4.7 Article

Cobalt-catalysed Markovnikov selective hydroboration of vinylarenes

期刊

CHEMICAL COMMUNICATIONS
卷 53, 期 34, 页码 4726-4729

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c7cc01085k

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  1. University of Edinburgh
  2. Royal Society
  3. China Scholarship Council
  4. Engineering and Physical Sciences Research Council [1512100] Funding Source: researchfish

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A bipyridiyl-oxazoline cobalt catalyst (BPOCoCl2)-B-tBu has been developed for the Markovnikov selective hydroboration of alkenes using pinacolborane and (NaOBu)-Bu-t as the in situ activator with up to > 98 : 2 branched : linear selectivity (24 examples, 45-92% isolated yield).

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