期刊
CHEMICAL COMMUNICATIONS
卷 53, 期 35, 页码 4791-4794出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7cc01695f
关键词
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资金
- National Creative Research Initiative programs of the National Research Foundation of Korea (NRF) - Korean government (MSIP) [2012R1A3A2048814]
- GRRC program of Gyeonggi province [GRRC AJOU 2016B02]
Hydrogen sulfide (H2S) is a signaling gasotransmitter, which plays various roles in modulating the functions of different systems. In this study, a turn-on'' fluorescent probe for H2S was developed. The probe, whose design is based on a familiar excited state intramolecular proton transfer (ESIPT) fluorophore bearing aggregation-induced emission (AIE) characteristics, was found to exhibit an 80-fold fluorescence enhancement along with a large Stokes shift upon the addition of H2S. Furthermore, the probe was successfully utilized to detect H2S in HeLa cells with both one-photon and two-photon microscopy.
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