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注意：仅列出部分参考文献，下载原文获取全部文献信息。The HIV-1 Vpr Protein: A Multifaceted Target for Therapeutic Intervention
Maria Eugenia Gonzalez
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Inhibition of Vpx-Mediated SAMHD1 and Vpr-Mediated Host Helicase Transcription Factor Degradation by Selective Disruption of Viral CRL4 (DCAF1) E3 Ubiquitin Ligase Assembly
Hong Wang et al.
JOURNAL OF VIROLOGY (2017)
PHF13: A new player involved in RNA polymerase II transcriptional regulation and co-transcriptional splicing
Alisa Fuchs et al.
TRANSCRIPTION-AUSTIN (2017)
A G1-like state allows HIV-1 to bypass SAMHD1 restriction in macrophages
Petra Mlcochova et al.
EMBO JOURNAL (2017)
HIV-1 Vpr Protein Induces Proteasomal Degradation of Chromatin-associated Class I HDACs to Overcome Latent Infection of Macrophages
Bizhan Romani et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
KAP1 Is a Host Restriction Factor That Promotes Human Adenovirus E1B-55K SUMO Modification
Carolin Buerck et al.
JOURNAL OF VIROLOGY (2016)
Comparative Analysis of HIV-1 and Murine Leukemia Virus Three-Dimensional Nuclear Distributions
Valentina Quercioli et al.
JOURNAL OF VIROLOGY (2016)
Calpain research for drug discovery: challenges and potential
Yasuko Ono et al.
NATURE REVIEWS DRUG DISCOVERY (2016)
HIV-1 Vpr degrades the HLTF DNA translocase in T cells and macrophages
Hichem Lahouassa et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
HIV-1 and HIV-2 exhibit divergent interactions with HLTF and UNG2 DNA repair proteins
Kasia Hrecka et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
HIV1-viral protein R (Vpr) mutations: associated phenotypes and relevance for clinical pathologies
Rui Soares et al.
REVIEWS IN MEDICAL VIROLOGY (2016)
Virion encapsidated HIV-1 Vpr induces NFAT to prime non-activated T cells for productive infection
Kristin Hoehne et al.
OPEN BIOLOGY (2016)
PHF13 is a molecular reader and transcriptional co-regulator of H3K4me2/3
Ho-Ryun Chung et al.
ELIFE (2016)
Cell Surface Proteomic Map of HIV Infection Reveals Antagonism of Amino Acid Metabolism by Vpu and Nef
Nicholas J. Matheson et al.
CELL HOST & MICROBE (2015)
SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef
Yoshiko Usami et al.
NATURE (2015)
HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation
Annachiara Rosa et al.
NATURE (2015)
Nuclear architecture dictates HIV-1 integration site selection
Bruna Marini et al.
NATURE (2015)
Fluorescent protein-tagged Vpr dissociates from HIV-1 core after viral fusion and rapidly enters the cell nucleus
Tanay M. Desai et al.
RETROVIROLOGY (2015)
Host factors for retroviral integration site selection
Zeger Debyser et al.
TRENDS IN BIOCHEMICAL SCIENCES (2015)
Vpr Promotes Macrophage-Dependent HIV-1 Infection of CD4+ T Lymphocytes
David R. Collins et al.
PLOS PATHOGENS (2015)
G2/M Cell Cycle Arrest Correlates with Primate Lentiviral Vpr Interaction with the SLX4 Complex
Gregory Berger et al.
JOURNAL OF VIROLOGY (2015)
Epigenetic Heterogeneity in HIV-1 Latency Establishment
Yuka Matsuda et al.
SCIENTIFIC REPORTS (2015)
Premature Activation of the SLX4 Complex by Vpr Promotes G2/M Arrest and Escape from Innate Immune Sensing
Nadine Laguette et al.
CELL (2014)
Vpr Overcomes Macrophage-Specific Restriction of HIV-1 Env Expression and Virion Production
Michael Mashiba et al.
CELL HOST & MICROBE (2014)
Inefficient Double-Strand Break Repair in Murine Rod Photoreceptors with Inverted Heterochromatin Organization
Antonia Frohns et al.
