期刊
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
卷 312, 期 4, 页码 F640-F646出版社
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/ajprenal.00369.2016
关键词
acute kidney injury; inflammation; ischemia-reperfusion; macrophages; renal fibrosis
资金
- University of Alabama at Birmingham-University of California San Diego O'Brien Center [P30 DK079337, R01 DK059600]
- NIGMS MSTP [T32GM008361]
- AHA [17PRE33370121, 16GRNT31180023]
Mononuclear phagocytes are the most common cells in the kidney associated with immunity and inflammation. Although the presence of these cells in the kidney has been known for decades, the study of mononuclear phagocytes in the context of kidney function and dysfunction is still at an early stage. The purpose of this review is to summarize the present knowledge regarding classification of these cells in the mouse kidney and to identify relevant questions that would further advance the field and potentially lead to new opportunities for treatment of acute kidney injury and other kidney diseases.
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