相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Viral gene transfer of APPsα rescues synaptic failure in an Alzheimer's disease mouse model
Romain Fol et al.
ACTA NEUROPATHOLOGICA (2016)
Modular composition and dynamics of native GABAB receptors identified by high-resolution proteomics
Jochen Schwenk et al.
NATURE NEUROSCIENCE (2016)
Amyloid precursor protein maintains constitutive and adaptive plasticity of dendritic spines in adult brain by regulating D-serine homeostasis
Chengyu Zou et al.
EMBO JOURNAL (2016)
Amyloid precursor-like protein 1 (APLP1) exhibits stronger zinc-dependent neuronal adhesion than amyloid precursor protein and APLP2
Magnus C. Mayer et al.
JOURNAL OF NEUROCHEMISTRY (2016)
Amyloid Precursor Protein Protects Neuronal Network Function after Hypoxia via Control of Voltage-Gated Calcium Channels
Dimitri Hefter et al.
JOURNAL OF NEUROSCIENCE (2016)
CELLULAR AND SYSTEM BIOLOGY OF MEMORY: TIMING, MOLECULES, AND BEYOND
Martin Korte et al.
PHYSIOLOGICAL REVIEWS (2016)
Impaired theta-gamma coupling in APP-deficient mice
Xiaomin Zhang et al.
SCIENTIFIC REPORTS (2016)
APP Is a Context-Sensitive Regulator of the Hippocampal Presynaptic Active Zone
Melanie Lassek et al.
PLOS COMPUTATIONAL BIOLOGY (2016)
FE65 and FE65L1 share common synaptic functions and genetically interact with the APP family in neuromuscular junction formation
Paul Strecker et al.
SCIENTIFIC REPORTS (2016)
Cellular Functions of the Amyloid Precursor Protein from Development to Dementia
Rik van der Kant et al.
DEVELOPMENTAL CELL (2015)
Deletion of the amyloid precursor-like protein 1 (APLP1) enhances excitatory synaptic transmission, reduces network inhibition but does not impair synaptic plasticity in the mouse dentate gyrus
Matej Vnencak et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2015)
APLP1 and APLP2, members of the APP family of proteins, behave similarly to APP in that they associate with NMDA receptors and enhance NMDA receptor surface expression
Sarah L. Cousins et al.
JOURNAL OF NEUROCHEMISTRY (2015)
The APP Intracellular Domain Is Required for Normal Synaptic Morphology, Synaptic Plasticity, and Hippocampus-Dependent Behavior
Maja Klevanski et al.
JOURNAL OF NEUROSCIENCE (2015)
η-Secretase processing of APP inhibits neuronal activity in the hippocampus
Michael Willem et al.
NATURE (2015)
Cellular and Network Mechanisms Underlying Memory Impairment Induced by Amyloid beta Protein
Karla Salgado-Puga et al.
PROTEIN AND PEPTIDE LETTERS (2015)
APP and APLP2 interact with the synaptic release machinery and facilitate transmitter release at hippocampal synapses
Tomas Fanutza et al.
ELIFE (2015)
Acute function of secreted amyloid precursor protein fragment APPs alpha in synaptic plasticity
Meike Hick et al.
ACTA NEUROPATHOLOGICA (2015)
sAβPPα Improves Hippocampal NMDA-Dependent Functional Alterations Linked to Healthy Aging
Laura Moreno et al.
JOURNAL OF ALZHEIMERS DISEASE (2015)
Amyloid Precursor Protein Knockout Diminishes Synaptic Vesicle Proteins at the Presynaptic Active Zone in Mouse Brain
Melanie Laßek et al.
Current Alzheimer Research (2014)
Regulation of Presynaptic Ca2+, Synaptic Plasticity and Contextual Fear Conditioning by a N-terminal β-Amyloid Fragment
James L. M. Lawrence et al.
JOURNAL OF NEUROSCIENCE (2014)
Amyloid Precursor Protein Dimerization and Synaptogenic Function Depend on Copper Binding to the Growth Factor-Like Domain
Frederik Baumkoetter et al.
