期刊
CHEMISTRY & BIODIVERSITY
卷 14, 期 3, 页码 -出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cbdv.201600298
关键词
Marine fungus; Fusarium lateritium; Pyripyropene; Cytotoxic activities
资金
- Guangdong Provincial Science and Technology Research Program [2013B021100010, 2013B021100012, 2014A020217004, 2015A020216007, 2016A020222004]
- Fundamental Research Funds for the Central Universities [15ykpy05, 14yksh01]
- Guangdong Provincial Key Laboratory of Construction and Detection in Tissue Engineering
Two new pyripyropenes, 13-dehydroxy-1,11-deacetylpyripyropene A (1) and 1-deacetylpyripyropene A (2), together with six known compounds, were isolated from a marine fungus Fusarium lateritium 2016F18-1 which was associated with the sponge Phyllospongia foliascens. Their structures were established mainly based on NMR and MS data. Their cytotoxic activities against human cancer cells CNE1, CNE2, HONE1, SUNE1, GLC82, and HL7702 were evaluated.
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