期刊
EMBO JOURNAL
卷 36, 期 8, 页码 959-963出版社
WILEY
DOI: 10.15252/embj.201796837
关键词
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资金
- NIA NIH HHS [P01 AG047200, R03 AG052365, R01 AG046320] Funding Source: Medline
Aging is one of the greatest challenges for biomedical research in the developed world. The continuing increase in lifespan without accompanying increases in health span has extreme economic and societal implications for an aging society. The majority of adult-onset diseases such as cancer, cardiovascular disease, and Alzheimer's are a direct consequence of aging, and with changing demographics, more and more people are afflicted. If we knew how to slow down the negative effects of aging, we could delay or prevent all of these diseases at once. We therefore need to understand the underlying molecular mechanisms of aging and longevity so as to develop applications that ultimately improve health span.
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