JOURNAL OF NEUROSCIENCE (2014)
The Amyloid Precursor Protein Controls Adult Hippocampal Neurogenesis through GABAergic Interneurons
Baiping Wang et al.
JOURNAL OF NEUROSCIENCE (2014)
Intracellular Accumulation of Amyloid-β (Aβ) Protein Plays a Major Role in Aβ-Induced Alterations of Glutamatergic Synaptic Transmission and Plasticity
Cristian Ripoli et al.
JOURNAL OF NEUROSCIENCE (2014)
Genetic Suppression of Transgenic APP Rescues Hypersynchronous Network Activity in a Mouse Model of Alzeimer's Disease
Heather A. Born et al.
JOURNAL OF NEUROSCIENCE (2014)
Differential role of APP and APLPs for neuromuscular synaptic morphology and function
Maja Klevanski et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2014)
APP Is Cleaved by Bace1 in Pre-Synaptic Vesicles and Establishes a Pre-Synaptic Interactome, via Its Intracellular Domain, with Molecular Complexes that Regulate Pre-Synaptic Vesicles Functions
Dolores Del Prete et al.
PLOS ONE (2014)
Shedding of APP limits its synaptogenic activity and cell adhesion properties
Ronny Stahl et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2014)
Holo-APP and G-protein-mediated signaling are required for sAPPα-induced activation of the Akt survival pathway
N. Milosch et al.
CELL DEATH & DISEASE (2014)
APP Homodimers Transduce an Amyloid-β-Mediated Increase in Release Probability at Excitatory Synapses
Hilla Fogel et al.
CELL REPORTS (2014)
Dynamic learning and memory, synaptic plasticity and neurogenesis: an update
Ales Stuchlik
FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2014)
Comparative analysis of single and combined APP/APLP knockouts reveals reduced spine density in APP-KO mice that is prevented by APPsa expression
Sascha W. Weyer et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2014)
Time-dependent changes in gene expression induced by secreted amyloid precursor protein-alpha in the rat hippocampus
Margaret M. Ryan et al.
BMC GENOMICS (2013)
Soluble amyloid-β precursor protein binds its cell surface receptor in a cooperative fashion with glypican and syndecan proteoglycans
Constanze Reinhard et al.
JOURNAL OF CELL SCIENCE (2013)
Amyloid precursor proteins are constituents of the presynaptic active zone
Melanie Lassek et al.
JOURNAL OF NEUROCHEMISTRY (2013)
Postnatal Disruption of the Disintegrin/Metalloproteinase ADAM10 in Brain Causes Epileptic Seizures, Learning Deficits, Altered Spine Morphology, and Defective Synaptic Functions
Johannes Prox et al.
JOURNAL OF NEUROSCIENCE (2013)
Roles of the amyloid precursor protein family in the peripheral nervous system
John H. Caldwell et al.
MECHANISMS OF DEVELOPMENT (2013)
ENHANCEMENT OF LONG-TERM DEPRESSION BY SOLUBLE AMYLOID β PROTEIN IN RAT HIPPOCAMPUS IS MEDIATED BY METABOTROPIC GLUTAMATE RECEPTOR AND INVOLVES ACTIVATION OF P38MAPK, STEP AND CASPASE-3
X. Chen et al.
NEUROSCIENCE (2013)
Soluble Alpha-APP (sAPPalpha) Regulates CDK5 Expression and Activity in Neurons
Daniela Hartl et al.
PLOS ONE (2013)
Soluble β-amyloid Precursor Protein Alpha Binds to p75 Neurotrophin Receptor to Promote Neurite Outgrowth
Noriko Hasebe et al.
PLOS ONE (2013)
D-Amino acids in brain neurotransmission and synaptic plasticity
Jean-Marie Billard
AMINO ACIDS (2012)
APP physiological and pathophysiological functions: insights from animal models
Qinxi Guo et al.
CELL RESEARCH (2012)
APP dimer formation is initiated in the endoplasmic reticulum and differs between APP isoforms
Simone Isbert et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2012)
Role of APP and Aβ in Synaptic Physiology
Zilai Wang et al.
