相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。SHARPIN regulates collagen architecture and ductal outgrowth in the developing mouse mammary gland
Emilia Peuhu et al.
EMBO JOURNAL (2017)
The Linear Ubiquitin Chain Assembly Complex Acts as a Liver Tumor Suppressor and Inhibits Hepatocyte Apoptosis and Hepatitis
Yutaka Shimizu et al.
HEPATOLOGY (2017)
Structural Insights into Linear Tri-ubiquitin Recognition by A20-Binding Inhibitor of NF-κB, ABIN-2
Shan-Meng Lin et al.
STRUCTURE (2017)
MALT1 cleaves the E3 ubiquitin ligase HOIL-1 in activated T cells, generating a dominant negative inhibitor of LUBAC-induced NF-κB signaling
Lynn Elton et al.
FEBS JOURNAL (2016)
An Essential Rote for SHARPIN in the Regulation of Caspase 1 Activity in Sepsis
Madalina-Viviana Nastase et al.
AMERICAN JOURNAL OF PATHOLOGY (2016)
Lys63/Met1-hybrid ubiquitin chains are commonly formed during the activation of innate immune signalling
Christoph H. Emmerich et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)
Targeting Non-proteolytic Protein Ubiquitination for the Treatment of Diffuse Large B Cell Lymphoma
Yibin Yang et al.
CANCER CELL (2016)
The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
Rune Busk Damgaard et al.
CELL (2016)
Molecular insights into RBR E3 ligase ubiquitin transfer mechanisms
Katja K. Dove et al.
EMBO REPORTS (2016)
Linear ubiquitination by LUBEL has a role in Drosophila heat stress response
Tomoko Asaoka et al.
EMBO REPORTS (2016)
SPATA2 promotes CYLD activity and regulates TNF-induced NF-κB signaling and cell death
Lisa Schlicher et al.
EMBO REPORTS (2016)
The paracaspase MALT1 dampens NF-B signalling by cleaving the LUBAC subunit HOIL-1
Stephan Hailfinger et al.
FEBS JOURNAL (2016)
Ubiquitination of the Transcription Factor IRF-3 Activates RIPA, the Apoptotic Pathway that Protects Mice from Viral Pathogenesis
Saurabh Chattopadhyay et al.
IMMUNITY (2016)
Molecular Determinants of Scaffold-induced Linear Ubiquitinylation of B Cell Lymphoma/Leukemia 10 (Bcl10) during T Cell Receptor and Oncogenic Caspase Recruitment Domain-containing Protein 11 (CARD11) Signaling
Yong-Kang Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
The paracaspase MALT1 cleaves the LUBAC subunit HOIL1 during antigen receptor signaling
Tiphaine Douanne et al.
JOURNAL OF CELL SCIENCE (2016)
LUBAC deficiency perturbs TLR3 signaling to cause immunodeficiency and autoinflammation
Julia Zinngrebe et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2016)
Regulation of Linear Ubiquitin Chain Assembly Complex by Caspase-Mediated Cleavage of RNF31
Donghyun Joo et al.
MOLECULAR AND CELLULAR BIOLOGY (2016)
Differential Involvement of the Npl4 Zinc Finger Domains of SHARPIN and HOIL-1L in Linear Ubiquitin Chain Assembly Complex-Mediated Cell Death Protection
Satoshi Shimizu et al.
MOLECULAR AND CELLULAR BIOLOGY (2016)
SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling
Paul R. Elliott et al.
MOLECULAR CELL (2016)
Structure of a HOIP/E2∼ubiquitin complex reveals RBR E3 ligase mechanism and regulation
Bernhard C. Lechtenberg et al.
NATURE (2016)
Structural insights into the catalysis and regulation of E3 ubiquitin ligases
Lori Buetow et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2016)
Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease
Qing Zhou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Linear ubiquitin chain assembly complex coordinates late thymic T-cell differentiation and regulatory T-cell homeostasis
Charis E. Teh et al.
NATURE COMMUNICATIONS (2016)
Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis
Seshiru Nakazawa et al.
