman-Aranguez et al.
MEDIATORS OF INFLAMMATION (2014)
Role of Microglia Adenosine A(2A) Receptors in Retinal and Brain Neurodegenerative Diseases
Ana R. Santiago et al.
MEDIATORS OF INFLAMMATION (2014)
Expression, pharmacology and functional activity of adenosine A1 receptors in genetic models of Huntington's disease
Antonella Ferrante et al.
NEUROBIOLOGY OF DISEASE (2014)
P2X4 receptors expressed on microglial cells in post-ischemic inflammation of brain ischemic injury
Rui-dong Cheng et al.
NEUROCHEMISTRY INTERNATIONAL (2014)
Blockade of peripheral P2Y1 receptors prevents the induction of thermal hyperalgesia via modulation of TRPV1 expression in carrageenan-induced inflammatory pain rats: Involvement of p38 MAPK phosphorylation in DRGs
Soon-Gu Kwon et al.
NEUROPHARMACOLOGY (2014)
Adenosine (A)2A receptor modulation of nicotine-induced locomotor sensitization. A pharmacological and transgenic approach
Joanna Jastrzebska et al.
NEUROPHARMACOLOGY (2014)
Presynaptic adenosine A1 receptors modulate excitatory transmission in the rat basolateral amygdala
Andrew R. Rau et al.
NEUROPHARMACOLOGY (2014)
LPS-induced dental pulp inflammation increases expression of ionotropic purinergic receptors in rat trigeminal ganglion
Yangxi Chen et al.
NEUROREPORT (2014)
PURINERGIC SIGNALING NEGATIVELY REGULATES ACTIVITY OF AN OLFACTORY RECEPTOR IN AN ODORANT-DEPENDENT MANNER
Y. Yu et al.
NEUROSCIENCE (2014)
A HYPEREXCITABILITY PHENOTYPE IN MOUSE TRIGEMINAL SENSORY NEURONS EXPRESSING THE R192Q CACNA1A MISSENSE MUTATION OF FAMILIAL HEMIPLEGIC MIGRAINE TYPE-1
S. K. Hullugundi et al.
NEUROSCIENCE (2014)
Targets for Botulinum Toxin in the Lower Urinary Tract
Francisco Cruz
NEUROUROLOGY AND URODYNAMICS (2014)
Voltage- gated and ATP- sensitive K plus channels are associated with cell proliferation and tumorigenesis of human glioma
Qin Ru et al.
ONCOLOGY REPORTS (2014)
A mutation causing increased KATP channel activity leads to reduced anxiety in mice
Carolina Lahmann et al.
PHYSIOLOGY & BEHAVIOR (2014)
Extracellular ATP decreases trophoblast invasion, spiral artery remodeling and immune cells in the mesometrial triangle in pregnant rats
F. Spaans et al.
PLACENTA (2014)
Purinergic Signaling on Leukocytes Infiltrating the LPS-Injured Lung
Daniela Friebe et al.
PLOS ONE (2014)
P2X7 Receptor in the Kidneys of Diabetic Rats Submitted to Aerobic Training or to N-Acetylcysteine Supplementation
Adelson M. Rodrigues et al.
PLOS ONE (2014)
Expression and Characterization of Purinergic Receptors in Rat Middle Meningeal Artery-Potential Role in Migraine
Kristian Agmund Haanes et al.
PLOS ONE (2014)
P2Y6 Receptor-Mediated Proinflammatory Signaling in Human Bronchial Epithelia
Yuan Hao et al.
PLOS ONE (2014)
Trophic Activity of Human P2X7 Receptor Isoforms A and B in Osteosarcoma
Anna Lisa Giuliani et al.
PLOS ONE (2014)
Adenosine A2A Receptors Activation Facilitates Neuromuscular Transmission in the Pre-Symptomatic Phase of the SOD1(G93A) ALS Mice, but Not in the Symptomatic Phase
Filipe Nascimento et al.
PLOS ONE (2014)
Involvement of the P2X7 Purinergic Receptor in Colonic Motor Dysfunction Associated with Bowel Inflammation in Rats
Luca Antonioli et al.
PLOS ONE (2014)
P2X7 Receptor Modulates Inflammatory and Functional Pulmonary Changes Induced by Silica
Leonardo C. Moncao-Ribeiro et al.
PLOS ONE (2014)
Neurobiology of microglial action in CNS injuries: Receptor-mediated signaling mechanisms and functional roles
Xiaoming Hu et al.
PROGRESS IN NEUROBIOLOGY (2014)
Remyelination after spinal cord injury: Is it a target for repair?
Jason R. Plemel et al.
PROGRESS IN NEUROBIOLOGY (2014)
Purinergic signalling in the urinary tract in health and disease
Geoffrey Burnstock
PURINERGIC SIGNALLING (2014)
Purinergic signalling in endocrine organs
Geoffrey Burnstock
PURINERGIC SIGNALLING (2014)
Purinergic signalling in the reproductive system in health and disease
Geoffrey Burnstock
PURINERGIC SIGNALLING (2014)
Purinergic signalling in the liver in health and disease
Geoffrey Burnstock et al.
PURINERGIC SIGNALLING (2014)
Purinergic signalling in the kidney in health and disease
Geoffrey Burnstock et al.
PURINERGIC SIGNALLING (2014)
Loss of P2X7 nucleotide receptor function leads to abnormal fat distribution in mice
Kim L. Beaucage et al.
PURINERGIC SIGNALLING (2014)
Autocrine signaling via release of ATP and activation of P2X7 receptor influences motile activity of human lung cancer cells
Erina Takai et al.
PURINERGIC SIGNALLING (2014)
The P2X7 Receptor: A Key Player in Immune-Mediated Bone Loss?
Torben Madsen Kvist et al.
SCIENTIFIC WORLD JOURNAL (2014)
P2X7 receptor blockade protects against cisplatin-induced nephrotoxicity in mice by decreasing the activities of inflammasome components, oxidative stress and caspase-3
Yuanyuan Zhang et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2014)
P2X7 receptor: an emerging target in central nervous system diseases
Beata Sperlagh et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2014)
Ejaculatory Dysfunction
Elizabeth Phillips et al.
UROLOGIC CLINICS OF NORTH AMERICA (2014)
The two-hit hypothesis for neuroinflammation: role of exogenous ATP in modulating inflammation in the brain
Bernd L. Fiebich et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2014)
Role of adenosine in the antiepileptic effects of deep brain stimulation
Maisa F. Miranda et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2014)
Modulation of A(1) and A(2B) adenosine receptor activity: a new strategy to sensitise glioblastoma stem cells to chemotherapy
S. Daniele et al.
CELL DEATH & DISEASE (2014)
Pulmonary Infection with Hypervirulent Mycobacteria Reveals a Crucial Role for the P2X7 Receptor in Aggressive Forms of Tuberculosis
Eduardo P. Amaral et al.
PLOS PATHOGENS (2014)
Correlation between Urothelial Differentiation and Sensory Proteins P2X3, P2X5, TRPV1, and TRPV4 in Normal Urothelium and Papillary Carcinoma of Human Bladder
Igor Sterle et al.
BIOMED RESEARCH INTERNATIONAL (2014)
Evidence for Bladder Urothelial Pathophysiology in Functional Bladder Disorders
Susan K. Keay et al.
