Likely Autochthonous Transmission of Trypanosoma cruzi to Humans, South Central Texas, USA

Chagas disease, caused by Trypanosoma cruzi, is a major neglected tropical disease affecting the Americas. The epidemiology of this disease in the United States is incomplete. We report evidence of likely autochthonous vectorborne transmission of T cruzi and health outcomes in T cruzi-seropositive blood donors in south central Texas, USA.