NATURE COMMUNICATIONS (2016)
SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes
Sebastian Kupka et al.
CELL REPORTS (2016)
Survival of mature T cells depends on signaling through HOIP
Kazumi Okamura et al.
SCIENTIFIC REPORTS (2016)
UBE2L3 Polymorphism Amplifies NF-κB Activation and Promotes Plasma Cell Development, Linking Linear Ubiquitination to Multiple Autoimmune Diseases
Myles J. Lewis et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2015)
DUBs, the regulation of cell identity and disease (vol 465, pg 1, 2014)
J. Heideker et al.
BIOCHEMICAL JOURNAL (2015)
Linear ubiquitination signals in adaptive immune responses
Fumiyo Ikeda
IMMUNOLOGICAL REVIEWS (2015)
Roles of linear ubiquitinylation, a crucial regulator of NF-κB and cell death, in the immune system
Katsuhiro Sasaki et al.
IMMUNOLOGICAL REVIEWS (2015)
The multifaceted role of the E3 ubiquitin ligase HOIL-1: beyond linear ubiquitination
Lynn Elton et al.
IMMUNOLOGICAL REVIEWS (2015)
Linear ubiquitination in immunity
Yutaka Shimizu et al.
IMMUNOLOGICAL REVIEWS (2015)
Human HOIP and LUBAC deficiency underlies autoinflammation, immunodeficiency, amylopectinosis, and lymphangiectasia
Bertrand Boisson et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2015)
The Inflammatory Caspases-1 and-11 Mediate the Pathogenesis of Dermatitis in Sharpin-Deficient Mice
Todd Douglas et al.
JOURNAL OF IMMUNOLOGY (2015)
Effect of UBE2L3 genotype on regulation of the linear ubiquitin chain assembly complex in systemic lupus erythematosus
Myles Lewis et al.
LANCET (2015)
Structures of CYLD USP with Met1-or Lys63-linked diubiquitin reveal mechanisms for dual specificity
Yusuke Sato et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
Posttranslational Modification of HOIP Blocks Toll-Like Receptor 4-Mediated Linear-Ubiquitin-Chain Formation
James Bowman et al.
MBIO (2015)
The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling
Theo Klein et al.
NATURE COMMUNICATIONS (2015)
Structures of CYLD USP with Met1-or Lys63-linked diubiquitin reveal mechanisms for dual specificity
Yusuke Sato et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
LUBAC-Recruited CYLD and A20 Regulate Gene Activation and Cell Death by Exerting Opposing Effects on Linear Ubiquitin in Signaling Complexes
Peter Draber et al.
CELL REPORTS (2015)
Mutually Exclusive Roles of SHARPIN in Integrin Inactivation and NF-κB Signaling
Nicola De Franceschi et al.
PLOS ONE (2015)
RBR E3 ubiquitin ligases: new structures, new insights, new questions
Donald E. Spratt et al.
BIOCHEMICAL JOURNAL (2014)
E3 Ubiquitin Ligase HOIP Attenuates Apoptotic Cell Death Induced by Cisplatin
Craig MacKay et al.
CANCER RESEARCH (2014)
RBR E3-ligases at work
Judith J. Smit et al.
EMBO REPORTS (2014)
Met1-linked ubiquitination in immune signalling
Berthe K. Fiil et al.
FEBS JOURNAL (2014)
Suppression of LUBAC-mediated linear ubiquitination by a specific interaction between LUBAC and the deubiquitinases CYLD and OTULIN
Tsuyoshi Takiuchi et al.
GENES TO CELLS (2014)
The linear ubiquitin assembly complex (LUBAC) is essential for NLRP3 inflammasome activation
Mary A. Rodgers et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
Mechanism Underlying IκB Kinase Activation Mediated by the Linear Ubiquitin Chain Assembly Complex
Hiroaki Fujita et al.
MOLECULAR AND CELLULAR BIOLOGY (2014)
Quantitative Proteomics Reveal a Feedforward Mechanism for Mitochondrial PARKIN Translocation and Ubiquitin Chain Synthesis
Alban Ordureau et al.
