期刊
CHEMISTRY LETTERS
卷 46, 期 4, 页码 533-535出版社
CHEMICAL SOC JAPAN
DOI: 10.1246/cl.161172
关键词
Polyoxometalate (POM); Liposome collapse activity; Cytotoxicity
资金
- Nippon Sheet Glass Foundation for Materials Science and Engineering
- Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan [26600021, 16H04092]
- Grants-in-Aid for Scientific Research [16H04092, 26600021] Funding Source: KAKEN
We report the structure-dependent effects of polyoxometalate (POM), a bioactive cluster material, on liposome collapse activity. Structure and lacunary state of POM were found to have a critical role to govern the efficiency and kinetics of the collapse of model cell membranes. Keggin-type POM demonstrated fast collapse activity, but with different efficiencies dependent on the lacunary state. Furthermore, an increase in POM size changed its kinetic properties, from fast to delayed activity. This kinetic transition is discussed in terms of the energy barrier during the collapse process.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据