相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。C-Terminal Charge-Reversal Derivatization and Parallel Use of Multiple Proteases Facilitates Identification of Protein C-Termini by C-Terminomics
Prasath Somasundaram et al.
JOURNAL OF PROTEOME RESEARCH (2016)
The IL-6/gp130/STAT3 signaling axis: recent advances towards specific inhibition
Christoph Garbers et al.
CURRENT OPINION IN IMMUNOLOGY (2015)
Shedding of Endogenous Interleukin-6 Receptor (IL-6R) Is Governed by A Disintegrin and Metalloproteinase (ADAM) Proteases while a Full-length IL-6R Isoform Localizes to Circulating Microvesicles
Neele Schumacher et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
A systematic study of modulation of ADAM-mediated ectodomain shedding by site-specific O-glycosylation
Christoffer K. Goth et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Cytokines as Therapeutic Targets in Rheumatoid Arthritis and Other Inflammatory Diseases
Stefan Siebert et al.
PHARMACOLOGICAL REVIEWS (2015)
The interleukin-6 receptor Asp358Ala single nucleotide polymorphism rs2228145 confers increased proteolytic conversion rates by ADAM proteases
Christoph Garbers et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2014)
Interleukin-6 and its receptors: A highly regulated and dynamic system
Janina Wolf et al.
CYTOKINE (2014)
A Disintegrin and Metalloprotease 17 Dynamic Interaction Sequence, the Sweet Tooth for the Human Interleukin 6 Receptor
Stefan Duesterhoeft et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
LC-MS Based Cleavage Site Profiling of the Proteases ADAM10 and ADAM17 Using Proteome-Derived Peptide Libraries
Joanna Tucher et al.
JOURNAL OF PROTEOME RESEARCH (2014)
MEROPS: the database of proteolytic enzymes, their substrates and inhibitors
Neil D. Rawlings et al.
NUCLEIC ACIDS RESEARCH (2014)
Interleukin-6: From basic biology to selective blockade of pro-inflammatory activities
Juergen Scheller et al.
SEMINARS IN IMMUNOLOGY (2014)
Interleukin-6 and interleukin-11: same same but different
Christoph Garbers et al.
BIOLOGICAL CHEMISTRY (2013)
Minimal Interleukin 6 (IL-6) Receptor Stalk Composition for IL-6 Receptor Shedding and IL-6 Classic Signaling
Paul Baran et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Interleukin-6 Receptor Polymorphism Is Prevalent in HIV-negative Castleman Disease and Is Associated with Increased Soluble Interleukin-6 Receptor Levels
Katie Stone et al.
PLOS ONE (2013)
Convergent Solid-Phase Synthesis of N-Glycopeptides Facilitated by Pseudoprolines at Consensus-Sequence Ser/Thr Residues
Vera Ullmann et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)
Plasticity and cross-talk of Interleukin 6-type cytokines
Christoph Garbers et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2012)
The membrane-proximal domain of A Disintegrin and Metalloprotease 17 (ADAM17) is responsible for recognition of the interleukin-6 receptor and interleukin-1 receptor II
Inken Lorenzen et al.
FEBS LETTERS (2012)
Discovery of Novel Inhibitors of a Disintegrin and Metalloprotease 17 (ADAM17) Using Glycosylated and Non-glycosylated Substrates
Dmitriy Minond et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies
Nadeem Sarwar et al.
LANCET (2012)
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis
Daniel I. Swerdlow et al.
LANCET (2012)
The pro- and anti-inflammatory properties of the cytokine interleukin-6
Juergen Scheller et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2011)
Species Specificity of ADAM10 and ADAM17 Proteins in Interleukin-6 (IL-6) Trans-signaling and Novel Role of ADAM10 in Inducible IL-6 Receptor Shedding
Christoph Garbers et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Inhibition of Classic Signaling Is a Novel Function of Soluble Glycoprotein 130 (sgp130), Which Is Controlled by the Ratio of Interleukin 6 and Soluble Interleukin 6 Receptor
Christoph Garbers et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling
Simon A. Jones et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
The response of interleukin-6 and soluble interleukin-6 receptor isoforms following intermittent high intensity and continuous moderate intensity cycling
Melanie Leggate et al.
CELL STRESS & CHAPERONES (2010)
Chemoenzymatic synthesis of glycosylphosphatidylinositol-anchored glycopeptides
Zhimeng Wu et al.
CHEMICAL COMMUNICATIONS (2010)
N-Linked Glycosylation Is Essential for the Stability but Not the Signaling Function of the Interleukin-6 Signal Transducer Glycoprotein 130
Georg H. Waetzig et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Study of On-Resin Convergent Synthesis of N-Linked Glycopeptides Containing a Large High Mannose N-Linked Oligosaccharide
Rui Chen et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)
Forced Homo- and Heterodimerization of All gp130-Type Receptor Complexes Leads to Constitutive Ligand-independent Signaling and Cytokine-independent Growth
Jan Suthaus et al.
MOLECULAR BIOLOGY OF THE CELL (2010)
A common variant of the interleukin 6 receptor (IL-6r) gene increases IL-6r and IL-6 levels, without other inflammatory effects
S. Rafiq et al.
GENES AND IMMUNITY (2007)
Apoptosis is a natural stimulus of IL6R shedding and contributes to the proinflammatory trans-signaling function of neutrophils
Athena Chalaris et al.
BLOOD (2007)
Sleep enhances IL-6 trans-signaling in humans
Stoyan Dimitrov et al.
FASEB JOURNAL (2006)
N-linked oligosaccharides as outfitters for glycoprotein folding, form and function
N Mitra et al.
TRENDS IN BIOCHEMICAL SCIENCES (2006)
Abrogation of viral interleukin-6 (vIL-6)-induced signaling by intracellular retention and neutralization of vIL-6 with an anti-vIL-6 single-chain antibody selected by phage display
Marina Kovaleva et al.
JOURNAL OF VIROLOGY (2006)
Dynamics of the gp130 cytokine complex:: A model for assembly on the cellular membrane
A Schroers et al.
PROTEIN SCIENCE (2005)
Polymorphisms in the IL-6 receptor (IL-6R) gene: strong evidence that serum levels of soluble IL-6R are genetically influenced
JC Galicia et al.
GENES AND IMMUNITY (2004)
Cellular cholesterol depletion triggers shedding of the human interleukin-6 receptor by ADAM10 and ADAM17 (TACE)
V Matthews et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Hexameric structure and assembly of the interleukin-6/IL-6 α-receptor/gp130 complex
MJ Boulanger et al.
SCIENCE (2003)
The tumor necrosis factor-α converting enzyme (TACE):: A unique metalloproteinase with highly defined substrate selectivity
MJ Mohan et al.
BIOCHEMISTRY (2002)
Enhanced transgene expression in primitive hematopoietic progenitor cells and embryonic stem cells efficiently transduced by optimized retroviral hybrid vectors
R Ketteler et al.
GENE THERAPY (2002)