期刊
BMC ANESTHESIOLOGY
卷 17, 期 -, 页码 -出版社
BMC
DOI: 10.1186/s12871-017-0434-z
关键词
Obesity; Overweight; Sepsis; Septic shock; Obesity paradox; Mortality; ICU; Meta-analysis
资金
- Merck Inc.
While the long-term negative effects of obesity on health is a well-studied phenomenon, its effects on acute illnesses seem to be the contrary. Several studies have indicated the possibility of an 'obesity paradox' in sepsis - where overweight and obese patients have better outcomes than normal weight patients. These meta-analyses including large numbers of patients across different countries raised an interesting but debatable topic. Results from metaanalyses of observational studies should be interpreted with caution, and a prove of association not be mistaken as prove of causality. Limitations common to such studies include inadequate adjustment for confounding and selection bias. More rigorous investigations to clarify any causal relationship between obesity and mortality in sepsis are needed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据