期刊
DYES AND PIGMENTS
卷 136, 期 -, 页码 627-632出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.dyepig.2016.09.014
关键词
-
资金
- National Natural Science Foundation of China [21236002]
By fusion of HBT and hemicyanine, we have designed a novel donor-two-acceptor type fluorophore (HHC) as a platform for the detection of different kinds of guests. HHC displays an emission at 580 nm in aqueous solution and two emission bands at 450 nm and 616 nm as a result of the donor-two-acceptor feature with the existance of CTAB. The fluorescence of HHC may be readily modulated by protection/deprotection of its electron-donating hydroxyl group and response different guests. As an example, we introduced p-nitrobenzyl group, which is sensitive to Nitroreductase (NTR), to the hydroxyl group of HHC and constructed a novel selective and sensitive fluorescence probe HHCP for fast detection and intracellular imaging of nitroreductase. (C) 2016 Elsevier Ltd. All rights reserved.
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