4.8 Article

Affimers proteins are versatile and renewable affinity reagents

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Inhibition of RAS function through targeting an allosteric regulatory site

Russell Spencer-Smith et al.

NATURE CHEMICAL BIOLOGY (2017)

Review Cardiac & Cardiovascular Systems

Lymphatic System in Cardiovascular Medicine

Aleksanteri Aspelund et al.

CIRCULATION RESEARCH (2016)

Article Biochemistry & Molecular Biology

SH2 Domains Serve as Lipid-Binding Modules for pTyr-Signaling Proteins

Mi-Jeong Park et al.

MOLECULAR CELL (2016)

Article Biochemical Research Methods

A Bayesian cluster analysis method for single-molecule localization microscopy data

Juliette Griffie et al.

NATURE PROTOCOLS (2016)

Article Multidisciplinary Sciences

Enhancement of hERG channel activity by scFv antibody fragments targeted to the PAS domain

Carol A. Harley et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Cell Biology

Nanobodies that block gating of the P2X7 ion channel ameliorate inflammation

Welbeck Danquah et al.

SCIENCE TRANSLATIONAL MEDICINE (2016)

Article Multidisciplinary Sciences

EGFR oligomerization organizes kinase-active dimers into competent signalling platforms

Sarah R. Needham et al.

NATURE COMMUNICATIONS (2016)

Review Biochemistry & Molecular Biology

Ion channel therapeutics for pain

Sarah E. Skerratt et al.

CHANNELS (2015)

Review Pharmacology & Pharmacy

Challenges and opportunities for non-antibody scaffold drugs

Rodrigo Vazquez-Lombardi et al.

DRUG DISCOVERY TODAY (2015)

Review Medicine, Research & Experimental

Specific in vivo knockdown of protein function by intrabodies

Andrea L. J. Marschall et al.

Article Biochemistry & Molecular Biology

Exploration of the HIF-1 alpha/p300 interface using peptide and Adhiron phage display technologies

Hannah F. Kyle et al.

MOLECULAR BIOSYSTEMS (2015)

Article Multidisciplinary Sciences

Crystal structures of a double-barrelled fluoride ion channel

Randy B. Stockbridge et al.

NATURE (2015)

Editorial Material Multidisciplinary Sciences

Standardize antibodies used in research

Andrew Bradbury et al.

NATURE (2015)

Article Multidisciplinary Sciences

Tissue-based map of the human proteome

Mathias Uhlen et al.

SCIENCE (2015)

Review Biotechnology & Applied Microbiology

Non-immunoglobulin scaffolds: a focus on their targets

Katja Skrlec et al.

TRENDS IN BIOTECHNOLOGY (2015)

Article Chemistry, Multidisciplinary

Phage display selected magnetite interacting Adhirons for shape controlled nanoparticle synthesis

Andrea E. Rawlings et al.

CHEMICAL SCIENCE (2015)

Review Cell Biology

Tenascin C in metastasis: A view from the invasive front

Camille M. Lowy et al.

CELL ADHESION & MIGRATION (2015)

Article Chemistry, Multidisciplinary

Trivalent Gd-DOTA reagents for modification of proteins

Martin J. Fisher et al.

RSC ADVANCES (2015)

Article Biochemistry & Molecular Biology

Adhiron: a stable and versatile peptide display scaffold for molecular recognition applications

Christian Tiede et al.

PROTEIN ENGINEERING DESIGN & SELECTION (2014)

Article Chemistry, Multidisciplinary

Antibody therapeutics targeting ion channels: are we there yet?

Han Sun et al.

ACTA PHARMACOLOGICA SINICA (2013)

Article Multidisciplinary Sciences

Dissection of the BCR-ABL signaling network using highly specific monobody inhibitors to the SHP2 SH2 domains

Fern Sha et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Biochemistry & Molecular Biology

Targeting Extracellular Domains D4 and D7 of Vascular Endothelial Growth Factor Receptor 2 Reveals Allosteric Receptor Regulatory Sites

Caroline A. C. Hyde et al.

MOLECULAR AND CELLULAR BIOLOGY (2012)

Article Cell Biology

Midbody assembly and its regulation during cytokinesis

Chi-Kuo Hu et al.

MOLECULAR BIOLOGY OF THE CELL (2012)

Article Neurosciences

Positive allosteric modulation of TRPV1 as a novel analgesic mechanism

Evan E. Lebovitz et al.

