期刊
COLLOIDS AND SURFACES B-BIOINTERFACES
卷 150, 期 -, 页码 288-296出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.colsurfb.2016.10.041
关键词
Biodegradable metals; Biomaterials; Electrochemical impedance spectroscopy; Immersion; Cell culture condition
资金
- European Union through the Warsaw University of Technology Development Programme
- JSPS KAKENHI [26282151]
- Grants-in-Aid for Scientific Research [26282151] Funding Source: KAKEN
In this research, the effect of the presence of living cells (SaOS-2) on in vitro degradation of Mg-2.0Zn-0.98Mn(ZM21) magnesium alloy was examined by two methods simple immersion/cell culture tests and electrochemical measurements (electrochemical impedance spectroscopy and potentiodynamic polarization) under cell culture conditions. In immersion/cell culture tests, when SaOS-2 cells were cultured on ZM21 samples, pH of cell culture medium decreased, therefore weight loss and Mg2+ ion release from the samples increased. Electrochemical measurements revealed the presence of living cells increased corrosion rate (I-corr) and decreased polarization resistance (R-p) after 48 h of incubation. This acceleration of ZM21 corrosion can mainly be attributed to the decrease of medium pH due to cellular metabolic activities. (C) 2016 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据