期刊
MOLECULAR AND CLINICAL ONCOLOGY
卷 6, 期 5, 页码 705-707出版社
SPANDIDOS PUBL LTD
DOI: 10.3892/mco.2017.1215
关键词
alpha-fetoprotein; tonsillar metastasis; intensity-modulated radiation therapy; palliation of symptoms; survival
类别
资金
- Intramural Research Program of the NIH, National Cancer Institute, Center for Cancer Research
- NIH
- Doris Duke Charitable Foundation
- Howard Hughes Medical Institute
- American Association for Dental Research
- Colgate-Palmolive Company
Hepatoid adenocarcinoma (HAC) is a rare tumor that typically originates in gastrointestinal tissue, such as the stomach, but can also occasionally originate in the lung. The majority of HACs express alpha-fetoprotein (AFP) on tumor cells, and serum AFP can be used as a marker of response to treatment or disease progression. HAC has a poor prognosis, although early diagnosis and aggressive treatment can result in long-term survival. To the best of our knowledge, this is the first reported case of HAC metastasizing to the tonsil. Irradiation using intensity-modulated radiation therapy (IMRT) to 30 Gray (Gy) achieved a significant, and durable tumor response. IMRT can be considered for local control of HAC at other metastatic sites of disease.
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