BIOMED RESEARCH INTERNATIONAL (2014)
Reversal of autism-like behaviors and metabolism in adult mice with single-dose antipurinergic therapy
J. C. Naviaux et al.
TRANSLATIONAL PSYCHIATRY (2014)
P2X4 receptors (P2X4Rs) represent a novel target for the development of drugs to prevent and/or treat alcohol use disorders
Kelle M. Franklin et al.
FRONTIERS IN NEUROSCIENCE (2014)
Impaired adenosine-mediated angiogenesis in preeclampsia: potential implications for fetal programming
Carlos Escudero et al.
FRONTIERS IN PHARMACOLOGY (2014)
Activation of adenosine receptor A2A increases HSC proliferation and inhibits death and senescence by down-regulation of p53 and Rb
Md. Kaimul Ahsan et al.
FRONTIERS IN PHARMACOLOGY (2014)
Effects of Brilliant Blue G on Serum Tumor Necrosis Factor- α Levels and Depression-like Behavior in Mice after Lipopolysaccharide Administration
Min Ma et al.
CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE (2014)
The role of p2x7 receptor in infectious inflammatory diseases and the influence of ectonucleotidases
Robson Coutinho-Silva et al.
Biomedical Journal (2014)
The impact of the P2X7 receptor antagonist A-804598 on neuroimmune and behavioral consequences of stress
Joseph M. Catanzaro et al.
BEHAVIOURAL PHARMACOLOGY (2014)
P2Y(2) receptor agonists for the treatment of dry eye disease: a review
Oliver C. F. Lau et al.
CLINICAL OPHTHALMOLOGY (2014)
The P2X7 Receptor Channel: Recent Developments and the Use of P2X7 Antagonists in Models of Disease
Rachael Bartlett et al.
PHARMACOLOGICAL REVIEWS (2014)
The Concept of Cotransmission: Focus on ATP as a Cotransmitter and its Significance in Health and Disease
Geoffrey Burnstock
EUROPEAN REVIEW (2014)
Role of P2X7 receptors in the development of diabetic retinopathy
Tetsuya Sugiyama
WORLD JOURNAL OF DIABETES (2014)
Purinergic Signaling and Blood Vessels in Health and Disease
Geoffrey Burnstock et al.
PHARMACOLOGICAL REVIEWS (2014)
The effects of adenosine A2A receptor knockout on renal interstitial fibrosis in a mouse model of unilateral ureteral obstruction
Hang Xiao et al.
ACTA HISTOCHEMICA (2013)
The adenosine A2A receptor agonist CGS 21680 decreases ethanol self-administration in both non-dependent and dependent animals
Hakim Houchi et al.
ADDICTION BIOLOGY (2013)
Epithelial Wounds Induce Differential Phosphorylation Changes in Response to Purinergic and EGF Receptor Activation
Amanuel Kehasse et al.
AMERICAN JOURNAL OF PATHOLOGY (2013)
Exhaled breath condensate adenosine tracks lung function changes in cystic fibrosis
Charles R. Esther et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2013)
A new rodent model for obstructive sleep apnea: effects on ATP-mediated dilations in cerebral arteries
Randy F. Crossland et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2013)
P2X7 Blockade Attenuates Murine Lupus Nephritis by Inhibiting Activation of the NLRP3/ASC/Caspase 1 Pathway
Jijun Zhao et al.
ARTHRITIS AND RHEUMATISM (2013)
Potential roles of adenosine deaminase-2 in diabetic retinopathy
Nehal M. Elsherbiny et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
Adenosine, adenosine receptors and glaucoma: An updated overview
Yisheng Zhong et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2013)
Expression and electrophysiological characteristics of P2X3 receptors in interstitial cells of Cajal in rats with partial bladder outlet obstruction
Yuxin Li et al.
BJU INTERNATIONAL (2013)
Antagonism of adenosine A2A receptor expressed by lung adenocarcinoma tumor cells and cancer associated fibroblasts inhibits their growth
Melanie Mediavilla-Varela et al.
CANCER BIOLOGY & THERAPY (2013)
Anthraquinone emodin inhibits human cancer cell invasiveness by antagonizing P2X7 receptors
Bilel Jelassi et al.
CARCINOGENESIS (2013)
Altered responsiveness to extracellular ATP enhances acetaminophen hepatotoxicity
Sylvia S. Amaral et al.
CELL COMMUNICATION AND SIGNALING (2013)
Adiponectin Receptor as a Key Player in Healthy Longevity and Obesity-Related Diseases
Toshimasa Yamauchi et al.
CELL METABOLISM (2013)
Targeting Adenosine Signaling to Treatment of Diabetic Nephropathy
Claudia Quezada et al.
CURRENT DRUG TARGETS (2013)
Effect of the Purinergic Inhibitor Oxidized ATP in a Model of Islet Allograft Rejection
Andrea Vergani et al.
DIABETES (2013)
Diminished Adenosine A1 Receptor Expression in Pancreatic α- Cells May Contribute to the Patholog y of Type 1 Diabetes
Linda Yip et al.
DIABETES (2013)
Targeting Purinergic Receptors in Islet Transplantation
Reid A. Aikin
DIABETES (2013)
The stimulation of A3 adenosine receptors reduces bone-residing breast cancer in a rat preclinical model
Katia Varani et al.
EUROPEAN JOURNAL OF CANCER (2013)
ATP and arterial calcification
Richard S. Fish et al.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2013)
Involvement of P2Y11 receptor in IFN-γ-induced IL-6 production in human keratinocytes
Makiko Ishimaru et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2013)
Adenosine signaling in airways: Toward a promising antiasthmatic approach
Carla Cicala et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2013)
Antidepressant- and anticompulsive-like effects of purinergic receptor blockade: Involvement of nitric oxide
Vitor S. Pereira et al.
EUROPEAN NEUROPSYCHOPHARMACOLOGY (2013)
Adenosine regulates bone metabolism via A1, A2A, and A2B receptors in bone marrow cells from normal humans and patients with multiple myeloma
Wenjie He et al.
FASEB JOURNAL (2013)
Extracellular UDP enhances P2X-mediated bladder smooth muscle contractility via P2Y6 activation of the phospholipase C/inositol trisphosphate pathway
Weiqun Yu et al.
FASEB JOURNAL (2013)
Promotion of Liver Regeneration by Natural Killer Cells in a Murine Model Is Dependent on Extracellular Adenosine Triphosphate Phosphohydrolysis
Nadine Graubardt et al.
HEPATOLOGY (2013)
Disordered purinergic signaling and abnormal cellular metabolism are associated with development of liver cancer in Cd39/Entpd1 null Mice
Xiaofeng Sun et al.
HEPATOLOGY (2013)
The P2Y13 receptor regulates extracellular ATP metabolism and the osteogenic response to mechanical loading
Ning Wang et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2013)
Influence of pressure on adenosine triphosphate function as a sympathetic neurotransmitter in small mesenteric arteries from the spontaneously hypertensive rat
Lakshman Goonetilleke et al.
JOURNAL OF HYPERTENSION (2013)
Signaling through Purinergic Receptors for ATP Induces Human Cutaneous Innate and Adaptive Th17 Responses: Implications in the Pathogenesis of Psoriasis
Meaghan E. Killeen et al.
JOURNAL OF IMMUNOLOGY (2013)
P2X7 receptor-mediated Nlrp3-inflammasome activation is a genetic determinant of macrophage-dependent crescentic glomerulonephritis
Simona Deplano et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2013)
P2X7 receptor-induced death of motor neurons by a peroxynitrite/FAS-dependent pathway
Mandi Gandelman et al.
