期刊
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
卷 56, 期 17, 页码 4877-4881出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201612613
关键词
biaryls; C-H activation; cross-coupling; electrochemistry; protecting groups
资金
- DFG [Wa1278/14-1]
- BMBF-EPSYLON [FKZ 12XP2016D]
The dehydrogenative cross-coupling of aniline derivatives to 2,2'-diaminobiaryls is reported. The oxidation is carried out electrochemically, which avoids the use of metals and reagents. A large variety of biphenyldiamines were thus prepared. The best results were obtained when glassy carbon was used as the anode material. The electrosynthetic reaction is easily performed in an undivided cell at slightly elevated temperature. In addition, common amine protecting groups based on carboxylic acids were employed that can be selectively removed under mild conditions after the cross-coupling, which provides quick and efficient access to important building blocks featuring free amine moieties.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据