期刊
CLINICS IN GERIATRIC MEDICINE
卷 33, 期 1, 页码 87-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.cger.2016.08.007
关键词
Sjogren syndrome; Dry eye; Aging; Salivary hypofunction; Xerostomia
资金
- Bristol-Myers Squibb
- Novartis
- Intramural Research Program of the NIH, NIDCR
Dry eye and dry mouth symptoms are each reported by up to 30% of persons more than 65 years of age, particularly in women. Medication side effects are the most common contributing factors. The evaluation of these symptoms requires measures of ocular and oral dryness. Sjogren syndrome is the prototypic disease associated with dryness of the eyes and mouth and predominantly affects women in their perimenopausal and postmenopausal years. In addition to topical treatment of the mucosal dryness, patients with Sjogren syndrome may require treatment with systemic immunomodulatory and immunosuppressive agents to manage a variety of extraglandular manifestations.
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