期刊
CHEMICAL COMMUNICATIONS
卷 53, 期 17, 页码 2618-2621出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6cc08978j
关键词
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资金
- National Natural Science Foundation of China [81571799, 21202147]
- Natural Science Foundation of Zhejiang Province [LY13H090013, LQ14B020003]
We here provide the first report on the construction of nanoparticles formulating highly potent cytotoxic therapeutics using albumin. Maytansinoid DM1 can be efficiently integrated into albumin nanoparticles, resulting in remarkable alleviation of in vivo drug toxicity and expanding the repertoire of albumin technology available for cancer therapy.
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