期刊
AMERICAN JOURNAL OF ROENTGENOLOGY
卷 208, 期 1, 页码 131-139出版社
AMER ROENTGEN RAY SOC
DOI: 10.2214/AJR.16.16355
关键词
active surveillance; multiparametric MRI; prostate cancer
资金
- Cancer Research UK
- Engineering and Physical Sciences Research Council Imaging Centre in Cambridge
- Engineering and Physical Sciences Research Council Imaging Centre in Manchester
- NIHR Biomedical Research Centre
- Cancer Research UK [16465] Funding Source: researchfish
OBJECTIVE. Active surveillance (AS) has emerged as a management strategy for preventing overtreatment of indolent prostate cancer. Selection of patients for AS has traditionally proved challenging and resulted in 20-30% misclassification rates. MRI has potential to help overcome this limitation, broaden selection criteria to increase recruitment, and minimize the invasive nature of AS follow-up. CONCLUSION. The main issues surrounding MRI and AS are the heterogeneity of inclusion criteria, the definition of significant disease, and agreement about what constitutes radiologic progression. Prospective cohorts with MRI at enrollment and long-term follow-up are required to further address these issues.
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