JOURNAL OF NEUROCHEMISTRY (2013)
The purinergic 2X7 receptor participates in renal inflammation and injury induced by high-fat diet: possible role of NLRP3 inflammasome activation
Anna Solini et al.
JOURNAL OF PATHOLOGY (2013)
Decreased Intravesical Adenosine Triphosphate in Patients with Refractory Detrusor Overactivity and Bacteriuria
Colin A. Walsh et al.
JOURNAL OF UROLOGY (2013)
UROTHELIUM-RELEASED ATP CONTRIBUTES TO BLADDER DYSFUNCTION IN TYPE 2 DIABETES
Zongwei Wang et al.
JOURNAL OF UROLOGY (2013)
Assessment of peripheral blood CD4+adenosine triphosphate activity in patients with rheumatoid arthritis
Masaki Akimoto et al.
MODERN RHEUMATOLOGY (2013)
Adenosine increases nasal mucociliary clearance rate in mice through A2A and A2B adenosine receptors
Xiaoyang Hua et al.
LARYNGOSCOPE (2013)
ABT-702, an adenosine kinase inhibitor, attenuates inflammation in diabetic retinopathy
Nehal M. Elsherbiny et al.
LIFE SCIENCES (2013)
Physiological Roles and Potential Therapeutic Applications of the P2X7 Receptor in Inflammation and Pain
Luiz Anastacio Alves et al.
MOLECULES (2013)
Adenosine signaling in striatal circuits and alcohol use disorders
Hyung Wook Nam et al.
MOLECULES AND CELLS (2013)
Purinergic signalling during sterile liver injury
Andre G. Oliveira et al.
LIVER INTERNATIONAL (2013)
Astrocyte-derived ATP modulates depressive-like behaviors
Xiong Cao et al.
NATURE MEDICINE (2013)
Adenosine receptors as drug targets - what are the challenges?
Jiang-Fan Chen et al.
NATURE REVIEWS DRUG DISCOVERY (2013)
Adenosine and autism: A spectrum of opportunities
Susan A. Masino et al.
NEUROPHARMACOLOGY (2013)
OPIATE-INDUCED CHANGES IN BRAIN ADENOSINE LEVELS AND NARCOTIC DRUG RESPONSES
M. Wu et al.
NEUROSCIENCE (2013)
Correlation Between Cystometric Volumes, ATP Release, and pH in Women With Overactive Bladder Versus Controls
Ying Cheng et al.
NEUROUROLOGY AND URODYNAMICS (2013)
CF102 for the Treatment of Hepatocellular Carcinoma: A Phase I/II, Open-Label, Dose-Escalation Study
Salomon M. Stemmer et al.
ONCOLOGIST (2013)
Functional polymorphisms in the P2X7 receptor gene are associated with osteoporosis
L. B. Husted et al.
OSTEOPOROSIS INTERNATIONAL (2013)
Upregulation of P2X3 receptors by neuronal calcium sensor protein VILIP-1 in dorsal root ganglions contributes to the bone cancer pain in rats
Min Liu et al.
PAIN (2013)
A2A Adenosine Receptors Are Differentially Modulated by Pharmacological Treatments in Rheumatoid Arthritis Patients and Their Stimulation Ameliorates Adjuvant-Induced Arthritis in Rats
Fabrizio Vincenzi et al.
PLOS ONE (2013)
Urinary ATP May Be a Dynamic Biomarker of Detrusor Overactivity in Women with Overactive Bladder Syndrome
Miguel Silva-Ramos et al.
PLOS ONE (2013)
Adenosine 2A Receptor Antagonist Prevented and Reversed Liver Fibrosis in a Mouse Model of Ethanol-Exacerbated Liver Fibrosis
Dian J. Chiang et al.
PLOS ONE (2013)
The role of the adenosinergic system in lung fibrosis
Veronica Della Latta et al.
PHARMACOLOGICAL RESEARCH (2013)
Cardiovascular adenosine receptors: Expression, actions and interactions
John P. Headrick et al.
PHARMACOLOGY & THERAPEUTICS (2013)
The role of purinergic pathways in the pathophysiology of gut diseases: Pharmacological modulation and potential therapeutic applications
Luca Antonioli et al.
PHARMACOLOGY & THERAPEUTICS (2013)
Male contraception via simultaneous knockout of α1A-adrenoceptors and P2X1-purinoceptors in mice
Carl W. White et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Role of the ectonucleotidase NTPDase2 in taste bud function
Aurelie Vandenbeuch et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Mutation of the ATP-gated P2X2 receptor leads to progressive hearing loss and increased susceptibility to noise
Denise Yan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Non-synonymous polymorphisms in the P2RX 4 are related to bone mineral density and osteoporosis risk in a cohort of Dutch fracture patients
Anke Wesselius et al.
PURINERGIC SIGNALLING (2013)
The CD39-adenosinergic axis in the pathogenesis of renal ischemia-reperfusion injury
Veena Roberts et al.
PURINERGIC SIGNALLING (2013)
Purinergic signaling in inflammatory cells: P2 receptor expression, functional effects, and modulation of inflammatory responses
Fenila Jacob et al.
PURINERGIC SIGNALLING (2013)
Block of P2X7 receptors could partly reverse the delayed neuronal death in area CA1 of the hippocampus after transient global cerebral ischemia
Qiang Yu et al.
PURINERGIC SIGNALLING (2013)
Purinergic signalling in the musculoskeletal system
Geoffrey Burnstock et al.
PURINERGIC SIGNALLING (2013)
Purinergic signalling and cancer
Geoffrey Burnstock et al.
PURINERGIC SIGNALLING (2013)
Purinergic signalling and diabetes
Geoffrey Burnstock et al.
PURINERGIC SIGNALLING (2013)
Purinergic Receptor Antagonist A438079 Protects Against Acetaminophen-Induced Liver Injury by Inhibiting P450 Isoenzymes, Not by Inflammasome Activation
Yuchao Xie et al.
TOXICOLOGICAL SCIENCES (2013)
Endogenous A1 adenosine receptor protects mice from acute ethanol-induced hepatotoxicity
Ping Yang et al.
TOXICOLOGY (2013)
Alterations in the extracellular catabolism of nucleotides are involved in the antiproliferative effect of quercetin in human bladder cancer T24 cells
Liliana Rockenbach et al.
UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS (2013)
Desensitization properties of P2X3 receptors shaping pain signaling
Rashid Giniatullin et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2013)
A taste for ATP: neurotransmission in taste buds
Sue C. Kinnamon et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2013)
The therapeutic promise of ATP antagonism at P2X3 receptors in respiratory and urological disorders
Anthony P. Ford et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2013)
Adenosine and its receptors as therapeutic targets: An overview
Sakshi Sachdeva et al.
SAUDI PHARMACEUTICAL JOURNAL (2013)
P2X7 receptors in cerebral ischemia
Hui-Yu Bai et al.
NEUROSCIENCE BULLETIN (2013)
New Approaches to Thyroid Hormones and Purinergic Signaling
Gabriel Fernandes Silveira et al.
JOURNAL OF THYROID RESEARCH (2013)
Autoimmune Hepatitis: Clinical Review with Insights into the Purinergic Mechanism of Disease
Nikhil Kapila et al.
JOURNAL OF CLINICAL AND TRANSLATIONAL HEPATOLOGY (2013)
Concurrent Agonism of Adenosine A2B and Glucocorticoid Receptors in Human Airway Epithelial Cells Cooperatively Induces Genes with Anti-Inflammatory Potential: A Novel Approach to Treat Chronic Obstructive Pulmonary Disease
Stephanie Greer et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2013)
P2Y1 purinoceptor inhibition reduces extracellular signal-regulated protein kinase 1/2 phosphorylation in spinal cord and dorsal root ganglia: implications for cancer-induced bone pain
Jun Chen et al.
ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2012)
Pannexin1 contributes to pathophysiological ATP release in lipoapoptosis induced by saturated free fatty acids in liver cells
Feng Xiao et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2012)
Activated hepatic stellate cells upregulate transcription of ecto-5′-nucleotidase/CD73 via specific SP1 and SMAD promoter elements
Michel Fausther et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2012)
P2X7 receptor-mediated purinergic signaling promotes liver injury in acetaminophen hepatotoxicity in mice
Rafaz Hoque et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2012)
Clinical evaluation of the efficacy of the P2X7 purinergic receptor antagonist AZD9056 on the signs and symptoms of rheumatoid arthritis in patients with active disease despite treatment with methotrexate or sulphasalazine
Edward C. Keystone et al.
ANNALS OF THE RHEUMATIC DISEASES (2012)
CD73 protects kidney from ischemia-reperfusion injury through reduction of free radicals
Rongrong Jian et al.
APMIS (2012)
Adenosine Signaling Good or Bad in Erectile Function?
Jiaming Wen et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2012)
Regulation of Foam Cells by Adenosine
Allison B. Reiss et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2012)
Adenosine receptor antagonism suppresses functional and histological inflammatory changes in the rat urinary bladder
Patrik Aronsson et al.
AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL (2012)
ATP activates P2X receptors to mediate gap junctional coupling in the cochlea
Yan Zhu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)
Discovery of P2X3 selective antagonists for the treatment of chronic pain
Louis-David Cantin et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Modulation of bladder afferent signals in normal and spinal cord-injured rats by purinergic P2X3 and P2X2/3 receptors
Alvaro Munoz et al.
BJU INTERNATIONAL (2012)
Antitumor activity of zoledronic acid in primary breast cancer cells determined by the ATP tumor chemosensitivity assay
Tanja Fehm et al.
BMC CANCER (2012)
Mechanisms of constitutive and ATP-evoked ATP release in neonatal mouse olfactory epithelium
Sebastien Hayoz et al.
BMC NEUROSCIENCE (2012)
Adenosine triphosphate-based chemotherapy response assay-guided chemotherapy in unresectable colorectal liver metastasis
H. Hur et al.
BRITISH JOURNAL OF CANCER (2012)
The role of P2X7 purinergic receptors in inflammatory and nociceptive changes accompanying cyclophosphamide-induced haemorrhagic cystitis in mice
J. P. Martins et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
CD73-Deficient Mice Are Resistant to Carcinogenesis
John Stagg et al.
CANCER RESEARCH (2012)
Expression of P2X7 Receptor Increases In Vivo Tumor Growth
Elena Adinolfi et al.
CANCER RESEARCH (2012)
The His155Tyr (489C>T) single nucleotide polymorphism of P2RX7 gene confers an enhanced function of P2X7 receptor in immune cells from patients with rheumatoid arthritis
Liliana Portales-Cervantes et al.
CELLULAR IMMUNOLOGY (2012)
A novel fused 1,2,4-triazine aryl derivative as antioxidant and nonselective antagonist of adenosine A2A receptors in ethanol-activated liver stellate cells
Agnieszka Szuster-Ciesielska et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2012)
Adenosine A2a receptor stimulation prevents hepatocyte lipotoxicity and non-alcoholic steatohepatitis (NASH) in rats
Chiara Imarisio et al.
CLINICAL SCIENCE (2012)
Adenosine and protection from acute kidney injury
Steven C. Yap et al.
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION (2012)
Clinical Use of Clopidogrel
Nikolaus Sarafoff et al.
CURRENT PHARMACEUTICAL DESIGN (2012)
Functional up-regulation of P2X3 receptors in dorsal root ganglion in a rat model of bone cancer pain
J. X. Wu et al.
EUROPEAN JOURNAL OF PAIN (2012)
Chronic administration of the selective P2X3, P2X2/3 receptor antagonist, A-317491, transiently attenuates cancer-induced bone pain in mice
Rikke Rie Hansen et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2012)
Feasibility study of B16 melanoma therapy using oxidized ATP to target purinergic receptor P2X7
Fumie Hattori et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2012)
Botulinum Neurotoxin Serotype A Suppresses Neurotransmitter Release from Afferent as Well as Efferent Nerves in the Urinary Bladder
Youko Ikeda et al.
EUROPEAN UROLOGY (2012)
Purinergic P2Y2 Receptors Promote Neutrophil Infiltration and Hepatocyte Death in Mice With Acute Liver Injury
Cemil Korcan Ayata et al.
GASTROENTEROLOGY (2012)
Adenosine triphosphate-binding cassette transporter genes up-regulation in untreated hepatocellular carcinoma is mediated by cellular microRNAs
Florie Borel et al.
HEPATOLOGY (2012)
Platelet-derived adenosine 5′-triphosphate suppresses activation of human hepatic stellate cell: In vitro study
Naoya Ikeda et al.
HEPATOLOGY RESEARCH (2012)
P2X7 receptor antagonism attenuates the hypertension and renal injury in Dahl salt-sensitive rats
Xu Ji et al.
HYPERTENSION RESEARCH (2012)
Effects of nucleotides adenosine monophosphate and adenosine triphosphate in combination with L-arginine on male rabbit corpus cavernosum tissue
V. Hupertan et al.
INTERNATIONAL JOURNAL OF ANDROLOGY (2012)
Electromagnetic fields (EMFs) and adenosine receptors modulate prostaglandin E2 and cytokine release in human osteoarthritic synovial fibroblasts
A. Ongaro et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2012)
Dendritic cells tolerized with adenosine A2AR agonist attenuate acute kidney injury
Li Li et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Adenosine A2B Receptor Blockade Slows Growth of Bladder and Breast Tumors
Caglar Cekic et al.
JOURNAL OF IMMUNOLOGY (2012)
Adora2b Adenosine Receptor Signaling Protects during Acute Kidney Injury via Inhibition of Neutrophil-Dependent TNF-α Release
Almut Grenz et al.
JOURNAL OF IMMUNOLOGY (2012)
Clopidogrel and the risk of osteoporotic fractures: a nationwide cohort study
N. R. Jorgensen et al.
JOURNAL OF INTERNAL MEDICINE (2012)
Purinergic Signaling in Healthy and Diseased Skin
Geoffrey Burnstock et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2012)
Identification of a Promising Drug Candidate for the Treatment of Type 2 Diabetes Based on a P2Y1 Receptor Agonist
Shir Yelovitch et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
ATP acts as a survival signal and prevents the mineralization of aortic valve
Nancy Cote et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2012)
Spontaneous firing and evoked responses of spinal nociceptive neurons are attenuated by blockade of P2X3 and P2X2/3 receptors in inflamed rats
Jun Xu et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2012)
Suppression of Bladder Overactivity by Adenosine A2A Receptor Antagonist in a Rat Model of Parkinson Disease
Takeya Kitta et al.
JOURNAL OF UROLOGY (2012)
Purinergic P2X7 Receptors Participate in Disturbed Intracellular Calcium Homeostasis in Peripheral Blood Mononuclear Cells of Patients with Chronic Kidney Disease
Ingrid Lajdova et al.
