期刊
AGING AND DISEASE
卷 8, 期 5, 页码 590-610出版社
INT SOC AGING & DISEASE
DOI: 10.14336/AD.2017.0430
关键词
vascular aging; vascular remodeling; endothelial dysfunction; arterial stiffness
资金
- China Scholarship Council [201406320118]
- American Heart Association [15PRE25700416]
- Sigma Xi [G201503151162287]
- National Natural Science Foundation of China [81301996]
- Ph.D. Programs Foundation of Ministry of Education of China [20130101120017]
Among age-related diseases, cardiovascular and cerebrovascular diseases are major causes of death. Vascular dysfunction is a key characteristic of these diseases wherein age is an independent and essential risk factor. The present work will review morphological alterations of aging vessels in-depth, which includes the discussion of age-related microvessel loss and changes to vasculature involving the capillary basement membrane, intima, media, and adventitia as well as the accompanying vascular dysfunctions arising from these alterations.
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