期刊
FRONTIERS IN MICROBIOLOGY
卷 8, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fmicb.2017.00804
关键词
antimicrobial effect; Rubia philippinensis; (+)-lariciresinol; foodborne pathogens; scanning electron microscopy
类别
资金
- National Research Foundation of Korea [2013M3A9A5047052, 2008-2004707, 2012-0006701]
- National Research Foundation of Korea [2008-2004707] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
This study was undertaken to assess the antibacterial potential of a polyphenolic compound (+)-lariciresinol isolated from Rubia philippinensis against selected foodborne pathogens Staphylococcus aureus KCTC1621 and Escherichia coli O157:H7. (+)-Lariciresinol at the tested concentrations (250 mu g/disk) evoked a significant antibacterial effect as a diameter of inhibition zones ( 12.1-14.9 mm) with minimum inhibitory concentration ( MIC), and minimum bactericidal concentration values of 125-250 and 125-250 mu g/mL, respectively. Furthermore, (+)-lariciresinol at MIC showed reduction in bacterial cell viabilities, efflux of potassium (K+) ions and release of 260 nm materials against E. coli O157:H7 and S. aureus KCTC1621. Moreover, deteriorated cell wall morphology of E. coli O157:H7 and S. aureus KCTC1621 cells treated with (+)-lariciresinol at MIC further confirmed its inhibitory effect against the tested pathogens, suggesting it to be an alternative means of antimicrobials.
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