4.4 Article

Supine position and nonmodifiable risk factors for ventilator-associated pneumonia in trauma patients

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AMERICAN JOURNAL OF SURGERY
卷 213, 期 2, 页码 405-412

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EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC
DOI: 10.1016/j.amjsurg.2016.05.019

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Ventilator-associated pneumonia; Trauma; Open abdomen; Risk factors; Semiupright position; Supine position

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BACKGROUND: We studied trauma-specific conditions precluding semiupright positioning and other nonmodifiable risk factors for their influence on ventilator-associated pneumonia (VAP). METHODS: We performed a retrospective study at a Level I trauma center from 2008 to 2012 on ICU patients aged >= 15, who were intubated for more than 2 days. Using backward logistic regression, a composite of 4 factors (open abdomen, acute spinal cord injury, spine fracture, spine surgery) that preclude semiupright positioning (supine composite) and other variables were analyzed. RESULTS: In total, 77 of 374 (21%) patients had VAP. Abbreviated Injury Score head/neck greater than 2 (odds ratio [OR] 2.79, P = .006), esophageal obturator airway (OR 4.25, P = .015), red cell/plasma transfusion in the first 2 intensive care unit days (OR 2.59, P = .003), and 11 or more ventilator days (OR 17.38, P < .0001) were significant VAP risk factors, whereas supine composite, scene vs emergency department airway intervention, brain injury, and coma were not. CONCLUSION: Factors that may temporarily preclude semiupright positioning in intubated trauma patients were not associated with a higher risk for VAP. (C) 2016 Elsevier Inc. All rights reserved.

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