期刊
PARASITE
卷 24, 期 -, 页码 -出版社
EDP SCIENCES S A
DOI: 10.1051/parasite/2017012
关键词
Anti-coccidial drug; Kudoa septempunctata; ST3 genotype; Foodborne disease; Amprolium hydrochloride; Paralichthys olivaceus
类别
资金
- Ocean and Fisheries Research Institute
- Jeju Special Self-Governing Province
Kudoa septempunctata (Myxozoa: Multivalvulida) myxospores infect the trunk muscles of olive flounder (Paralichthys olivaceus). In this study, two popular commercially formulated anti-coccidial drugs (amprolium hydrochloride and toltrazuril) were serially diluted and incubated with purified mature Kudoa septempunctata myxospores. The viability of K. septempunctata spores was determined after a 2-day incubation followed by Hoechst 33342 and propidium iodide staining, and scanning electron microscopy. Amprolium hydrochloride significantly decreased spore viability (18% of control) at a concentration of 920 mu g/mL, whereas toltrazuril showed almost no effect (83% of control). Viability of the control (untreated spores) was 90%. In vivo studies are required to confirm the efficacy of amprolium hydrochloride in fish infected with K. septempunctata myxospores on their growth and immune system performance.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据