期刊
ANALYTICAL METHODS
卷 9, 期 15, 页码 2284-2289出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7ay00577f
关键词
-
资金
- CNPq (Conselho Nacional de Desenvolvimento Cientifico e Tecnologico)
In this paper an analytical method was developed for the determination of some tobacco specific N-nitrosamines (TSNAs) in cigarettes, and applied to cigarettes purchased in the city of Rio de Janeiro/RJ (Brazil). The analyte detection is based on the gas chromatography technique with a chemiluminescence detector (GC-NCD), while the extraction is based on two stages, the first is a cigarette leaching step, and the other is solid phase extraction of TSNAs from this leaching. The method presented an accuracy of 92 + 18%; the precision was calculated using the coefficient of variation of a standard TSNA mix solution measured on 3 successive days and was in the range from 4.7 to 6.8%. The working range of all TSNAs was 50-700 ng mL(-1), allowing the method to have LOQ values from 198.3 to 623.7.1 ng per cig. The method developed allowed determination of NNN, NAT, NNK and NAB in commercial cigarette samples.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据