期刊
ANALYTICAL CHEMISTRY
卷 89, 期 8, 页码 4398-4404出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.analchem.7b00398
关键词
-
资金
- European Research Council (ERC)/ERC [636752]
- European Research Council (ERC) [636752] Funding Source: European Research Council (ERC)
Determining the properties of proteins prior to purification saves time and labor. Here, we demonstrate a native mass spectrometry approach for rapid characterization of overexpressed proteins directly in crude cell lysates. The method provides immediate information on the identity, solubility, oligomeric state, overall structure, and stability, as well as ligand binding, without the need for purification.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据