MOLECULAR PAIN (2012)

Article Biochemical Research Methods

A simple, versatile method for GFP-based super-resolution microscopy via nanobodies

Jonas Ries et al.

NATURE METHODS (2012)

Editorial Material Biochemical Research Methods

European and international collaboration in affinity proteomics

Oda Stoevesandt et al.

NEW BIOTECHNOLOGY (2012)

Article Multidisciplinary Sciences

Structural and functional analysis of phosphorylation-specific binders of the kinase ERK from designed ankyrin repeat protein libraries

Lutz Kummer et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Pharmacology & Pharmacy

Small Molecule Positive Allosteric Modulation of TRPV1 Activation by Vanilloids and Acidic pH

Krisztian Kaszas et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2012)

Article Biochemistry & Molecular Biology

Targeting the SH2-Kinase Interface in Bcr-Abl Inhibits Leukemogenesis

Florian Grebien et al.

Article Biophysics

Automated multidimensional single molecule fluorescence microscopy feature detection and tracking

Daniel J. Rolfe et al.

EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS (2011)

Article Biochemistry & Molecular Biology

Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs

Thordur Oskarsson et al.

NATURE MEDICINE (2011)

Article Biochemical Research Methods

A roadmap to generate renewable protein binders to the human proteome

Karen Colwill et al.

NATURE METHODS (2011)

Article Biochemical Research Methods

Direct stochastic optical reconstruction microscopy with standard fluorescent probes

Sebastian van de Linde et al.

NATURE PROTOCOLS (2011)

Article Biochemistry & Molecular Biology

Structurefunction studies of an engineered scaffold protein derived from Stefin A. II: Development and applications of the SQT variant

Lukas Kurt Josef Stadler et al.

PROTEIN ENGINEERING DESIGN & SELECTION (2011)

Review Biochemical Research Methods

Antibody validation

Jennifer Bordeaux et al.

BIOTECHNIQUES (2010)

Article Biochemistry & Molecular Biology

Cell Signaling by Receptor Tyrosine Kinases

Mark A. Lemmon et al.

Article Biochemistry & Molecular Biology

A potent and highly specific FN3 monobody inhibitor of the Abl SH2 domain

John Wojcik et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)

Article Biochemistry & Molecular Biology

Generating a panel of highly specific antibodies to 20 human SH2 domains by phage display

K. Pershad et al.

PROTEIN ENGINEERING DESIGN & SELECTION (2010)

Article Chemistry, Multidisciplinary

Super-Resolution Imaging with Small Organic Fluorophores

Mike Heilemann et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)

Article Chemistry, Multidisciplinary

Subdiffraction-resolution fluorescence imaging with conventional fluorescent probes

Mike Heilemann et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2008)

Review Biochemical Research Methods

A Genecentric Human Protein Atlas for Expression Profiles Based on Antibodies

Lisa Berglund et al.

MOLECULAR & CELLULAR PROTEOMICS (2008)

Review Biochemistry & Molecular Biology

Chaperone-Assisted Crystallography with DARPins

Gaby Sennhauser et al.

STRUCTURE (2008)

Article Multidisciplinary Sciences

Dual-color superresolution imaging of genetically expressed probes within individual adhesion complexes

Hari Shroff et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Biochemical Research Methods

ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome

Michael J. Taussig et al.

NATURE METHODS (2007)

Article Biotechnology & Applied Microbiology

Opinion - How many drug targets are there?

John P. Overington et al.

NATURE REVIEWS DRUG DISCOVERY (2006)

Article Biochemical Research Methods

Targeting and tracing antigens in live cells with fluorescent nanobodies

Ulrich Rothbauer et al.

NATURE METHODS (2006)

Article Biochemical Research Methods

A human protein atlas for normal and cancer tissues based on antibody proteomics

M Uhlén et al.

MOLECULAR & CELLULAR PROTEOMICS (2005)

Article Multidisciplinary Sciences

Genes that mediate breast cancer metastasis to lung

AJ Minn et al.

NATURE (2005)

Review Oncology

The phosphatidylinositol 3-kinase-AKT pathway in human cancer

I Vivanco et al.

NATURE REVIEWS CANCER (2002)

Review Biochemistry & Molecular Biology

Stability engineering of antibody single-chain Fv fragments

A Wörn et al.

JOURNAL OF MOLECULAR BIOLOGY (2001)

Article Biochemistry & Molecular Biology

A novel type of receptor protein, based on the lipocalin scaffold, with specificity for digoxigenin

S Schlehuber et al.

JOURNAL OF MOLECULAR BIOLOGY (2000)