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Marine actinobacteria as a drug treasure house

期刊

BIOMEDICINE & PHARMACOTHERAPY
卷 87, 期 -, 页码 46-57

出版社

ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.biopha.2016.12.086

关键词

Marine actinobacteria; Anticancer activity; Anti-inflammatory activity; Bio medicinal molecules; Medicines; Chemical structures

资金

  1. Marine scholarship Council of China

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Marine actinobacteria have been considered as a gold mine with respect to great potential regarding their secondary metabolites. Most of the researches have been conducted on actinobacteria's derived secondary metabolites to examine its pharmacological properties. Actinobacteria have a potential to provide future drugs against crucial diseases, such as drug-resistance bacteria, cancer, a range of viral illnesses, malaria, several infections and inflammations. Although, the mode of action of many bio molecules are still untapped, for a tangible number of compounds by which they interfere with human pathogenesis are reported here with detailed diagrammed illustrations. This knowledge is one of the basic vehicles to be known especially for transforming bio medicinal molecules to medicines. Actinobacteria produce a different kind of biochemical substances with numerous carbon skeletons, which have been found to be the main component interfering with human pathogenesis at different sites. Different diseases have the capability to fight at different sites inside the body can lead to a new wave of increasing the chances to produce targeted medicines. (C) 2016 Elsevier Masson SAS. All rights reserved.

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