KIDNEY & BLOOD PRESSURE RESEARCH (2012)
The modulation of hepatic adenosine triphosphate and inflammation by eicosapentaenoic acid during severe fibrotic progression in the SHRSP5/Dmcr rat model
Xiaofang Jia et al.
LIFE SCIENCES (2012)
Purinoceptor signaling in malaria-infected erythrocytes
Stephan M. Huber
MICROBES AND INFECTION (2012)
Activation of P2X7 Receptor by ATP Plays an Important Role in Regulating Inflammatory Responses during Acute Viral Infection
Benjamin H. Lee et al.
PLOS ONE (2012)
Activation of P2X7 Promotes Cerebral Edema and Neurological Injury after Traumatic Brain Injury in Mice
Donald E. Kimbler et al.
PLOS ONE (2012)
Protective Role of P2Y2 Receptor against Lung Infection Induced by Pneumonia Virus of Mice
Gilles Vanderstocken et al.
PLOS ONE (2012)
Adenosine induces cell-cycle arrest and apoptosis in androgen-dependent and -independent prostate cancer cell lines, LNcap-FGC-10, DU-145, and PC3
Mahmoud Aghaei et al.
PROSTATE (2012)
Effects of A2A adenosine receptor blockade or stimulation on alcohol intake in alcohol-preferring rats
Maria Vittoria Micioni Di Bonaventura et al.
PSYCHOPHARMACOLOGY (2012)
P2Y1 receptor activation by photolysis of caged ATP enhances neuronal network activity in the developing olfactory bulb
Timo Fischer et al.
PURINERGIC SIGNALLING (2012)
Anti-inflammatory effects of purine nucleosides, adenosine and inosine, in a mouse model of pleurisy: evidence for the role of adenosine A2 receptors
Fernanda da Rocha Lapa et al.
PURINERGIC SIGNALLING (2012)
Enhancement of Liver Regeneration by Adenosine Triphosphate-Sensitive K+ Channel Opener (Diazoxide) After Partial Hepatectomy
Yasuhiko Nakagawa et al.
TRANSPLANTATION (2012)
Adenosine receptor expression in rheumatoid synovium: a basis for methotrexate action
Lisa K. Stamp et al.
ARTHRITIS RESEARCH & THERAPY (2012)
Pathophysiology of Overactive Bladder
En Meng et al.
LUTS-LOWER URINARY TRACT SYMPTOMS (2012)
Purinergic Signaling in the Airways
Geoffrey Burnstock et al.
PHARMACOLOGICAL REVIEWS (2012)
A2A Adenosine Receptor (A2AAR) as a Therapeutic Target in Diabetic Retinopathy
Ahmed S. Ibrahim et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
Functional and morphological examinations of P1A1 purinoceptors in the normal and inflamed urinary bladder of the rat
Renata Vesela et al.
AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL (2011)
Activation of the P2Y1 receptor induces apoptosis and inhibits proliferation of prostate cancer cells
Qiang Wei et al.
BIOCHEMICAL PHARMACOLOGY (2011)
Receptor localization, native tissue binding and ex vivo occupancy for centrally penetrant P2X7 antagonists in the rat
S. L. Able et al.
BRITISH JOURNAL OF PHARMACOLOGY (2011)
P2Y1 Transient Overexpression Induced Mineralization in Spinal Ligament Cells Derived from Patients with Ossification of the Posterior Longitudinal Ligament of the Cervical Spine
Sunao Tanaka et al.
CALCIFIED TISSUE INTERNATIONAL (2011)
Adenosine deaminase in saliva as a diagnostic marker of squamous cell carcinoma of tongue
Balwant Rai et al.
CLINICAL ORAL INVESTIGATIONS (2011)
Parallel Regulation of extracellular ATP and inorganic pyrophosphate: Roles of growth factors, transduction modulators, and ANK
Jill C. Costello et al.
CONNECTIVE TISSUE RESEARCH (2011)
Altered purinergic signaling in CD73-deficient mice inhibits tumor progression
Gennady G. Yegutkin et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2011)
ATP RELEASE FROM BLADDERS IS INCREASED IN-VIVO AND SUPPRESSED BY ALPHA-1 ADRENOCEPTOR BLOCKER IN A RAT MODEL OF BLADDER OUTLET OBSTRUCTION
H. Akino et al.
EUROPEAN UROLOGY SUPPLEMENTS (2011)
A potential therapeutic role for P2X7 receptor (P2X7R) antagonists in the treatment of inflammatory diseases
Nishkantha Arulkumaran et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2011)
P2X7 receptor signaling contributes to tissue factor-dependent thrombosis in mice
Christian Furlan-Freguia et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Tetanic failure due to decreased endogenous adenosine A2A tonus operating neuronal Cav1 (L-type) influx in Myasthenia gravis
J. B. Noronha-Matos et al.
JOURNAL OF NEUROCHEMISTRY (2011)
Novel molecular targets for prevention of obesity and osteoporosis
Srujana Rayalam et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2011)
UV-B induced alteration in purinergic receptors and signaling on HaCaT keratinocytes
Olga Ruzsnavszky et al.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2011)
CGS 21680, an Agonist of the Adenosine (A2A) Receptor, Reduces Progression of Murine Type II Collagen-induced Arthritis
Emanuela Mazzon et al.
JOURNAL OF RHEUMATOLOGY (2011)
Inhibition of the P2X7 Receptor Reduces Cystogenesis in PKD
Ming-Yang Chang et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2011)
Correlation of changes in pain intensity with synovial fluid adenosine triphosphate levels after treatment of patients with osteoarthritis of the knee with high-molecular-weight hyaluronic acid
Nobuyuki Kumahashi et al.
KNEE (2011)
P2Y2 receptor-mediated modulation of estrogen-induced proliferation of breast cancer cells
Han-jun Li et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2011)
Adenosine abolishes MTX-induced suppression of osteoclastogenesis and inflammatory bone destruction in adjuvant-induced arthritis
Junpei Teramachi et al.
LABORATORY INVESTIGATION (2011)
Common variants in P2RY11 are associated with narcolepsy
Birgitte R. Kornum et al.
NATURE GENETICS (2011)
P2X7 receptor-deficient mice are susceptible to bone cancer pain
Rikke Rie Hansen et al.
PAIN (2011)
Involvement of P2Y6 Receptor in p38 MAPK-Mediated COX-2 Expression in Response to UVB Irradiation of Human Keratinocytes
Erina Takai et al.
RADIATION RESEARCH (2011)
Purinergic signalling: From normal behaviour to pathological brain function
Geoffrey Burnstock et al.
PROGRESS IN NEUROBIOLOGY (2011)
Adenosine 2A receptor: a crucial neuromodulator with bidirectional effect in neuroinflammation and brain injury
Shuang-Shuang Dai et al.
REVIEWS IN THE NEUROSCIENCES (2011)
Liver damage and systemic inflammatory responses are exacerbated by the genetic deletion of CD39 in total hepatic ischemia
Xiaofeng Sun et al.
PURINERGIC SIGNALLING (2011)
Nucleotide receptors as targets in the pharmacological enhancement of dermal wound healing
Edyta Gendaszewska-Darmach et al.
PURINERGIC SIGNALLING (2011)
European meeting P2 receptors: new targets for the treatment of osteoporosis
Niklas Rye Jorgensen et al.
PURINERGIC SIGNALLING (2011)
Effects of diadenosine tetraphosphate on FGF9-induced chloride flux changes in achondroplastic chondrocytes
Fernando Huete et al.