CURRENT ALZHEIMER RESEARCH (2012)
ß-Site APP-cleaving enzyme 1 trafficking and Alzheimer's disease pathogenesis
Jiangli Tan et al.
JOURNAL OF NEUROCHEMISTRY (2012)
Deletion of the amyloid precursor-like protein 2 (APLP2) does not affect hippocampal neuron morphology or function
Brea Midthune et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2012)
Amyloid precursor protein (APP) regulates synaptic structure and function
Sheue-Houy Tyan et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2012)
Reduction of Hippocampal Hyperactivity Improves Cognition in Amnestic Mild Cognitive Impairment
Arnold Bakker et al.
NEURON (2012)
Physiological Functions of APP Family Proteins
Ulrike C. Mueller et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)
Neurotoxicity of Amyloid β-Protein: Synaptic and Network Dysfunction
Lennart Mucke et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)
The role of APP and APLP for synaptic transmission, plasticity, and network function: lessons from genetic mouse models
Martin Korte et al.
EXPERIMENTAL BRAIN RESEARCH (2012)
Roles of amyloid precursor protein family members in neuroprotection, stress signaling and aging
Donat Koegel et al.
EXPERIMENTAL BRAIN RESEARCH (2012)
Structural aspects and physiological consequences of APP/APLP trans-dimerization
Frederik Baumkoetter et al.
EXPERIMENTAL BRAIN RESEARCH (2012)
Functions of the APP gene family in the nervous system: insights from mouse models
Dorothee Aydin et al.
EXPERIMENTAL BRAIN RESEARCH (2012)
Consequences of Inhibiting Amyloid Precursor Protein Processing Enzymes on Synaptic Function and Plasticity
Hui Wang et al.
NEURAL PLASTICITY (2012)
APP and APLP2 are essential at PNS and CNS synapses for transmission, spatial learning and LTP
Sascha W. Weyer et al.
EMBO JOURNAL (2011)
Role of Key Aromatic Residues in the Ligand-binding Domain of α7 Nicotinic Receptors in the Agonist Action of β-Amyloid
Mei Tong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
A novel pathway for amyloid precursor protein processing
Erik Portelius et al.
NEUROBIOLOGY OF AGING (2011)
Identification of NEEP21 as a β-Amyloid Precursor Protein-Interacting Protein In Vivo That Modulates Amyloidogenic Processing In Vitro
Eric M. Norstrom et al.
JOURNAL OF NEUROSCIENCE (2010)
BETA AMYLOID-INDEPENDENT ROLE OF AMYLOID PRECURSOR PROTEIN IN GENERATION AND MAINTENANCE OF DENDRITIC SPINES
K. J. Lee et al.
NEUROSCIENCE (2010)
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
Hongmei Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Amyloid precursor protein and its homologues: a family of proteolysis-dependent receptors
Kristin T. Jacobsen et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2009)
Subcellular localization and dimerization of APLP1 are strikingly different from APP and APLP2
Daniela Kaden et al.
JOURNAL OF CELL SCIENCE (2009)
Amyloid Precursor Protein Regulates Cav1.2 L-type Calcium Channel Levels and Function to Influence GABAergic Short-Term Plasticity
Li Yang et al.
JOURNAL OF NEUROSCIENCE (2009)
Amyloid β-Induced Neuronal Hyperexcitability Triggers Progressive Epilepsy
Rimante Minkeviciene et al.
JOURNAL OF NEUROSCIENCE (2009)
Amyloid-β as a positive endogenous regulator of release probability at hippocampal synapses
Efrat Abramov et al.
NATURE NEUROSCIENCE (2009)
Soluble Oligomers of Amyloid β Protein Facilitate Hippocampal Long-Term Depression by Disrupting Neuronal Glutamate Uptake
Shaomin Li et al.
NEURON (2009)
Secreted amyloid precursor protein-α upregulates synaptic protein synthesis by a protein kinase G-dependent mechanism
Ana M. Claasen et al.
