期刊
ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY
卷 46, 期 4, 页码 861-871出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/21691401.2017.1345930
关键词
Indigofera tinctoria; green synthesis; anticancer; antimicrobial; antioxidant; catalysis
资金
- University Grants Commission (UGC), Government of India
This study reports the synthesis of noble metal nanoparticles, namely silver and gold from their respective salt by leaf extract of a medicinal plant Indigofera tinctoria. This leaf extract plays a dual role as stabilizing and reducing agent for the formation of nanoparticles. The synthesized silver and gold nanoparticles were characterized by UV-vis. spectroscopy, FTIR spectroscopy, XRD, TEM, EDX and AFM analysis. All these techniques confirm the formation of crystalline nanoparticles. The cytotoxic effect of I. tinctoria leaf extract and the nanoparticles were studied on lung cancer cell line A549. It was shown that the cell viability decreases with increasing concentration and nanoparticles has more toxic effect on cancer cell than the pure leaf extract. IC50 value of I. tinctoria leaf extract, AuNP and AgNP respectively, are 71.92 +/- 0.76 mu g/ml, 59.33 +/- 0.57 mu g/ml and 56.62 +/- 0.86 mu g/ml. Antimicrobial activities were tested against both bacterial and fungal strains by agar well diffusion method. The synthesized nanoparticles show high antimicrobial activities towards all tested microbial strains with varying degree. The antioxidant activities of synthesized nanoparticles were analysed by using DPPH method and found that nanoparticles show higher antioxidant activities than the leaf extract. Outstanding catalytic activities of nanoparticles were demonstrated by employing the reduction reactions of o/p-niroanilines by NaBH4.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据