PURINERGIC SIGNALLING (2011)
ATP Mediates Neuroprotective and Neuroproliferative Effects in Mouse Olfactory Epithelium following Exposure to Satratoxin G In Vitro and In Vivo
Cuihong Jia et al.
TOXICOLOGICAL SCIENCES (2011)
Vascular CD39/ENTPD1 Directly Promotes Tumor Cell Growth by Scavenging Extracellular Adenosine Triphosphate
Lili Feng et al.
NEOPLASIA (2011)
NK1.1+ Cells and CD8+ T Cells Mediate the Antitumor Activity of Cl-IB-MECA in a Mouse Melanoma Model
Silvana Morello et al.
NEOPLASIA (2011)
Immune cell regulation by autocrine purinergic signalling
Wolfgang G. Junger
NATURE REVIEWS IMMUNOLOGY (2011)
ATP as a death factor: purinergic signaling in renal epithelial-fibroblast cross talk
Abolfazl Zarjou et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2011)
Purinergic P2X Receptor Regulates N-Methyl-D-aspartate Receptor Expression and Synaptic Excitatory Amino Acid Concentration in Morphine-tolerant Rats
Yueh-Hua Tai et al.
ANESTHESIOLOGY (2010)
The role of adenosine receptors in rheumatoid arthritis
Katia Varani et al.
AUTOIMMUNITY REVIEWS (2010)
gamma-Irradiation induces P2X(7) receptor-dependent ATP release from B16 melanoma cells
Yasuhiro Ohshima et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2010)
Structure-activity relationships and in vivo activity of (1H-pyrazol-4-yl)acetamide antagonists of the P2X7 receptor
Paul J. Beswick et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
Systemic blockade of P2X3 and P2X2/3 receptors attenuates bone cancer pain behaviour in rats
Timothy K. Y. Kaan et al.
BRAIN (2010)
Expression and functional role of adenosine receptors in regulating inflammatory responses in human synoviocytes
K. Varani et al.
BRITISH JOURNAL OF PHARMACOLOGY (2010)
Effect of tetramethylpyrazine on DRG neuron P2X3 receptor involved in transmitting pain after burn
Yun Gao et al.
BURNS (2010)
Effect of Extracellular ATP on Cisplatin-Induced Cytotoxicity in Human Ovarian Carcinoma Cells
Anand Rotte et al.
CHEMOTHERAPY (2010)
In Vitro Release of Adenosine Triphosphate from the Urothelium of Human Bladders with Detrusor Overactivity, Both Neurogenic and Idiopathic
Vivek Kumar et al.
EUROPEAN UROLOGY (2010)
P2X7 Receptors Mediate Ischemic Damage to Oligodendrocytes
Maria Domercq et al.
GLIA (2010)
Functional variants of the P2RX7 gene, aseptic osteolysis, and revision of the total hip arthroplasty:A preliminary study
F. Mrazek et al.
HUMAN IMMUNOLOGY (2010)
Expression and function of the P2X7 purinergic receptor in patients with systemic lupus erythematosus and rheumatoid arthritis
Liliana Portales-Cervantes et al.
HUMAN IMMUNOLOGY (2010)
Hypoxia-inducible adenosine A2B receptor modulates proliferation of colon carcinoma cells
De-Fu Ma et al.
HUMAN PATHOLOGY (2010)
Blocking P2X receptors can inhibit the injury-induced proliferation of olfactory epithelium progenitor cells in adult mouse
Liang Gao et al.
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY (2010)
The P2Y2 Receptor Sensitizes Mouse Bladder Sensory Neurons and Facilitates Purinergic Currents
Xiaowei Chen et al.
JOURNAL OF NEUROSCIENCE (2010)
Comparison of the peripheral mediator background of heat injury- and plantar incision-induced drop of the noxious heat threshold in the rat
Reka Fueredi et al.
LIFE SCIENCES (2010)
Polycystins and renovascular mechanosensory transduction
Amanda Patel et al.
NATURE REVIEWS NEPHROLOGY (2010)
Purinergic Receptor Functionality Is Necessary for Infection of Human Hepatocytes by Hepatitis Delta Virus and Hepatitis B Virus
John M. Taylor et al.
PLOS ONE (2010)
A multi-scale view of skin thermal pain: from nociception to pain sensation
Y. J. Zhu et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES (2010)
Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis
John Stagg et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
The effects of P2X7 receptor antagonists on the formation and function of human osteoclasts in vitro
Ankita Agrawal et al.
PURINERGIC SIGNALLING (2010)
Platelet hyper-reactivity in active inflammatory arthritis is unique to the adenosine diphosphate pathway: a novel finding and potential therapeutic target
Paul A. Mac Mullan et al.
RHEUMATOLOGY (2010)
Adenosine 5′-triphosphate infusions reduced disease activity and inflammation in a patient with active rheumatoid arthritis
Martijn J. L. Bours et al.
RHEUMATOLOGY (2010)
Butyl benzyl phthalate suppresses the ATP-induced cell proliferation in human osteosarcoma HOS cells
Pei-Shan Liu et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2010)
ADP-dependent platelet function prior to and in the early course of pediatric Liver transplantation and persisting thrombocytopenia are positively correlated with ischemia/reperfusion injury
Jan Schulte Am Esch et al.
TRANSPLANT INTERNATIONAL (2010)
Activation of Adenosine A2A Receptor Attenuates Inflammatory Response in a Rat Model of Small-for-Size Liver Transplantation
L. -M. Tang et al.
TRANSPLANTATION PROCEEDINGS (2010)
Protective Effect of Tonapofylline (BG9928), an Adenosine A(1) Receptor Antagonist, against Cisplatin-Induced Acute Kidney Injury in Rats
Alan Gill et al.
AMERICAN JOURNAL OF NEPHROLOGY (2009)
Synthesis of ATP derivatives of compounds of the mevalonate pathway (isopentenyl di- and triphosphate; geranyl di- and triphosphate, farnesyl di- and triphosphate, and dimethylallyl diphosphate) catalyzed by T4 RNA ligase, T4 DNA ligase and other ligases Potential relationship with the effect of bisphosphonates on osteoclasts
Maria A. Guenther Sillero et al.
BIOCHEMICAL PHARMACOLOGY (2009)
Deficiency of polycystic kidney disease-1 gene (PKD1) expression increases A3 adenosine receptors in human renal cells: Implications for cAMP-dependent signalling and proliferation of PKD1-mutated cystic cells
Gianluca Aguiari et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2009)
Effects of ageing and streptozotocin-induced diabetes on connexin43 and P2 purinoceptor expression in the rat corpora cavernosa and urinary bladder
Sylvia O. Suadicani et al.
BJU INTERNATIONAL (2009)
ADA-deficient SCID is associated with a specific microenvironment and bone phenotype characterized by RANKL/OPG imbalance and osteoblast insufficiency
Aisha V. Sauer et al.
BLOOD (2009)
Activation of P2X7-mediated apoptosis Inhibits DMBA/TPA-induced formation of skin papillomas and cancer in mice
Wen Fu et al.
BMC CANCER (2009)
Differential responses of cells from human skin keratinocyte and bovine mammary epithelium to attack by pore-forming Staphylococcus aureus α-toxin
Gunnaporn Suriyaphol et al.
COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES (2009)
P2X7-mediated chemoprevention of epithelial cancers
George I. Gorodeski
EXPERT OPINION ON THERAPEUTIC TARGETS (2009)
Purinergic receptor-mediated effects of adenosine 5'-triphosphate in urological malignant diseases
Majid Shabbir et al.
