期刊
BRAIN STIMULATION
卷 10, 期 3, 页码 576-578出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.brs.2017.02.005
关键词
Transcranial cerebellar direct current stimulation; Vestibular rehabilitation; Chronic dizziness; Motor learning
资金
- Japan Society for the Promotion of Science [16J40201, 26870321, 15H05880, 15H05871, 15H03044]
- Nakatomi Foundation [203150700073]
- Japan Agency for Medical Research and Development, AMED [2736040]
- STEP2 [27280201]
- Grants-in-Aid for Scientific Research [16K11205, 16J40201, 15K21731, 26870321, 15H03044, 15H05871, 15H05880, 15K10772] Funding Source: KAKEN
Background: Vestibular rehabilitation is useful to alleviate chronic dizziness in patients with vestibular dysfunction. It aims to induce neuronal plasticity in the central nervous system (especially in the cerebellum) to promote vestibular compensation. Transcranial cerebellar direct current stimulation (tcDCS) reportedly enhances cerebellar function. Objective/Hypothesis: We investigated whether vestibular rehabilitation partially combined with tcDCS is superior to the use of rehabilitation alone for the alleviation of dizziness. Methods: Patients with chronic dizziness due to vestibular dysfunction received rehabilitation concurrently with either 20-min tcDCS or sham stimulation for 5 days. Pre- and post-intervention (at 1 month) dizziness handicap inventory (DHI) scores and psychometric and motor parameters were compared. Results: Sixteen patients completed the study. DHI scores in the tcDCS group showed significant improvement over those in the sham group (ManneWhitney U test, p = 0.033). Conclusion: Vestibular rehabilitation partially combined with tcDCS appears to be a promising approach. (C) 2017 Elsevier Inc. All rights reserved.
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