期刊
PROTEIN & CELL
卷 8, 期 11, 页码 796-800出版社
HIGHER EDUCATION PRESS
DOI: 10.1007/s13238-017-0467-6
关键词
lipid droplet; conserved organelle; lipid metabolism; nucleic acid handling
类别
资金
- Ministry of Science and Technology of China [2016YFA0500100]
- National Natural Science Foundation of China [U1402225, 31571388, 61273228, 81270932]
- Chinese Academy of Sciences [XDA12030201]
The lipid droplet (LD) is a unique multi-functional organelle that contains a neutral lipid core covered with a phospholipid monolayer membrane. The LDs have been found in almost all organisms from bacteria to humans with similar shape. Several conserved functions of LDs have been revealed by recent studies, including lipid metabolism and trafficking, as well as nucleic acid binding and protection. We summarized these findings and proposed a hypothesis that the LD is a conserved organelle.
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