期刊
STEM CELLS TRANSLATIONAL MEDICINE
卷 6, 期 8, 页码 1730-1739出版社
WILEY
DOI: 10.1002/sctm.17-0055
关键词
Stem cells; Cellular therapy; Clinical trials; Clinical translation; Extracellular vesicles; Therapeutics; Exosomes; Microvesicles
资金
- NIDA NIH HHS [R01 DA040385] Funding Source: Medline
Growing interest in extracellular vesicles (EVs, including exosomes and microvesicles) as therapeutic entities, particularly in stem cell-related approaches, has underlined the need for standardization and coordination of development efforts. Members of the International Society for Extracellular Vesicles and the Society for Clinical Research and Translation of Extracellular Vesicles Singapore convened a Workshop on this topic to discuss the opportunities and challenges associated with development of EV-based therapeutics at the preclinical and clinical levels. This review outlines topic-specific action items that, if addressed, will enhance the development of best-practice models for EV therapies.
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