NEUROSCIENCE LETTERS (2009)
TiGER: A database for tissue-specific gene expression and regulation
Xiong Liu et al.
BMC BIOINFORMATICS (2008)
Activity requires soluble amyloid precursor protein α to promote neurite outgrowth in neural stem cell-derived neurons via activation of the MAPK pathway
Nidhi Gakhar-Koppole et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2008)
Amyloid Precursor Protein Trafficking, Processing, and Function
Gopal Thinakaran et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Picomolar Amyloid-β Positively Modulates Synaptic Plasticity and Memory in Hippocampus
Daniela Puzzo et al.
JOURNAL OF NEUROSCIENCE (2008)
Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
Ganesh M. Shankar et al.
NATURE MEDICINE (2008)
Endogenous secreted amyloid precursor protein-α regulates hippocampal NMDA receptor function, long-term potentiation and spatial memory
Chanel J. Taylor et al.
NEUROBIOLOGY OF DISEASE (2008)
Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer's disease
Marc Aurel Busche et al.
SCIENCE (2008)
Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease
Jorge J. Palop et al.
NEURON (2007)
The secreted β-amyloid precursor protein ectodomain APPsα is sufficient to rescue the anatomical, behavioral, and electrophysiological abnormalities of APP-deficient mice
Sabine Ring et al.
JOURNAL OF NEUROSCIENCE (2007)
The APP family of proteins: similarities and differences
D. M. Walsh et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2007)
Electrophysiological and cerebrovascular effects of the α-secretase-derived form of amyloid precursor protein in young and middle-aged rats
Manuel Sanchez-Alavez et al.
BRAIN RESEARCH (2007)
Molecular dissection of the interaction between amyloid precursor protein and its neuronal trafficking receptor SorLA/LR11
OM Andersen et al.
BIOCHEMISTRY (2006)
Alzheimer precursor protein interaction with the Nogo-66 receptor reduces amyloid-β plaque deposition
JH Park et al.
JOURNAL OF NEUROSCIENCE (2006)
Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development
S Guénette et al.
EMBO JOURNAL (2006)
Homo- and heterodimerization of APP family members promotes intercellular adhesion
P Soba et al.
EMBO JOURNAL (2005)
Defective neuromuscular synapses in mice lacking amyloid precursor protein (APP) and APP-like protein 2
P Wang et al.
JOURNAL OF NEUROSCIENCE (2005)
The proteolytic processing of the amyloid precursor protein gene family members APLP-1 and APLP-2 involves α-, β-, γ-, and ε-like cleavages -: Modulation of APLP-1 processing by N-glycosylation
S Eggert et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Hyperexcitability induced by GABA withdrawal facilitates hippocampal long-term potentiation
C Casasola et al.
NEUROSCIENCE (2004)
Transient and sustained types of long-term potentiation in the CA1 area of the rat hippocampus
A Volianskis et al.
JOURNAL OF PHYSIOLOGY-LONDON (2003)
Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory
PR Turner et al.
PROGRESS IN NEUROBIOLOGY (2003)
Alzheimer's disease is a synaptic failure
DJ Selkoe
SCIENCE (2002)
The role of the low-density lipoprotein receptor-related protein (LRP1) in Alzheimer's Aβ generation
JJ Goto et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2002)
Phosphatidylinositol-3-kinase-Akt kinase and p42/p44 mitogen-activated protein kinases mediate neurotrophic and excitoprotective actions of a secreted form of amyloid precursor protein
GJ Cheng et al.
EXPERIMENTAL NEUROLOGY (2002)
A physiologic signaling role for the γ-secretase-derived intracellular fragment of APP
MA Leissring et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Neuroscience - The molecular biology of memory storage: A dialogue between genes and synapses
ER Kandel
SCIENCE (2001)
A transcriptively active complex of APP with Fe65 and histone acetyltransferase Tip60
XW Cao et al.
SCIENCE (2001)
Similar levels of long-term potentiation in amyloid precursor protein-null and wild-type mice in the CA1 region of picrotoxin treated slices
SM Fitzjohn et al.
NEUROSCIENCE LETTERS (2000)