Fluorescent Sensor for Rapid Detection of Nucleophile and Convenient Comparison of Nucleophilicity

Although nucleophile (Nit) is associated with many important chemical-reactions, there are no fluorescence sensors for,Nu detectibn and even for calculation of its nucleophilicity up to the present. In this study, we developed a.fluorescent malononitrile-modified perylenediimide (MAPDI) which can-selectively and rapidly react with nucleophiles, such as amines, amino acids, and some inorganic anions) and then change its UV vis absorption and.fluorescence emission. Detection hilts of MAPDI for differeut nucleophiles Could be calculated, to compare their strength of nucleophilicity. Furthermore, it was found that MAPDI could detect reductive inorganic anions. These-results suggested that MAPDI might have.a great potential in organocatalytic reactions; metal ion catalyzed reactions, reactions of amities, and other nucleophilic chemical reactions.