期刊
JOURNAL OF INTENSIVE CARE
卷 5, 期 -, 页码 -出版社
BMC
DOI: 10.1186/s40560-016-0200-1
关键词
Coagulopathy; Disseminated intravascular coagulation; Fibrinolysis; Massive bleeding; Transfusion; Fibrinogen; Trauma
In severe trauma patients, coagulopathy is frequently observed in the acute phase of trauma. Trauma-induced coagulopathy is coagulopathy caused by the trauma itself. The pathophysiology of trauma-induced coagulopathy consists of coagulation activation, hyperfibrino(geno)lysis, and consumption coagulopathy. These pathophysiological mechanisms are the characteristics to DIC with the fibrinolytic phenotype.
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