Surface-mounted MOF templated fabrication of homochiral polymer thin film for enantioselective adsorption of drugs

A self-polymerized chiral monomer 3,4-dihydroxy-L-phenylalanine (L-DOPA) has been introduced into the pores of an achiral surface-mounted metal organic framework (SURMOF), and then the homochiral poly(L-DOPA) thin film has been successfully formed after UV light irradiation and etching of the SURMOF. Remarkably, such a poly(L-DOPA) thin film exhibited enantioselective adsorption of naproxen. This study opened a SURMOF-templated approach for preparing porous polymer thin films.