期刊
BIOLOGICAL CHEMISTRY
卷 398, 期 1, 页码 3-22出版社
WALTER DE GRUYTER GMBH
DOI: 10.1515/hsz-2016-0204
关键词
biomaterials; click chemistry; coating; implant; multifunctional; surface chemistry
资金
- DFG [TRR67]
- European Union
- Free State of Saxony
- Graduate School BuildMoNa
A controlled interaction of materials with their surrounding biological environment is of great interest in many fields. Multifunctional coatings aim to provide simultaneous modulation of several biological signals. They can consist of various combinations of bioactive, and bioinert components as well as of reporter molecules to improve cell-material contacts, prevent infections or to analyze biochemical events on the surface. However, specific immobilization and particular assembly of various active molecules are challenging. Herein, an overview of multifunctional coatings for biomaterials is given, focusing on synthetic strategies and the biological benefits by displaying several motifs.
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