期刊
PATHOGENS AND DISEASE
卷 75, 期 3, 页码 -出版社
OXFORD UNIV PRESS
DOI: 10.1093/femspd/ftx029
关键词
Candida; colonization; respiratory tract
资金
- NHLBI NIH HHS [K23 HL130641] Funding Source: Medline
Candida is an opportunistic pathogen and the most commonly isolated fungal genus in humans. Though Candida is often detected in respiratory specimens from humans with and without lung disease, its significance remains undetermined. While historically considered a commensal organism with low virulence potential, the status of Candida as an innocent bystander has recently been called into question by both clinical observations and animal experimentation. We here review what is currently known and yet to be determined about the clinical, microbiological and pathophysiological significance of the detection of Candida spp. in the human respiratory tract.
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