CURRENT BIOLOGY (2014)
HIV-1 Replication in Human Immune Cells Is Independent of TAR DNA Binding Protein 43 (TDP-43) Expression
Julia Nehls et al.
PLOS ONE (2014)
Lentiviral Nef suppresses iron uptake in a strain specific manner through inhibition of Transferrin endocytosis
Herwig Koppensteiner et al.
RETROVIROLOGY (2014)
HIV-1 Vpr-a still enigmatic multitasker
Carolin A. Guenzel et al.
FRONTIERS IN MICROBIOLOGY (2014)
Single-Cell Imaging of HIV-1 Provirus (SCIP)
Cristina Di Primio et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
HIV relies on neddylation for ubiquitin ligase-mediated functions
Michael D. Nekorchuk et al.
RETROVIROLOGY (2013)
SPOC1-Mediated Antiviral Host Cell Response Is Antagonized Early in Human Adenovirus Type 5 Infection
Sabrina Schreiner et al.
PLOS PATHOGENS (2013)
HIV-1 Vpr Accelerates Viral Replication during Acute Infection by Exploitation of Proliferating CD4+ T Cells In Vivo
Kei Sato et al.
PLOS PATHOGENS (2013)
Macrophage Internal HIV-1 Is Protected from Neutralizing Antibodies
Herwig Koppensteiner et al.
JOURNAL OF VIROLOGY (2012)
SPOC1 modulates DNA repair by regulating key determinants of chromatin compaction and DNA damage response
Andreas Mund et al.
NUCLEIC ACIDS RESEARCH (2012)
Evidence for Vpr-dependent HIV-1 replication in human CD4+ CEM.NKR T-cells
Tao Zhou et al.
RETROVIROLOGY (2012)
The TRIM Family Protein KAP1 Inhibits HIV-1 Integration
Awatef Allouch et al.
CELL HOST & MICROBE (2011)
Epigenetic displacement of HP1 from heterochromatin by HIV-1 Vpr causes premature sister chromatid separation
Mari Shimura et al.
JOURNAL OF CELL BIOLOGY (2011)
SPOC1 (PHF13) is required for spermatogonial stem cell differentiation and sustained spermatogenesis
Annegret Boerdlein et al.
JOURNAL OF CELL SCIENCE (2011)
Modulation of NKG2D-Mediated Cytotoxic Functions of Natural Killer Cells by Viral Protein R from HIV-1 Primary Isolates
Tram N. Q. Pham et al.
JOURNAL OF VIROLOGY (2011)
SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx
Nadine Laguette et al.
NATURE (2011)
Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein
Kasia Hrecka et al.
NATURE (2011)
A whole genome screen for HIV restriction factors
Li Liu et al.
RETROVIROLOGY (2011)
Immune Evasion and Counteraction of Restriction Factors by HIV-1 and Other Primate Lentiviruses
Frank Kirchhoff
CELL HOST & MICROBE (2010)
Nef Proteins from Simian Immunodeficiency Viruses Are Tetherin Antagonists
Fengwen Zhang et al.
CELL HOST & MICROBE (2009)
Tetherin-Driven Adaptation of Vpu and Nef Function and the Evolution of Pandemic and Nonpandemic HIV-1 Strains
Daniel Sauter et al.
CELL HOST & MICROBE (2009)
A Genome-wide Short Hairpin RNA Screening of Jurkat T-cells for Human Proteins Contributing to Productive HIV-1 Replication
Man Lung Yeung et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
SPOC1: a novel PHD-containing protein modulating chromatin structure and mitotic chromosome condensation
Sarah Kinkley et al.
JOURNAL OF CELL SCIENCE (2009)
The DNA-damage response in human biology and disease
Stephen P. Jackson et al.
NATURE (2009)
Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication
Renate Konig et al.
CELL (2008)
Genome-Scale RNAi Screen for Host Factors Required for HIV Replication
Honglin Zhou et al.
CELL HOST & MICROBE (2008)
The interferon-induced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu protein
Nanette Van Damme et al.
CELL HOST & MICROBE (2008)
HIV-1 Vpr-induced cell death in Schizosaccharomyces pombe is reminiscent of apoptosis
Sylvain Huard et al.
