4.3 Review

New Immunotherapy Strategies in Breast Cancer

出版社

MDPI
DOI: 10.3390/ijerph14010068

关键词

breast cancer; immunotherapy; cancer vaccines; bispecific antibodies; immune checkpoint inhibitors; stimulatory molecule agonists

资金

  1. National Science and Technology Major Project [2013ZX09509107]
  2. National Natural Science Foundation of China [81422052, 81373489, 81170091]
  3. Hunan Provincial Natural Science Foundation of China [13JJ1010]

向作者/读者索取更多资源

Breast cancer is the most commonly diagnosed cancer among women. Therapeutic treatments for breast cancer generally include surgery, chemotherapy, radiotherapy, endocrinotherapy and molecular targeted therapy. With the development of molecular biology, immunology and pharmacogenomics, immunotherapy becomes a promising new field in breast cancer therapies. In this review, we discussed recent progress in breast cancer immunotherapy, including cancer vaccines, bispecific antibodies, and immune checkpoint inhibitors. Several additional immunotherapy modalities in early stages of development are also highlighted. It is believed that these new immunotherapeutic strategies will ultimately change the current status of breast cancer therapies.

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