期刊
ACS APPLIED MATERIALS & INTERFACES
卷 9, 期 5, 页码 5023-5030出版社
AMER CHEMICAL SOC
DOI: 10.1021/acsami.6b15979
关键词
hydroxyapatite; composite coating; pulse electrochemical deposition; antibacteria; frictional wear
资金
- National Natural Science Foundation of China [51662038, 11572211]
- Science and Technology Innovation Project of Xinjiang Normal University [XSY201602005]
- Jiangsu Provincial Special Program of Medical Science [BL2012004]
- Jiangsu Provincial Clinical Orthopedic Center
- Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD)
Although bioinert titanium has been widely applied in orthopedics and related fields, its usage is limited by its unsatisfying osteoinductivity, anti-infection capability, and wear-resistance. Osteoinductive apatite, coating can be fabricated on a titanium surface by electrochemical methods, but this causes bacterial adhesion and poor wear-resistance. On the basis of pulse electrochemical technology, a wear-resistance and antibacterial osteoinductive coating was fabricated through codeposition of hydroxyapatite (HA) and nano-Ag effectuated by the cohybridization ofchitosan (CS) with Ag+ and Ca2+ A composite coating formed with uniformly dispersed spherical nanoparticles was obtained at optimized deposition potential, Ag concentration, and apatite concentration. The nanocomposite coating shows excellent bioinductive activity; it promotes preferential growth on the (002) face, and needle-like ordered arrangement of apatite. Due to the mediation of CS hybridization, a compact structure is achieved in the HA/Ag composite coating which significantly enhances the wear-resistance of the coating and reduces the release of Ca2+ and Ag+ The antibacterial rate of the coating on Escherichia coli and Staphylococcus aureus is up to 99% according to the antibacterial test. In conclusion, a wear-resistant and long-term antibacterial bioactive nanocomposite coating is successfully fabricated on titanium surface through the strategy established in this study.
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