4.7 Article

Domestic Pig Unlikely Reservoir for MERS-CoV

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EMERGING INFECTIOUS DISEASES
卷 23, 期 6, 页码 985-988

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CENTERS DISEASE CONTROL
DOI: 10.3201/eid2306.170096

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  1. Intramural Research Program of the National Institute of Allergy and Infectious Diseases of the National Institutes of Health

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We tested the suitability of the domestic pig as a model for Middle East respiratory syndrome coronavirus (MERS-CoV) infection. Inoculation did not cause disease, but a low level of virus replication, shedding, and seroconversion were observed. Pigs do not recapitulate human MERS-CoV and are unlikely to constitute a reservoir in nature.

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