期刊
CHEMISTRY-A EUROPEAN JOURNAL
卷 23, 期 15, 页码 3572-3576出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201700476
关键词
actinoranone; meroterpenoid; natural products; stereochemistry; total synthesis
资金
- Shenzhen Peacock Plan [KQTD2015071714043444]
- NSFC [21572007, 21272011, 21133002]
- SZSTDF [JCYJ20160527100424909, JCYJ20150629144022829, JSGG 20160608091824706, 20140717102922014]
- GDNSF [2014A030312004, 2014B030301003]
- Fong Shu Fook Tong Foundation
- Joyce M. Kuok Foundation
The total synthesis of four actinoranone stereoisomers led to unambiguous assignment of relative and absolute stereochemistry of the natural product. Key features of the convergent, fully stereocontrolled route include the use of a Negishi carbozirconation/iodination, a Friedel-Crafts cyclization, a Felkin-controlled addition reaction, a Mitsunobu reaction, and a late-stage C-H oxidation.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据