期刊
THERANOSTICS
卷 7, 期 10, 页码 2575-2592出版社
IVYSPRING INT PUBL
DOI: 10.7150/thno.20118
关键词
Cell membrane; Nanoparticle; Camouflage; Cancer
资金
- National Basic Research Program of China [2014CB931900]
- National Natural Science Foundation of China [81521005, 81630052, 81671808]
- Key scientific research program of CAS [QYZDJ-SSW-SMC020]
- Shanghai Pujiang Program [15PJ1409900]
- Youth Innovation Promotion Association of CAS [2017335]
Cancer is one of the leading causes of death worldwide. Many treatments have been developed so far, although effective, suffer from severe side effects due to low selectivity. Nanoparticles can improve the therapeutic index of their delivered drugs by specifically transporting them to tumors. However, their exogenous nature usually leads to fast clearance by mononuclear phagocytic system. Recently, cell membrane-camouflaged nanoparticles have been investigated for cancer therapy, taking advantage of excellent biocompatibility and versatile functionality of cell membranes. In this review, we summarized source materials and procedures that have been used for constructing and characterizing biomimetic nanoparticles with a focus on their application in cancer therapy.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据