期刊
CURRENT OPINION IN ORGAN TRANSPLANTATION
卷 22, 期 3, 页码 287-289出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MOT.0000000000000404
关键词
ex-vivo lung perfusion; lung preservation; lung transplantation; organ procurement center
资金
- XVIVO Perfusion
- United Therapeutics
Purpose of review Lung evaluation and reconditioning by ex-vivo lung perfusion (EVLP) is becoming increasingly established. We review strategies for broader implementation of this technology to transplant centers worldwide. Recent findings The organ reconditioning hub model is a viable strategy for disseminating EVLP to small and large transplant centers given the well tolerated prolongation of preservation time afforded by EVLP. Regulatory and process issues remain hurdles to be overcome. Summary EVLP demonstrates promise to increase lung utilization. Organ reconditioning hubs appear to be an efficient method of delivering this promise to all transplant centers, not necessarily only the largest ones. Organ allocation processes will need to adapt to this new paradigm of organ preservation
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