期刊
BIOSENSORS & BIOELECTRONICS
卷 88, 期 -, 页码 249-257出版社
ELSEVIER ADVANCED TECHNOLOGY
DOI: 10.1016/j.bios.2016.08.043
关键词
Date-rape drug; Nanocrystal GO-Zeo; Ketamine; Paper based sensor; Electro-oxidation
The present study was aimed to develop an ultrasensitive technique for electroanalysis of ketamine; a date rape drug. It involved the fabrication of nano-hybrid based electrochemical micro fluidic paper based analytical device (E mu PADs) for electrochemical sensing of ketamine. A paper chip was developed using zeolites nanoflakes and graphene-oxide nanocrystals (Zeo-GO). WAD offers many advantages such as facile approach, economical and potential for commercialization. Nanocrystal modified E mu PAD showed wide linear range 0.001-5 nM/mL and a very low detection limit of 0.001 nM/mL. The developed sensor was tested in real time samples like alcoholic and non-alcoholic drinks and found good correlation (99%). The hyphenation of E mu PAD integrated with nanocrystalline Zeo-GO for detection of ketamine has immense prospective for field-testing platforms. An extensive development could be made for industrial translation of this fabricated device. (C) 2016 Elsevier B.V. All rights reserved.
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