MOLECULAR CELL (2014)
Binding of OTULIN to the PUB Domain of HOIP Controls NF-κB Signaling
Veronique Schaeffer et al.
MOLECULAR CELL (2014)
Molecular Basis and Regulation of OTULIN-LUBAC Interaction
Paul R. Elliott et al.
MOLECULAR CELL (2014)
Linear ubiquitin chains: NF-κB signalling, cell death and beyond
Kazuhiro Iwai et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
New insights into ubiquitin E3 ligase mechanism
Christopher E. Berndsen et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2014)
Essential Role of the Linear Ubiquitin Chain Assembly Complex in Lymphoma Revealed by Rare Germline Polymorphisms
Yibin Yang et al.
CANCER DISCOVERY (2014)
HOIP Deficiency Causes Embryonic Lethality by Aberrant TNFR1-Mediated Endothelial Cell Death
Nieves Peltzer et al.
CELL REPORTS (2014)
TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice
James A. Rickard et al.
ELIFE (2014)
Sharpin prevents skin inflammation by inhibiting TNFR1-induced keratinocyte apoptosis
Snehlata Kumari et al.
ELIFE (2014)
Polyglucosan Body Myopathy Caused by Defective Ubiquitin Ligase RBCK1
Johanna Nilsson et al.
ANNALS OF NEUROLOGY (2013)
OTULIN Antagonizes LUBAC Signaling by Specifically Hydrolyzing Met1-Linked Polyubiquitin
Kirstin Keusekotten et al.
CELL (2013)
Defective immune responses in mice lacking LUBAC-mediated linear ubiquitination in B cells
Yoshiteru Sasaki et al.
EMBO JOURNAL (2013)
Structure of the human Parkin ligase domain in an autoinhibited state
Tobias Wauer et al.
EMBO JOURNAL (2013)
Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signalling
Rune Busk Damgaard et al.
EMBO MOLECULAR MEDICINE (2013)
Target Specificity of the E3 Ligase LUBAC for Ubiquitin and NEMO Relies on Different Minimal Requirements
Judith J. Smit et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis
Elena Rivkin et al.
NATURE (2013)
Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP
Benjamin Stieglitz et al.
NATURE (2013)
Structure of a ubiquitin-loaded HECT ligase reveals the molecular basis for catalytic priming
Elena Maspero et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)
Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains
Christoph H. Emmerich et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Structure of Parkin Reveals Mechanisms for Ubiquitin Ligase Activation
Jean-Francois Trempe et al.
SCIENCE (2013)
Structure of HHARI, a RING-IBR-RING Ubiquitin Ligase: Autoinhibition of an Ariadne-Family E3 and Insights into Ligation Mechanism
David M. Duda et al.
STRUCTURE (2013)
Linear ubiquitination: a newly discovered regulator of cell signalling
Eva Rieser et al.
TRENDS IN BIOCHEMICAL SCIENCES (2013)
Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases
B. E. Riley et al.
NATURE COMMUNICATIONS (2013)
Whole-genome DNA/RNA sequencing identifies truncating mutations in RBCK1 in a novel Mendelian disease with neuromuscular and cardiac involvement
Kai Wang et al.
GENOME MEDICINE (2013)
Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3
Hari B. Kamadurai et al.
ELIFE (2013)
Ubiquitin-Binding Proteins: Decoders of Ubiquitin-Mediated Cellular Functions
Koraljka Husnjak et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 81 (2012)
The Ubiquitin Code
David Komander et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 81 (2012)
Linear Ubiquitination of NEMO Negatively Regulates the Interferon Antiviral Response through Disruption of the MAVS-TRAF3 Complex
S. Mehdi Belgnaoui et al.
CELL HOST & MICROBE (2012)
A20 inhibits LUBAC-mediated NF-κB activation by binding linear polyubiquitin chains via its zinc finger 7
Kelly Verhelst et al.
EMBO JOURNAL (2012)
Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-κB regulation
Fuminori Tokunaga et al.
EMBO JOURNAL (2012)
The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension
Judith J. Smit et al.
