期刊
EUROPEAN JOURNAL OF RADIOLOGY
卷 84, 期 7, 页码 1259-1268出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.ejrad.2015.03.017
关键词
Immunotherapy; Cancer; Oncologic imaging; Drug toxicity; Tumor response assessment
资金
- NCI [1K23CA157631]
The recent advances in the clinical application of anti-cancer immunotherapeutic agents have opened a new arena for the treatment of advanced cancers. Cancer immunotherapy is associated with a variety of important radiographic features in the assessments of tumor response and immune-related adverse events, which calls for radiologists' awareness and in-depth knowledge on the topic. This article will provide the state-of-the art review and perspectives of cancer immunotherapy, including its molecular mechanisms, the strategies for immune-related response assessment on imaging and their pitfalls, and the emerging knowledge of radiologic manifestations of immune-related adverse events. The cutting edge clinical and radiologic investigations are presented to provide future directions. (C) 2015 Elsevier Ireland Ltd. All rights reserved.
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