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GI Lancaster et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Co-chaperone CHIP associates with expanded polyglutamine protein and promotes their degradation by proteasomes
NR Jana et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Navigating the chaperone network: An integrative map of physical and genetic interactions mediated by the Hsp90 chaperone
RM Zhao et al.
CELL (2005)
Caloric restriction attenuates beta-amyloid neuropathology in a mouse model of Alzheimer's disease
J Wang et al.
FASEB JOURNAL (2005)
Modulation of neurodegeneration by molecular chaperones
PJ Muchowski et al.
NATURE REVIEWS NEUROSCIENCE (2005)
HsD70 gene transfer by adeno-associated virus inhibits MPTP-induced nigrostriatal degeneration in the mouse model of Parkinson disease
ZZ Dong et al.
MOLECULAR THERAPY (2005)
Propagation of Saccharomyces cerevisiae [PSI+] prion is impaired by factors that regulate Hsp70 substrate binding
G Jones et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Binding of tau to heat shock protein 27 leads to decreased concentration of hyperphosphorylated tau and enhanced cell survival
H Shimura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation
L Petrucelli et al.
HUMAN MOLECULAR GENETICS (2004)
Proteasomal inhibition by α-synuclein filaments and oligomers
E Lindersson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Nuclear translocation of the Hsp70/Hsp90 organizing protein mSTI1 is regulated by cell cycle kinases
VM Longshaw et al.
JOURNAL OF CELL SCIENCE (2004)
Geldanamycin induces Hsp70 and prevents α-synuclein aggregation and toxicity in vitro
PJ McLean et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Hsp70 and Hsp40 attenuate formation of spherical and annular polyglutamine oligomers by partitioning monomer
JL Wacker et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2004)
The controversial protein-only hypothesis of prion propagation
C Soto et al.
NATURE MEDICINE (2004)
Expression of the small heat-shock protein alpha B-crystallin in tauopathies with glial pathology
DV Dabir et al.
AMERICAN JOURNAL OF PATHOLOGY (2004)
Hsp70 reduces α-synuclein aggregation and toxicity
J Klucken et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Autophagosome-like vacuole formation in Huntington's disease lymphoblasts
E Nagata et al.
NEUROREPORT (2004)
Tetratricopeptide repeat cochaperones in steroid receptor complexes
DF Smith
CELL STRESS & CHAPERONES (2004)
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
M Arrasate et al.
NATURE (2004)
CHIP activates HSF1 and confers protection against apoptosis and cellular stress
Q Dai et al.
EMBO JOURNAL (2003)
Aha1 binds to the middle domain of Hsp90, contributes to client protein activation, and stimulates the ATPase activity of the molecular chaperone
GP Lotz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
H2O2 and 4-hydroxynonenal mediate amyloid β-induced neuronal apoptosis by activating JNKs and p38MAPK
E Tamagno et al.
EXPERIMENTAL NEUROLOGY (2003)
Structural and functional analysis of the middle segment of Hsp90: Implications for ATP hydrolysis and client protein and cochaperone interactions
P Meyer et al.
MOLECULAR CELL (2003)
Chaperones increase association of tau protein with microtubules
F Dou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Neuropathology of prion diseases
H Budka
BRITISH MEDICAL BULLETIN (2003)
TorsinA and heat shock proteins act as molecular chaperones:: suppression of α-synuclein aggregation
PJ McLean et al.
JOURNAL OF NEUROCHEMISTRY (2002)
Stress-inducible protein 1 is a cell surface ligand for cellular prion that triggers neuroprotection
SM Zanata et al.
EMBO JOURNAL (2002)
Cellular prion protein transduces neuroprotective signals
LB Chiarini et al.
EMBO JOURNAL (2002)
Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo
DM Walsh et al.
NATURE (2002)
Chaperone suppression of α-synuclein toxicity in a Drosophila model for Parkinson's disease
PK Auluck et al.
SCIENCE (2002)
Prominent stress response of Purkinje cells in Creutzfeldt-Jakob disease
GG Kovács et al.
NEUROBIOLOGY OF DISEASE (2001)
Targeting small Aβ oligomers:: the solution to an Alzheimer's disease conundrum?
WL Klein et al.
TRENDS IN NEUROSCIENCES (2001)
The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation
GC Meacham et al.
NATURE CELL BIOLOGY (2001)
The in vitro phosphorylation of the co-chaperone mSTI1 by cell cycle kinases substantiates a predicted casein kinase II-p34cdc2-NLS (CcN) motif
VM Longshaw et al.
BIOLOGICAL CHEMISTRY (2000)
Bacterial and yeast chaperones reduce both aggregate formation and cell death in mammalian cell models of Huntington's disease
J Carmichael et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Polyglutamine length-dependent interaction of Hsp40 and Hsp70 family chaperones with truncated N-terminal huntingtin: their role in suppression of aggregation and cellular toxicity
NR Jana et al.
HUMAN MOLECULAR GENETICS (2000)
Structure of TPR domain-peptide complexes: Critical elements in the assembly of the Hsp70-Hsp90 multichaperone machine
C Scheufler et al.
CELL (2000)
Genetic suppression of polyglutamine toxicity in Drosophila
P Kazemi-Esfarjani et al.
SCIENCE (2000)
The U box is a modified RING finger - a common domain in ubiquitination
L Aravind et al.
CURRENT BIOLOGY (2000)
Aggregation of huntingtin in yeast varies with the length of the polyglutamine expansion and the expression of chaperone proteins
S Krobitsch et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
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