期刊
BMC GENOMICS
卷 18, 期 -, 页码 -出版社
BMC
DOI: 10.1186/s12864-017-3650-5
关键词
Lactococcus lactis; Genomics; SMRT sequencing; Pan-genome; Niche adaptation
资金
- Department of Agriculture, Food and the Marine under the Food Institutional Research Measure (FIRM) [10/RD/TMFRC/704]
- Principal Investigator award through Science Foundation Ireland (SFI) [13/IA/1953]
- Technology Innovation Development Award (TIDA) [14/TIDA/2287]
- Science Foundation Ireland (SFI) [15/SIRG/3430]
- Science Foundation Ireland (SFI) [14/TIDA/2287] Funding Source: Science Foundation Ireland (SFI)
Background: Lactococcus lactis is among the most widely studied lactic acid bacterial species due to its long history of safe use and economic importance to the dairy industry, where it is exploited as a starter culture in cheese production. Results: In the current study, we report on the complete sequencing of 16 L. lactis subsp. lactis and L. lactis subsp. cremoris genomes. The chromosomal features of these 16 L. lactis strains in conjunction with 14 completely sequenced, publicly available lactococcal chromosomes were assessed with particular emphasis on discerning the L. lactis subspecies division, evolution and niche adaptation. The deduced pan-genome of L. lactis was found to be closed, indicating that the representative data sets employed for this analysis are sufficient to fully describe the genetic diversity of the taxon. Conclusions: Niche adaptation appears to play a significant role in governing the genetic content of each L. lactis subspecies, while (differential) genome decay and redundancy in the dairy niche is also highlighted.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据