期刊
ASIAN JOURNAL OF PSYCHIATRY
卷 25, 期 -, 页码 188-190出版社
ELSEVIER
DOI: 10.1016/j.ajp.2016.11.002
关键词
Chlorpromazine; Cataract; Corneal deposits; Visual impairment; Switch over
类别
Chlorpromazine is a low potency typical antipsychotic agent used to treat schizophrenia. It continues to be prescribed frequently in India owing to its lower cost. There have been previous reports of ocular adverse effects with prolonged use of chlorpromazine. We report three patients who developed corneal and lenticular opacities secondary to prolonged chlorpromazine use leading to visual impairment. Early detection of ocular deposits and switching over to risperidone from chlorpromazine helped in the reversal of chlorpromazine-induced ocular side effects in one of them. The case series further adds evidence to the causative relationship between chlorpromazine and ocular side effects. (C) 2016 Elsevier B.V. All rights reserved.
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