CELL RESEARCH (2008)
The ties that bind a virus to the cell
Robert P. Kruger
CELL (2008)
Identification of host proteins required for HIV infection through a functional genomic screen
Abraham L. Brass et al.
SCIENCE (2008)
Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu
Stuart J. D. Neil et al.
NATURE (2008)
Proline 35 of human immunodeficiency virus type 1 (HIV-1) Vpr regulates the integrity of the N-terminal helix and the incorporation of Vpr into virus particles and supports the replication of R5-tropic HIV-1 in human lymphoid tissue ex vivo
Joerg Votteler et al.
JOURNAL OF VIROLOGY (2007)
Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle
Kasia Hrecka et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1
Michael Schindler et al.
CELL (2006)
Effect of R77Q, R77A and R80A changes in Vpr on HIV-1 replication and CD4 T cell depletion in human lymphoid tissue ex vivo
D Rajan et al.
AIDS (2006)
Analysis of human immunodeficiency virus type 1 integration by using a specific, sensitive and quantitative assay based on real-time polymerase chain reaction
N Yamamoto et al.
VIRUS GENES (2006)
SPOC1, a novel PHD-finger protein: Association with residual disease and survival in ovarian cancer
G Mohrmann et al.
INTERNATIONAL JOURNAL OF CANCER (2005)
Human immunodeficiency virus type 1 Vpr induces the degradation of the UNG and SMUG uracil-DNA glycosylases
B Schröfelbauer et al.
JOURNAL OF VIROLOGY (2005)
The cytoplasmic body component TRIM5α restricts HIV-1 infection in Old World monkeys
M Stremlau et al.
NATURE (2004)
Increased levels of wee-1 kinase in G2 are necessary for Vpr- and gamma irradiation-induced G2 arrest
HD Yuan et al.
JOURNAL OF VIROLOGY (2004)
Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1
DM Sayah et al.
NATURE (2004)
Vpr and vpu are important for efficient human immunodeficiency virus type 1 replication and CD4+ T-cell depletion in human lymphoid tissue ex vivo
E Rücker et al.
JOURNAL OF VIROLOGY (2004)
Down-modulation of mature major histocompatibility complex class II and up-regulation of invariant chain cell surface expression are well-conserved functions of human and simian immunodeficiency virus nef alleles
M Schindler et al.
JOURNAL OF VIROLOGY (2003)
Analysis of early human immunodeficiency virus type 1 DNA synthesis by use of a new sensitive assay for quantifying integrated provirus
A Brussel et al.
JOURNAL OF VIROLOGY (2003)
Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts
B Mangeat et al.
NATURE (2003)
The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA
H Zhang et al.
NATURE (2003)
DNA determination mediates innate immunity to retroviral infection
RS Harris et al.
CELL (2003)
Hypermutation of HIV-1 DNA in the absence of the Vif protein
D Lecossier et al.
SCIENCE (2003)
HIV reproducibly establishes a latent infection after acute infection of T cells in vitro
A Jordan et al.
EMBO JOURNAL (2003)
Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method
KJ Livak et al.
METHODS (2001)
HIV-1 Vpr enhances viral burden by facilitating infection of tissue macrophages but not nondividing CD4+ T cells
DA Eckstein et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2001)
Kinetics of human immunodeficiency virus type 1 (HIV) DNA integration in acutely infected cells as determined using a novel assay for detection of integrated HIV DNA
N Vandegraaff et al.
JOURNAL OF VIROLOGY (2001)
Proteasome inhibitors: from research tools to drug candidates
AF Kisselev et al.
CHEMISTRY & BIOLOGY (2001)
A new mathematical model for relative quantification in real-time RT-PCR
MW Pfaffl
NUCLEIC ACIDS RESEARCH (2001)
The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation
A Jordan et al.
EMBO JOURNAL (2001)
3-anilino-4-arylmaleimides: Potent and selective inhibitors of glycogen synthase kinase-3 (GSK-3)
DG Smith et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2001)
Lactacystin, a proteasome inhibitor:: Discovery and its application in cell biology
H Tomoda et al.
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN (2000)
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