INTERNATIONAL JOURNAL OF UROLOGY (2009)
In Vivo Infusion of UTP and Uridine to the Deafened Guinea Pig Inner Ear: Effects on Response Thresholds and Neural Survival
Anette Fransson et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2009)
Adenosine Administration Accelerates Progression of the Cell Cycle during Rat Liver Regeneration Induced by One-Third Hepatectomy
Edgar Mendieta-Condado et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2009)
Adenosine Signaling, Priapism and Novel Therapies
Yingbo Dai et al.
JOURNAL OF SEXUAL MEDICINE (2009)
P2X(7) Deficiency Attenuates Renal Injury in Experimental Glomerulonephritis
Simon R. J. Taylor et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2009)
Management of Erectile Function by Penile Purinergic P2 Receptors in the Diabetic Rat
Serap Gur et al.
JOURNAL OF UROLOGY (2009)
Purinergic mechanosensory transduction and visceral pain
Geoffrey Burnstock
MOLECULAR PAIN (2009)
Role of Extracellular Adenosine in Acute Lung Injury
Tobias Eckle et al.
PHYSIOLOGY (2009)
Human Placental Adenosine Receptor Expression is Elevated in Preeclampsia and Hypoxia Increases Expression of the A2A Receptor
F. von Versen-Hoeynck et al.
PLACENTA (2009)
Adenosine analogs and electromagnetic fields inhibit prostaglandin E2 release in bovine synovial fibroblasts
M. De Mattei et al.
OSTEOARTHRITIS AND CARTILAGE (2009)
Systemic administration of an antagonist of the ATP-sensitive receptor P2X7 improves recovery after spinal cord injury
Weiguo Peng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
An imbalance between apoptosis and proliferation contributes to follicular persistence in polycystic ovaries in rats
Natalia R. Salvetti et al.
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY (2009)
An in vivo model of melanoma: treatment with ATP
Nicholas White et al.
PURINERGIC SIGNALLING (2009)
P2X7 receptor expression is decreased in epithelial cancer cells of ectodermal, uro-genital sinus, and distal paramesonephric duct origin
Xin Li et al.
PURINERGIC SIGNALLING (2009)
Genetics of the P2X7 receptor and human disease
Stephen J. Fuller et al.
PURINERGIC SIGNALLING (2009)
Uridine-5′-triphosphate Protects Against Hepatic-Ischemic/Reperfusion Injury in Mice
Ziv Ben-Ari et al.
TRANSPLANTATION (2009)
Purinergic signaling in special senses
Gary D. Housley et al.
TRENDS IN NEUROSCIENCES (2009)
A2B and A3 Adenosine Receptors Modulate Vascular Endothelial Growth Factor and Interleukin-8 Expression in Human Melanoma Cells Treated with Etoposide and Doxorubicin
Stefania Merighi et al.
NEOPLASIA (2009)
Adenosine A3 Receptor Suppresses Prostate Cancer Metastasis by Inhibiting NADPH Oxidase Activity
Sarvesh Jajoo et al.
NEOPLASIA (2009)
MDA-MB-231 produces ATP-mediated ICAM-1-dependent facilitation of the attachment of carcinoma cells to human lymphatic endothelial cells
Yoshiko Kawai et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2008)
Neuronally Released Sympathetic Neurotransmitters Stimulate Splenic Interferon-γ Secretion From T Cells in Early Type II Collagen-Induced Arthritis
Rainer H. Straub et al.
ARTHRITIS AND RHEUMATISM (2008)
Radioprotective effects of ATP in human blood ex vivo
Els L. R. Swennen et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Change in acetylcholine release from rat bladder with partial outlet obstruction
Shigetaka Murakami et al.
BJU INTERNATIONAL (2008)
A functional study of purinergic signalling in the normal and pathological rabbit corpus cavernosum
Robert C. Calvert et al.
BJU INTERNATIONAL (2008)
P2Y receptors activated by diadenosine polyphosphates reestablish Ca2+ transients in achondroplasic chondrocytes
Ana Guzman-Aranguez et al.
BONE (2008)
Cell Death Induced by Uridine 5'-triphosphate (UTP) in Contrast to Adenosine 5'-triphosphate (ATP) in Human Epidermoid Carcinoma Cells (A-431)
Thomas M. K. Voelkl et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2008)
ATP, calcium and magnesium levels in platelets of patients with primary fibromyalgia
Laura Bazzichi et al.
CLINICAL BIOCHEMISTRY (2008)
The P2X7 receptor as a therapeutic target
Romeo Romagnoli et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2008)
APT102, a novel ADPase, cooperates with aspirin to disrupt bone metastasis in mice
Oezge Uluckan et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2008)
Targeting therapy for breast carcinoma by ATP synthase inhibitor aurovertin B
Tsui-Chin Huang et al.
JOURNAL OF PROTEOME RESEARCH (2008)
Critical role of hypoxia and A2A adenosine receptors in liver tissue-protecting physiological anti-inflammatory pathway
Alexander Chouker et al.
MOLECULAR MEDICINE (2008)
Purinergic signalling and disorders of the central nervous system
Geoffrey Burnstock
NATURE REVIEWS DRUG DISCOVERY (2008)
Reg-2 expression in dorsal root ganglion neurons after adjuvant-induced monoarthritis
S. Averill et al.
NEUROSCIENCE (2008)
Human equilibrative nucleoside transporters 1 and 2 may be differentially modulated by A2B adenosine receptors in placenta microvascular endothelial cells from pre-eclampsia
C. Escudero et al.
PLACENTA (2008)
Contrasting effects of P2 receptor agonists on spontaneous contractility of human fallopian tubes with and without acute inflammation
Airat U. Ziganshin et al.
PHARMACOLOGICAL RESEARCH (2008)
ATP release from the human ureter on distension and P2X3 receptor expression on suburothelial sensory nerves
R. C. Calvert et al.
PURINERGIC SIGNALLING (2008)
Drug Insight: biological effects of botulinum toxin A in the lower urinary tract
Michael B. Chancellor et al.
NATURE CLINICAL PRACTICE UROLOGY (2008)
Cerebral A1 adenosine receptors (A1AR) in liver cirrhosis
Christian Boy et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2008)
Bench-to-bedside review: Adenosine receptors - promising targets in acute lung injury?
Carsten P. Schepp et al.
CRITICAL CARE (2008)
P2 receptors in cardiovascular regulation and disease
David Erlinge et al.
PURINERGIC SIGNALLING (2008)
The anti-inflammatory effect of A3 adenosine receptor agonists:: a novel targeted therapy for rheumatoid arthritis
Sara Bar-Yehuda et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2007)
Effect of the purinergic receptor P2X7 on Chlamydia infection in cervical epithelial cells and vaginally infected mice
Toni Darville et al.
JOURNAL OF IMMUNOLOGY (2007)
Decreased expression of P2X7 in endometrial epithelial pre-cancerous and cancer cells
Xin Li et al.
GYNECOLOGIC ONCOLOGY (2007)
Purine and pyrimidine receptors
G. Burnstock
CELLULAR AND MOLECULAR LIFE SCIENCES (2007)
Post-translational modifications of the P2X4 purinergic receptor subtype in the human placenta are altered in preeclampsia
V. H. J. Roberts et al.
PLACENTA (2007)
Molecular basis for calcium signaling in hepatic stellate cells
Emma A. Kruglov et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2007)
A polymorphism in the P2X7 gene increases susceptibility to extrapulmonary tuberculosis
Suran L. Fernando et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2007)
Physiology and pharmacology of the human ureter: Basis for current and future treatments
A. Erdem Canda et al.
UROLOGIA INTERNATIONALIS (2007)
Purinergic (P2) receptor control of lower genitourinary tract function and new avenues for drug action: An overview
Serap Gur et al.