EMBO JOURNAL (2012)
A non-canonical UBA-UBL interaction forms the linear-ubiquitin-chain assembly complex
Hirokazu Yagi et al.
EMBO REPORTS (2012)
LUBAC synthesizes linear ubiquitin chains via a thioester intermediate
Benjamin Stieglitz et al.
EMBO REPORTS (2012)
Structure of an E3:E2∼Ub Complex Reveals an Allosteric Mechanism Shared among RING/U-box Ligases
Jonathan N. Pruneda et al.
MOLECULAR CELL (2012)
The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity
Rune Busk Damgaard et al.
MOLECULAR CELL (2012)
Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis
Anna Plechanovova et al.
NATURE (2012)
Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency
Bertrand Boisson et al.
NATURE IMMUNOLOGY (2012)
BIRC7-E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimer
Hao Dou et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)
LUBAC regulates NF-κB activation upon genotoxic stress by promoting linear ubiquitination of NEMO
Jixiao Niu et al.
EMBO JOURNAL (2011)
Linear Ubiquitin Assembly Complex Negatively Regulates RIG-I- and TRIM25-Mediated Type I Interferon Induction
Kyung-Soo Inn et al.
MOLECULAR CELL (2011)
SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex
Fuminori Tokunaga et al.
NATURE (2011)
UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids
Dawn M. Wenzel et al.
NATURE (2011)
SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis
Fumiyo Ikeda et al.
NATURE (2011)
Linear ubiquitination prevents inflammation and regulates immune signalling
Bjoern Gerlach et al.
NATURE (2011)
SHARPIN is an endogenous inhibitor of β1-integrin activation
Juha K. Rantala et al.
NATURE CELL BIOLOGY (2011)
Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses
Daniel E. Zak et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Specific recognition of linear ubiquitin chains by the Npl4 zinc finger (NZF) domain of the HOIL-1L subunit of the linear ubiquitin chain assembly complex
Yusuke Sato et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
RING Domain E3 Ubiquitin Ligases
Raymond J. Deshaies et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2009)
NEMO oligomerization and its ubiquitin-binding properties
Frank J. Ivins et al.
BIOCHEMICAL JOURNAL (2009)
Specific Recognition of Linear Ubiquitin Chains by NEMO Is Important for NF-κB Activation
Simin Rahighi et al.
CELL (2009)
NEMO specifically recognizes K63-linked poly-ubiquitin chains through a new bipartite ubiquitin-binding domain
E. Laplantine et al.
EMBO JOURNAL (2009)
Polyubiquitination by HECT E3s and the Determinants of Chain Type Specificity
Hyung Cheol Kim et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Structural Basis for Recognition of Diubiquitins by NEMO
Yu-Chih Lo et al.
MOLECULAR CELL (2009)
Recruitment of the Linear Ubiquitin Chain Assembly Complex Stabilizes the TNF-R1 Signaling Complex and Is Required for TNF-Mediated Gene Induction
Tobias L. Haas et al.
MOLECULAR CELL (2009)
Involvement of linear polyubiquitylation of NEMO in NF-κB activation
Fuminori Tokunaga et al.
NATURE CELL BIOLOGY (2009)
Breaking the chains: structure and function of the deubiquitinases
David Komander et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
The structure of the CYLD USP domain explains its specificity for Lys63-linked polyubiquitin and reveals a B box module
David Komander et al.
MOLECULAR CELL (2008)
Optineurin negatively regulates TNFα-induced NF-κB activation by competing with NEMO for ubiquitinated RIP
Guozhi Zhu et al.
CURRENT BIOLOGY (2007)
Spontaneous mutations in the mouse Sharpin gene result in multiorgan inflammation, immune system dysregulation and dermatitis
R. E. Seymour et al.
GENES AND IMMUNITY (2007)
A ubiquitin ligase complex assembles linear polyubiquitin chains
Takayoshi Kirisako et al.
EMBO JOURNAL (2006)
Tamo selectively modulates nuclear import in Drosophila
S Minakhina et al.
GENES TO CELLS (2003)
分享论文
