期刊
CURRENT HYPERTENSION REPORTS
卷 19, 期 2, 页码 -出版社
SPRINGER
DOI: 10.1007/s11906-017-0711-8
关键词
Cell fate; Cell identity; Cell memory; Cell number; Recruitment
资金
- NHLBI NIH HHS [R37 HL066242] Funding Source: Medline
- NIDDK NIH HHS [P50 DK096373, R01 DK091330] Funding Source: Medline
During development, renin cells are precursors for arteriolar smooth muscle, mesangial cells, and interstitial pericytes. Those seemingly differentiated descendants retain the memory to re-express renin when there is a threat to homeostasis. Understanding how such molecular memory is constructed and regulated would be crucial to comprehend cell identity which is, in turn, intimately linked to homeostasis.
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