CURRENT PHARMACEUTICAL DESIGN (2007)
Pro-fibrotic roles of the A2B adenosine receptor in human primary hepatic stellate cells
H. Zhong et al.
JOURNAL OF HEPATOLOGY (2007)
The use of the isolated mouse whole bladder for investigating bladder overactivity
Adebola C. Fabiyi et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
The application of botulinum toxin in the prostate
Yao-Chi Chuang et al.
JOURNAL OF UROLOGY (2006)
Phospholipase D and extracellular signal-regulated kinase in hepatic stellate cells: effects of platelet-derived growth factor and extracellular nucleotides
Joaquin Benitez-Rajal et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2006)
Relationship between genetic variants in the adenosine pathway and outcome of methotrexate treatment in patients with recent-onset rheumatoid arthritis
Judith A. M. Wessels et al.
ARTHRITIS AND RHEUMATISM (2006)
Adenosine A2b receptor is highly expressed in human hepatocellular carcinoma
Hong-jun Xiang et al.
HEPATOLOGY RESEARCH (2006)
Adenosine A2A receptors play a role in the pathogenesis of hepatic cirrhosis
Edwin S. L. Chan et al.
BRITISH JOURNAL OF PHARMACOLOGY (2006)
Time dependent changes in diabetic cystopathy in rats include compensated and decompensated bladder function
Firouz Daneshgari et al.
JOURNAL OF UROLOGY (2006)
A truncated P2X7 receptor variant (P2X7-j) endogenously expressed in cervical cancer cells antagonizes the full-length P2X7 receptor through hetero-oligomerization
Ying-Hong Feng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Pathophysiology and therapeutic potential of purinergic signaling
G Burnstock
PHARMACOLOGICAL REVIEWS (2006)
Pharmacological characterization of urinary bladder smooth muscle contractility following partial bladder outlet obstruction in pigs
I Milicic et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2006)
P2X7 receptors regulate NKT cells in autoimmune hepatitis
H Kawamura et al.
JOURNAL OF IMMUNOLOGY (2006)
Decreased sensory receptors P2X3 and TRPV1 in suburothelial nerve fibers following intradetrusor injections of botulinum toxin for human detrusor overactivity
A Apostolidis et al.
JOURNAL OF UROLOGY (2005)
Human melanomas express functional P2X7 receptors
N White et al.
CELL AND TISSUE RESEARCH (2005)
Enhanced ATP release from rat bladder urothelium during chronic bladder inflammation: Effect of botulinum toxin A
CP Smith et al.
NEUROCHEMISTRY INTERNATIONAL (2005)
Characteristics of sensory DRG neurons innervating the lumbar facet joints in rats
T Ishikawa et al.
EUROPEAN SPINE JOURNAL (2005)
Effect of botulinum toxin on detrusor overactivity induced by intravesical adenosine triphosphate and capsaicin in a rat model
H Atiemo et al.
UROLOGY (2005)
Plasma adenosine concentrations increase in women with hyperemesis gravidarum
Y Yoneyama et al.
CLINICA CHIMICA ACTA (2004)
Early prostate cancer detected using expression of non-functional cytolytic P2X7 receptors
M Slater et al.
HISTOPATHOLOGY (2004)
Reducing joint destruction due to septic arthrosis using an adenosine2A receptor agonist
SB Cohen et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2004)
Extracellular ATP activates c-jun N-terminal kinase signaling and cell cycle progression in hepatocytes
S Thevananther et al.
HEPATOLOGY (2004)
Innervation of immune cells: Evidence for neuroimmunomodulation in the liver
WL Neuhuber et al.
ANATOMICAL RECORD PART A-DISCOVERIES IN MOLECULAR CELLULAR AND EVOLUTIONARY BIOLOGY (2004)
P2X7 receptor inhibition improves recovery after spinal cord injury
XH Wang et al.
NATURE MEDICINE (2004)
Activation of ureter nociceptors by exogenous and endogenous ATP in guinea pig
WF Rong et al.
NEUROPHARMACOLOGY (2004)
Glomerular expression of the ATP-sensitive P2X7 receptor in diabetic and hypertensive rat models
O Vonend et al.
KIDNEY INTERNATIONAL (2004)
Adenosine stimulation of proliferation of breast carcinoma cell lines:: Evaluation of the [3H]thymidine assay system and modulatory effects of the cellular microenvironment in vitro
M Mujoomdar et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2004)
Purinoceptor expression in regenerating skeletal muscle in the mdx mouse model of muscular dystrophy and in satellite cell cultures
M Ryten et al.
FASEB JOURNAL (2004)
Changes in intracellular calcium concentration and P2X(1) receptor expression in hypertrophic rat urinary bladder smooth muscle
RS Scott et al.
NEUROUROLOGY AND URODYNAMICS (2004)
Ovariectomy and estradiol replacement therapy alters the adenine nucleotide hydrolysis in rat blood serum
D Pochmann et al.
THROMBOSIS RESEARCH (2004)
Therapeutic implications of central and peripheral neurologic mechanisms in migraine
C Waeber et al.
NEUROLOGY (2003)
Randomized clinical trial of adenosine 5′-triphosphate on tumor growth and survival in advanced lung cancer patients
HJ Agteresch et al.
ANTI-CANCER DRUGS (2003)
Specific increase in enzymatic activity of adenosine deaminase 1 in rheumatoid synovial fibroblasts
Y Nakamachi et al.
ARTHRITIS AND RHEUMATISM (2003)
Adenosine triphosphate activates mitogen-activated protein kinase in pre-neoplastic and neoplastic ovarian surface epithelial cells
KC Choi et al.
BIOLOGY OF REPRODUCTION (2003)
Pharmacologic perspective on the physiology of the lower urinary tract
KE Andersson et al.
UROLOGY (2002)
Chronic ethanol consumption impairs adrenoceptor- and purinoceptor-mediated relaxations in isolated rat detrusor smooth muscle
RC Calvert et al.
BJU INTERNATIONAL (2002)
Future drugs for the treatment of benign prostatic hyperplasia
KE Andersson et al.
WORLD JOURNAL OF UROLOGY (2002)
ATP is released from guinea pig ureter epithelium on distension
GE Knight et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2002)
Purinergic signaling and vascular cell proliferation and death
G Burnstock
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2002)
P2X receptors and their role in female idiopathic detrusor instability
BA O'Reilly et al.
JOURNAL OF UROLOGY (2002)
Neurotransmission and drug effects in urethral smooth muscle
KE Andersson
SCANDINAVIAN JOURNAL OF UROLOGY AND NEPHROLOGY (2001)
Sympathetic overactivity and arterial hypertension in renal failure
SR Orth et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2001)
Expression of nucleotide P2X receptor subtypes during spermatogenesis in the adult rat testis
R Glass et al.
CELLS TISSUES ORGANS (2001)
Urinary bladder hyporeflexia and reduced pain-related behaviour in P2X3-deficient mice
DA Cockayne et al.
NATURE (2000)
Reduced vas deferens contraction and male infertility in mice lacking P2X1 receptors
K Mulryan et al.
NATURE (2000)
Therapeutic potential of adenosine kinase inhibitors
EA Kowaluk et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2000)
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